Raw material pretreatment method for improving dissolution rate of active ingredients of medicinal plants

Abstract

The invention discloses a raw material gas explosion pretreatment method for improving the dissolution rate of active ingredients of medicinal plants. The method comprises the following steps of: putting materials preimpregnated in water or aqueous solution into a high-pressure container, sealing, introducing a medium, keeping the temperature between 40 and 250 DEG C for 0.5 to 30 minutes, releasing pressure quickly, and discharging the materials in the high-pressure container to a normal-pressure container to obtain materials which are subjected to gas explosion pretreatment, wherein the medium is one or a combination of two of air, carbon dioxide, ozone, liquid nitrogen, nitrogen, water vapor and supercritical CO2. On the basis of the bioactivity of the active ingredients of the medicinal plants, various medium combination gas explosion modes in the low-temperature and high-pressure state are adopted selectively to ensure the treatment strength of the materials, and the dissolution rate of the active ingredients is improved on the premise that the active ingredients are not damaged to improve the utilization rate of raw materials; and the method is quick, simple, economic, high in adaptation degree and wide in selective range, and pollution is avoided, so the method is a significant path for realizing high-value utilization of the medicinal plants.

Description

technical field [0001] The invention belongs to the application field of medicinal plants, in particular to a raw material pretreatment method for improving the dissolution rate of active ingredients of medicinal plants. Background technique [0002] Under the influence of population aging, global medical system reform, health care and the world trend of "returning to nature", the application scope and usage rate of traditional medicine in the world are constantly increasing, and the space in the international market is constantly expanding, showing worldwide It has a good development opportunity and a very broad development prospect. According to the estimates of the World Health Organization, 80% of the world's population is currently using or has used various traditional medicines for treatment and health care, and traditional medicines generally use medicinal plants as the main materials. Medicinal plants are the general term for plants that contain substances with cert...

AI Technical Summary

Problems solved by technology

Therefore, no matter what extraction method is used, the degree of damage to plant cells will directly affect the extraction efficiency and subsequent processing.

[0005] Traditional methods generally use mechanical pulverization to crush materials, but because plant cells have great resistance to external forces, the degree of damage to plant cells by mechanical treatment is limited

However, if the plant-based traditional Chinese medicine is to be crushed to the micron level, the energy consumption will increase and the cost will increase.