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Preparation method of ointment for improving skin itch of urogenital canal

A technology for urogenital tract and skin pruritus, applied in the directions of medical preparations containing active ingredients, skin diseases, ointment delivery, etc. Improved survival and quality of life, high morbidity

Active Publication Date: 2013-02-20
吉林省东北亚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs can control the symptoms of the patient's condition to a certain extent, once the patient stops using the drug, the condition will recur and even lead to further aggravation of the condition.
And this kind of medicine usually can produce bigger side effect to human body, can not eradicate the cause of the disease, easily lead to the generation of disease relapse phenomenon.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The required raw materials are calculated in parts by weight: 9 parts of honeysuckle, 5 parts of sealwort, 2 parts of dried ginger, 9 parts of scallion, 5 parts of raspberry, 2 parts of donkey-hide gelatin, 2 parts of oyster, 150 parts of propylene glycol, and 10 parts of potassium hydroxide , 200 parts of glycerin, 45 parts of azone, 210 parts of stearic acid, 95 parts of stearyl alcohol, 45 parts of glyceryl monostearate, 4 parts of methyl paraben, 0.5 parts of chlorhexidine acetate, 80 parts of volatile oil Tween 10 parts of clathrate, 550 parts of purified water.

preparation Embodiment 1

[0031] Weigh 2 g of dried ginger and 9 g of scallions, add 13 times the amount of water, soak overnight, reflux extraction for 12 hours, collect the volatile oil, filter, collect the extract, dry the dregs at room temperature, and set aside. Weigh 5g of raspberry, 2g of donkey-hide gelatin, 2g of oyster medicinal materials, dried ginger and scallion dregs, soak in 15 times the amount of water for 2 hours, reflux extraction 3 times, 3 hours each time, and combine the extracts. Weigh 9g of honeysuckle and 5g of Polygonatum, add 10 times the amount of 65% ethanol to reflux for extraction for 3 times, each time for 1 hour, combine the extracts, and recover the ethanol until it has no alcohol smell. The three extracts were combined, centrifuged, concentrated at 70°C to a relative density of 1.33, and set aside. In the water phase, add 150g of propylene glycol and 10g of potassium hydroxide to 550g of purified water and adjust it in a 70°C water bath, then add 200g of glycerin and 4...

Embodiment 2

[0033] The required raw materials are calculated in parts by weight: 11.3 parts of honeysuckle, 7.5 parts of sealwort, 3.8 parts of dried ginger, 11.3 parts of scallion, 7.5 parts of raspberry, 3.8 parts of donkey-hide gelatin, 3.8 parts of oyster, 173 parts of propylene glycol, and 12 parts of potassium hydroxide , 210 parts of glycerin, 61 parts of azone, 231 parts of stearic acid, 115.5 parts of stearyl alcohol, 58 parts of glyceryl monostearate, 6 parts of methylparaben, 1 part of chlorhexidine acetate, 80 parts of volatile oil Tween 15 parts of clathrate, 580 parts of purified water.

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PUM

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Abstract

The invention provides a preparation method of ointment for improving skin itch of urogenital canal, belonging to the field of a preparation method of ointment for treating skin itch of urogenital canal. The ointment mainly consists of honeysuckle, rhizoma polygonati and the like. The preparation method of the ointment comprises the following steps of: soaking, carrying out reflux extraction, collecting and filtering, drying under low temperature and the like to prepare extracting solution, merging extracting solution, and concentrating by centrifuging to 1.33 of relative density to prepare ointment; preparing the matrix of the ointment by propylene glycol, potassium hydroxide and the like through a water phase process and an oil phase process; and adding essential oil tween 80 clathrate compound into the ointment and the matrix, and continuously stirring to be evenly mixed. The formula meets the principle of medicinal prescription formula, and the ointment achieves the functions of clearing away heat and toxic materials, dispelling wind and heat, killing parasites to relieve itching, nourishing yin, nourishing kidney and replenishing essence, securing essence and reducing urination in a complementary way; and the skin itch of urogenital canal caused by the bacterium, mould and trichomonas infection, the morbid leucorrhoea sickness and spermatorrhea, and the vaginal relaxation can be effectively alleviated. The ointment is small in side effects, directly acted on focus parts, and good in curative effect, and has the advantages of being quick in taking effect, high in cure rate, and convenient to use.

Description

technical field [0001] The invention belongs to the field of a preparation method of a medicinal ointment, in particular to a preparation method of a medicinal ointment which can be used for treating and improving skin pruritus of the genitourinary tract. Background technique [0002] Urogenital system infection is one of the common clinical infectious diseases, and the incidence rate of women is significantly higher than that of men. Pathogens often invade the urogenital system and cause urinary tract infections when the patient's immunity is weakened. People with urinary tract diseases, such as benign prostatic hyperplasia, neurocystitis, or patients who use urinary catheters, are more likely to suffer from recurrent urogenital infections, or suffer from genital infections caused by complicated urogenital infections. Skin pruritus. With the widespread use of broad-spectrum antibacterial drugs, drug-resistant strains continue to emerge, and the bacterial flora of infectio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/06A61P17/04A61P15/00A61K35/56A61K35/36A61K35/618
Inventor 张辉张洁孙佳明宫爽
Owner 吉林省东北亚生物科技有限公司
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