Verticillium cereus immediate-release dispersible tablet and preparation method thereof

Abstract

The invention discloses a Verticillium cereus immediate-release dispersible tablet and a preparation method thereof. agents, disintegrants, wetting agents, fillers and lubricants. The preparation method is as follows: firstly, 2 / 3 of the disintegrating agent and other auxiliary agents and Verticillium cereus are added in a mixer according to a certain proportion and mixed evenly, and then an appropriate amount of wetting agent is added to mix to form a wet material, and it is made by passing through a 20-mesh sieve. For wet granules, after drying at room temperature for 24-48 hours under relatively sterile conditions, add the remaining 1 / 3 of the disintegrant to the dry granules and weigh them, add 0.5-0.6% of the granule weight lubricant and mix well, Enter the tablet press and press it into large pieces with appropriate pressure to obtain the finished product. The product has a simple production process, a wide range of raw material sources, and is easy to industrialize. It can rapidly disintegrate and release active ingredients in water, has a fast onset of action, has no dust pollution, has a wide range of control, and can kill insects and inhibit bacteria at the same time.

Description

technical field [0001] The invention belongs to the production and processing technology of fungal microbial pesticides in the field of biological control, and in particular relates to specific insecticidal and bactericidal microbial pesticides for Verticillium lecanii. Background technique [0002] Verticillium lecanii was discovered in 1861 until the 1950s when foreign countries started in-depth research and popularized applications. Up to now, more than a dozen products have been industrialized and put on the market. They are used to control whitefly in cucumbers and tomatoes in greenhouses. significantly. However, my country has only started research since the 1970s. There have been small-scale applications of experimental products, but there have been no relevant reports on large-scale field application, and there is still no product registration. The main reason is that the process technology and formulation development suitable for industrial production Relatively lag...

AI Technical Summary

Problems solved by technology

[0004] At present, domestic research on its dosage form and its additives is still in the exploratory stage, and the relevant research is mainly made into wettable powder, but it is easy to cause dust pollution, and the dose controllability is poor, resulting in waste and safety for producers and users The coefficient is reduced, and the main active ingredient of the wettable powder produced by the prior art is the mixture of spores, mycelium and culture medium, and the content of the active ingredient per unit volume is too low, which indirectly increases the agricultural cost and limits its large-scale production. Scale promotion and application

In addition, under the current technical conditions, the drying process of the main component in the production of its wettable powder is a high-cost production link, which limits its further large-scale industrial production

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