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Application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in auxiliary way

The technology of health food and sunflower leaf is applied in the application field of sunflower leaf used for preparing food and auxiliary blood pressure lowering health food, and achieves the effects of no side effects, heat-clearing and diuretic effect, and clear blood pressure lowering mechanism.

Active Publication Date: 2010-09-01
SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, sunflower leaves have not been used as a new resource of medicine and food for market development for large-scale production to prepare food and health food, especially the application of food and health food used in hypertensive patients

Method used

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  • Application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in auxiliary way
  • Application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in auxiliary way

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The animal preliminary experiment of embodiment 1 sunflower leaf diuresis

[0021] 1. Purpose of the test:

[0022] Observe the effect of various sunflower leaf extracts on the urine output of mice by intragastric administration.

[0023] 2. Test material:

[0024] 2.1 Test products: water extract of sunflower leaves, alcohol extract of sunflower leaves, fermented extract of sunflower leaves, effective parts of sunflower leaves, all are powders, numbered 1, 2, 3, and 4 respectively. When in use, they were sonicated for 20 minutes to prepare corresponding concentrations, and stored in a refrigerator at 4°C for test use.

[0025] 2.2 Reference substance: furosemide tablets, white tablets. 100 tablets / bottle, 20mg / tablet.

[0026] 2.3 Vehicle: sodium chloride injection, specification: 500ml: 4.5g.

[0027] 2.4 Experimental animals: Kunming mice, normal grade, male, 28-32g.

[0028] 3. Experimental method: 60 healthy mice were selected and randomly divided into 6 grou...

Embodiment 2

[0035] The pharmacological preliminary test of embodiment 2 sunflower leaves depressing blood pressure

[0036] 1. The purpose of the experiment:

[0037] To observe the antihypertensive effect of antihypertensive samples administered intragastrically on normotensive rats.

[0038] 2. Experimental materials:

[0039] 2.1 Test product:

[0040] Sunflower leaf water extract, sunflower leaf alcohol extract, sunflower leaf fermented extract, and sunflower leaf effective fractions are all solid, numbered 1, 2, 3, and 4 respectively. When in use, ultrasonically treat at 40KHZ 40°C for 20 minutes to prepare the corresponding concentration, and store in a refrigerator at 4°C for test use.

[0041] 2.2 Positive control substance: Compound Apocynum I (6 tablets per day).

[0042] 2.3 Experimental animals: 20 Wistar female rats, normal grade, weighing 250-300 g.

[0043] 2.4 Main equipment: non-invasive tail artery blood pressure measurement and analysis system.

[0044] 3. Experim...

Embodiment 3

[0054] Embodiment 3 The preparation of sunflower leaf auxiliary antihypertensive drink

[0055] Formula: 10kg of sunflower leaves, 7.0kg of liquid xylitol, 0.16kg of protein sugar, and 0.32kg of citric acid.

[0056] Preparation of sunflower leaf fermentation broth: 10kg of oriented sunflower leaves, water extraction 2 times, each time for 1h, filtered, the filtrate was concentrated to a concentrated solution with a relative density of 1.10-1.18 (60°C), put it in a closed container, and added 1kg of sucrose, Bring to a boil and cool. Kombucha, lactic acid bacteria and bifidobacterium strains are inserted, and fermented in a closed container at room temperature for 3 to 4 days. After the fermentation is finished, filter the sterilizing film, and get the filtrate.

[0057] Preparation: Weigh liquid xylitol, protein sugar, citric acid, etc. according to the formula ratio, add appropriate amount of water to fully dissolve, filter through a double filter, mix with sunflower leaf ...

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Abstract

The invention discloses an application of sunflower leaves for preparing foods and health-care foods for reducing blood pressure in an auxiliary way. The research of the inventor indicates that the sunflower leaves have obvious effects on promoting digestion and strengthening the stomach, reducing fever and causing diuresis and reducing blood pressure, have explicit mechanism of action, have no toxic side effect on human bodies, and can be widely used for preparing the foods and health-care foods for reducing blood pressure in an auxiliary way. The prepared foods and health-care foods can be applied to all people and especially patients with hypertension.

Description

technical field [0001] The invention relates to the application of sunflower leaves for food preparation and health food for assisting blood pressure reduction. Background technique [0002] Essential hypertension is a common and frequently-occurring disease clinically. It is an independent disease whose etiology is not yet clear and whose main clinical manifestation is elevated blood pressure. Although hypertension is relatively independent in terms of disease classification, it is an important risk factor for stroke, coronary heart disease, renal failure, and fundus lesions. It is a disease that seriously endangers human health and affects the quality of life. According to statistics, the prevalence of hypertension among residents aged 18 and over in my country is 18.8%, which is an increase of 31% compared with 1991. At present, the number of hypertensive patients in my country has reached 160 million. Therefore, it is of great significance to the prevention and treatmen...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K36/28A61P9/12A61K127/00A23L33/00
Inventor 张玲凌沛学尚立霞
Owner SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES
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