Production method of water-soluble hemostatic gauze

Abstract

The invention discloses a production method of water-soluble hemostatic gauze. The production method comprises the following steps: carrying out sterilizing process on natural full-cotton gauze after preprocessing, sitallization processing, cross linking reaction, washing and drying, wherein the preprocessing is realized by modifying the natural full-cotton gauze by using ethanol or acetone; the sitallization processing is carried out for 1-2h by adopting a sodium hydroxide solution under the condition that the temperature is 20-30 DEG C and the rotational speed of a reaction vessel is 15-20 r / min; and the cross linking reaction is carried out for 1-2h at the temperature of 25-30 DEG C by adopting an ethanol chloroactic acid solution. The water-soluble hemostatic gauze has favorable functions of physical hemostasis, chemical hemostasis and physiological hemostasis, can rapidly realize hemostasis and diminish inflammation without medicaments, also prevent operation conglutination and be finally decomposed in the body to form monosaccharide absorbed by a human body.

Description

technical field [0001] The invention relates to the field of medical supplies, in particular to a method for making water-soluble hemostatic gauze. Background technique [0002] With the rapid development of health care and medicine, the requirements for medical equipment are gradually developing in the direction of high, refined and beautiful. Medical gauze is an important commonly used medical dressing, which has the characteristics of large usage and wide application. However, when it comes to various departments such as surgery, facial features, gynecology, and burns, many problems and accidents caused by conventional gauze cannot be solved for a while, such as repeated infection of the dressing, exacerbating the suffering of patients due to dressing changes, and the negligence of medical staff. Cause the viscera to be left behind and become a serious disaster, the environmental pollution of discarded pus and blood gauze and so on. Therefore, the international medical ...

AI Technical Summary

Problems solved by technology

Gelatin sponge, gelatin fiber, artificial water-soluble mixed coating, etc., which can barely be used as auxiliary products, cannot completely replace medical gauze due to either poor hemostatic function or insufficient strength

In recent years, some people have envisioned the production of water-soluble hemostatic fiber, but it is still difficult to apply it in practice due to the shortcomings of complicated process, long reaction time, high production cost, and unsafe raw materials.

Such as Chinese patent CN1286329 provides a kind of water-soluble hemostatic fiber and preparation method thereof, but, according to the production process of this patent embodiment 1,3,5,6, find that the product produced has fiber agglomeration, yellowing, texture Hard and other shortcomings, and through the water solubility test, there is still insoluble matter more than 24 hours; Chinese invention CN101284144 provides a kind of soluble hemostatic cotton, in actual use, there is a small area of ​​use, and it cannot be used in large areas of burns and scalds. Planar surgical wounds such as obstetrics and gynecology cesarean section can not be used and other shortcomings; Chinese patent CN1186490 discloses a hydroxyethyl modified cotton fiber fabric and its preparation method, there is a risk of explosion of the raw material ethylene oxide, Moreover, this raw material is toxic. After a large amount of use, even after washing, it is difficult to ensure that there is no residue of this substance or molecule at all, causing the product to have certain disadvantages such as insecurity.