Controllablely degradable internal fixation composite material and preparation method and application thereof

A technology of composite materials and composite powders, which is applied in the fields of internal bone synthesis, fixers, medical science, etc., can solve the problems of affecting the mechanical properties of composite materials, the neutralization effect needs to be improved, and the burden and pain of patients will be increased, so as to achieve a good industrialization prospect , promote bone healing, improve biocompatibility
CN101991881BInactive Publication Date: 2013-07-31TIANJIN UNIVERSITY OF TECHNOLOGY

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
TIANJIN UNIVERSITY OF TECHNOLOGY
Publication Date
2013-07-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a controllable degradable internal fixation composite material, which consists of the following components in percentage by weight: 8 to 15 percent nanorod-shaped hydroxyapatite granule, 2 to 5 percent of magnesium granule and the balance of polylactic acid. The composite material is used for manufacturing bone screws, namely magnesium-nano hydroxyapatite / polylactic acid composite material is injected and molded into absorbable bone screws by an injection molding machine in the specification of 10 to 90g. The invention has the advantages that: rod-shaped n-HA granules and Mg granules are introduced into a polylactic acid matrix, wherein the rod-shaped n-HA granules can improve the toughness and bioactivity of the composite material, and the added Mg granules can neutralize the local acid environment of the degraded polylactic acid in vivo to reduce the irritation on human tissues. Meanwhile, the composite material is easy to prepare and low in cost, and has good industrial prospect.
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Description

technical field

[0001] The invention relates to a biodegradable internal bone fixation material and a preparation method thereof, belonging to the technical field of preparation of materials for medical surgery. Background technique

[0002] Medical metal materials such as stainless steel, cobalt-based alloys, titanium alloys, etc., are currently the most widely used fracture internal fixation materials. However, metal internal fixators made of the above-mentioned fixing materials have obvious defects: 1) The rigidity is much greater than that of cortical bone. 2) Under the action of physiological corrosion and wear, toxic metal ions and microparticles may be released, causing local tissue inflammation; 3) The material cannot be degraded, and it must be removed by a second operation after bone healing, which increases the patient's Economic and psychological burden and physical pain. Therefore, in bone injury surgery, the use of in vivo degradable materials instead of trad...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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