Composition chewable tablet of zinc gluconate compound and its preparation method
A technology of zinc gluconate and composition, applied in the direction of drug combination, non-active ingredient medical preparations, medical preparations containing active ingredients, etc., can solve the problems of low absorption rate and achieve high absorption rate and small side effects Effect
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[0026] Example 1
[0027] The preparation method of a chewable tablet of zinc gluconate compound composition in the embodiment of the present invention consists of the following steps:
[0028] (1) Weigh 35g zinc gluconate, 1g vitamin C, 4g folic acid, 1.2g xylitol, and
[0029] Pear alcohol 2.8g, maltodextrin 9g, malic acid 13g, orange flavor 25g, aspartame 8g, magnesium stearate 1g;
[0030] (2) Put the weighed xylitol and sorbitol into a mortar and mix them evenly, pass through a 90-mesh sieve for use;
[0031] (3) Add water to the weighed maltodextrin to prepare solution A with a mass concentration of 5%;
[0032] (4) Mix the weighed zinc gluconate, vitamin C, folic acid, malic acid and orange flavor evenly, slowly add solution A, while constantly stirring, to make soft material B with moderate hardness;
[0033] (5) Using a 14-mesh sieve as a granulating tool, tightly hold the soft material B into a mass and press it through the 14-mesh sieve to make the soft material B into small pa...
Example Embodiment
[0036] Example 2
[0037] The preparation method of a chewable tablet of zinc gluconate compound composition in the embodiment of the present invention consists of the following steps:
[0038] (1) Weigh 38g of zinc gluconate, 2g of vitamin C, 6g of folic acid, 1.8g of xylitol, 3.6g of sorbitol, 20g of maltodextrin, 6g of malic acid, 16g of orange essence, 5g of aspartame, and stearin. Magnesium acid 1.6g;
[0039] (2) Put the weighed xylitol and sorbitol into a mortar and mix them evenly, pass through an 80 mesh sieve for use;
[0040] (3) Add water to the weighed maltodextrin to prepare a solution A with a mass concentration of 3%;
[0041] (4) Mix the weighed zinc gluconate, vitamin C, folic acid, malic acid and orange flavor evenly, slowly add solution A, while constantly stirring, to make soft material B with moderate hardness;
[0042] (5) Using a 15-mesh sieve as a granulating tool, tightly hold the soft material B into a mass, and press it through the 15-mesh sieve to make the s...
Example Embodiment
[0045] Example 3
[0046] The preparation method of a chewable tablet of zinc gluconate compound composition in the embodiment of the present invention consists of the following steps:
[0047] (1) Weigh 40g of zinc gluconate, 3g of vitamin C, 1.5g of folic acid, 1g of xylitol, 4g of sorbitol, 6g of maltodextrin, 5g of malic acid, 30g of orange flavor, 9g of aspartame, and stearic acid. Magnesium 0.5g;
[0048] (2) Put the weighed xylitol and sorbitol into a mortar and mix them evenly, pass through a 100-mesh sieve for use;
[0049] (3) Add water to the weighed maltodextrin to prepare a solution A with a mass concentration of 10%;
[0050] (4) Mix the weighed zinc gluconate, vitamin C, folic acid, malic acid and orange flavor evenly, slowly add solution A, while constantly stirring, to make soft material B with moderate hardness;
[0051] (5) Using a 12-mesh sieve as a granulating tool, tightly hold the soft material B into a mass and press it through the 12-mesh sieve to make the soft ...
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