Metronidazole, clotrimazole and chlorhexidine acetate vagina gel and preparation method thereof

The invention discloses a metronidazole, clotrimazole and chlorhexidine acetate vagina gel and a preparation method thereof. Every 1000g of gel comprises the following components by weight: 40g of metronidazole, 32g of clotrimazole, 1.6g of chlorhexidine acetate, 10g of Carbomer 934, 120g of glycerol, 4g of triethanolamine, 1g of ethylparaben and the balance pure water. The method comprises the following steps: (1) mixing the metronidazole, clotrimazole and chlorhexidine acetate based on respective weight, and crushing evenly and sieving for later use; (2) preparing the Carbomer 934, triethanolamine and pure water into a matrix based on respective weight; (3) adding glycerol, ethylparaben into the crushed components in the step (1), and stirring evenly to obtain a mixture for later use; (4) adding pure water into the mixture of the step (3), mixing evenly to prepare into 1000g of gel; and (5) carrying out encapsulation on the gel obtained in the step (4) to obtain the product of the metronidazole, clotrimazole and chlorhexidine acetate vagina gel. The metronidazole, clotrimazole and chlorhexidine acetate vagina gel disclosed by the invention has excellent treating effects, and is a medicine which is convenient to use, is non-irritant, and has no foreign body sensation and good curative effect.