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Biological colloid dispersant used for wound-protection and its preparation method

A technology of biocolloid and dispersant is applied in the preparation of the biocolloid dispersant for wound care, in the field of biocolloid dispersant for wound protection, and can solve problems such as maintaining stability, achieve less process steps, no side effects, no peculiar smell, and shorten healing time. effect of time

Inactive Publication Date: 2011-10-19
苏州汇涵医用科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Moreover, it is difficult for animal gelatin for medical use to be reliably stable during the two-year guarantee period, that is, without deterioration

Method used

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  • Biological colloid dispersant used for wound-protection and its preparation method
  • Biological colloid dispersant used for wound-protection and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A) Add 0.12g of ultra-fine silver ion powder of 10-50 nanometers produced and sold by Shenzhen Zhiyuan Kejia Technology Co., Ltd., Guangdong Province, China to 8g of commercially available and measured by conductivity meter Stir evenly in deionized water with a purity of 0.1-0.16 μs / cm. The container used can be a polyethylene plastic container or a stainless steel container until the silver ion powder is fully dissolved to obtain a silver ion powder liquid;

[0027] B) 0.5g of reagent-grade phosphoric acid is added to the silver ion powder liquid obtained in step A) to carry out acidification treatment, the time of acidification treatment is 30min, and the pH is adjusted to 1.8 to obtain the silver ion powder mixed solution after acidification treatment ;

[0028] C) adding 0.4 g of reagent-grade tartaric acid obtained commercially, such as produced and sold by China Shanghai Reagent No. 1 Factory, into 8 g of deionized water with the same purity of 0.1-0.16 μs / cm and ...

Embodiment 2

[0034] A) Add 0.25g of ultra-fine silver ion powder of 10-50 nanometers produced and sold by Shenzhen Zhiyuan Kejia Technology Co., Ltd., Guangdong Province, China to 10g of commercially available and measured by conductivity meter Stir evenly in distilled water with a purity of 0.1-0.16μs / cm. The container used can be either a polyethylene plastic container or a stainless steel container until the silver ion powder is fully dissolved, thereby obtaining a silver ion powder liquid;

[0035] B) 0.8g of reagent-grade phosphoric acid is added to the silver ion powder liquid obtained in step A) to carry out acidification treatment, the time of acidification treatment is 15min, and the pH is adjusted to 1.5 to obtain the silver ion powder mixed solution after acidification treatment ;

[0036] C) adding 0.6 g of reagent-grade tartaric acid obtained commercially, such as produced and sold by China Shanghai Reagent No. 1 Factory, into 10 g of distilled water with the same purity of 0....

Embodiment 3

[0041] A) Add 0.4g of ultra-fine silver ion powder of 10-50 nanometers produced and sold by Shenzhen Zhiyuan Kejia Technology Co., Ltd., Guangdong Province, China to 15g of commercially available and measured by conductivity meter Stir evenly in deionized water with a purity of 0.1-0.16 μs / cm. The container used can be a polyethylene plastic container or a stainless steel container until the silver ion powder is fully dissolved to obtain a silver ion powder liquid;

[0042] B) adding 1 g of reagent-grade citric acid to the silver ion powder liquid obtained in step A) to carry out acidification treatment, the time of acidification treatment is 40min, adjust pH2, and obtain the silver ion powder mixed solution after acidification treatment;

[0043] C) adding 0.8 g of reagent-grade tartaric acid obtained commercially, such as produced and sold by China Shanghai Reagent No. 1 Factory, into 13 g of deionized water with the same purity of 0.1-0.16 μs / cm and stirring for 15 minutes t...

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Abstract

The invention relates to a biological colloid dispersant used for wound-protection and its preparation method, which belongs to the technical field of medical surgical drugs. The invention is characterized in that every 1000g weight of a finished product dispersant comprises: 0.12 to 4g of ultrafine silver ion powder, 0.06 to 0.44g of sodium alginate, 0.5 to 1g of tribasic acid, 14.5 to 16g of osmotic agent, 0.4 to 0.8g of tartrate and the balance of pure water, wherein: the tribasic acid is any one type of phosphoric acid or citric acid, the osmotic agent is hydrogen peroxide. The invention has the advantages of security, stability and environmental protection performance; the invention has the ideal penetration effect, which is used for shortening the healing time of wound as well as the treatment period; the biological colloid dispersant used for wound-protection has the advantages of no side effect on patients, no abnormal odor and no sensitization; the preparation method has the merits of less process step and no harsh condition, which can adopt a mass production requirement.

Description

technical field [0001] The invention belongs to the technical field of medicine for medical surgery, specifically relates to a biological colloid dispersant for wound protection, and also relates to a preparation method of the biological colloid dispersant for wound protection, which is suitable for infection control of human body surface wounds and promotion of wound healing . Background technique [0002] In the narration of the first line of the first page of the first page to the second page of the authorization announcement number CN100560057C and the name of the description of the wound protection liquid and its preparation method proposed by the applicant, the domestic and foreign recognized such as burns, scalds and open wounds The three shortcomings of the wound infection medication—silver sulfadiazine cream (also known as ointment) or suspensions caused by such situations as those mentioned above—were objectively evaluated. And to prior art such as CN1090905C (str...

Claims

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Application Information

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IPC IPC(8): A61K33/38A61K9/10A61K47/36A61P17/02A61P31/04
Inventor 孟孝平吴军朱世辉张琦冯永良
Owner 苏州汇涵医用科技发展有限公司
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