Carteolol orally disintegrating tablets and preparation method thereof

A technology of orally disintegrating tablets and hydrochloric acid cards, which is applied in the field of pharmaceutical preparations, can solve the problems that have not yet been reported on carteolol hydrochloride orally disintegrating tablets, and achieve the effects of good medication compliance, convenient taking, and broad market prospects
CN101690720AInactive Publication Date: 2010-04-07SOUTHWEST UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SOUTHWEST UNIVERSITY
Publication Date
2010-04-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses carteolol orally disintegrating tablets and a preparation method thereof. The orally disintegrating tablets comprise the following compositions in percentage by mass: 0.1 to 10 percent of carteolol, 50 to 90 percent of filler, 5 to 40 percent of disintegrating agent, 0.1 to 5 percent of lubricant and 0.1 to 5 percent of flavoring agent. The orally disintegrating tablets can be quickly disintegrated in oral cavity, has quick absorption, quick response, small first-pass effect of the liver, high biological utilization rate and small irritation on gastrointestinal tract, is convenient for taking, has excellent taste and is particularly suitable for old people, children and patients with swallow difficulty or drinking inconvenience. The orally disintegrating tablets are prepared by adopting a wet granulation and tableting method or a direct powder tableting method, have simple manufacture process, low cost, easily controlled quality, stable preparation, safety and efficiency, are applicable to large-scale industrial production and have wide market prospect.
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Description

technical field

[0001] The invention relates to a pharmaceutical preparation, in particular to a carteolol hydrochloride oral disintegrating tablet, and also to a preparation method of the oral disintegrating tablet. Background technique

[0002] Tablet is a traditional pharmaceutical dosage form, which has become one of the most commonly used pharmaceutical dosage forms at present because of its advantages of stable quality, accurate dosage, convenient taking and carrying, high degree of mechanization, and low production cost. Slow disintegration, low bioavailability, and difficulty in swallowing for some patients are limited in application to a certain extent. To this end, oral solid immediate-release preparations have become one of the hotspots in the research and development of new drugs in recent years, and oral disintegrating tablets, dispersible tablets and sublingual tablets are emerging. Orally disintegrating tablet is a kind of tablet that can disintegrate or diss...

Claims

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