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Mouthwash with functions of antibiosis, antiphlogosis and deodorization, and preparation method and use thereof

An antibacterial, anti-inflammatory and mouthwash technology, which is applied to medical preparations containing active ingredients, antibacterial drugs, and the digestive system. It can solve the problems of oral mucosa peeling, large side effects of western medicine, and bacterial imbalance, so as to keep breath fresh. , good antibacterial effect, the effect of eliminating bad breath

Inactive Publication Date: 2013-02-27
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Most of the mouthwashes on the market are the combination of Chinese and Western medicines to prevent and treat oral diseases, and take Western medicines as the main functional components. Unfavorable and adverse drug reactions, severe cases may even cause flora imbalance, oral mucosa peeling and superimposed infection; and some oral care solutions containing Chinese herbal ingredients show their superiority in this respect

Method used

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  • Mouthwash with functions of antibiosis, antiphlogosis and deodorization, and preparation method and use thereof
  • Mouthwash with functions of antibiosis, antiphlogosis and deodorization, and preparation method and use thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0018] Embodiment 1 (percentage by weight)

[0019] Preparation of pomegranate peel extract:

[0020] First, weigh the pomegranate peel and crush it into a coarse powder, add 5-30 times the concentration of 50-70% ethanol to warm soak at a temperature of 30-70°C, extract 1-4 times, each time for 1-3 hours, filter, and the filtrate Recover ethanol under pressure, pass the liquid medicine through a macroporous resin chromatographic column, absorb for 3-12 hours, first elute with distilled water until the effluent is nearly colorless, then elute with 40-80% ethanol, collect until the eluate is colorless, Concentrate, remove ethanol at a temperature of 60°C, concentrate and dry under reduced pressure to obtain extract powder, pulverize, pass through a 60-140 mesh sieve, and set aside;

[0021] Mouthwash preparation:

[0022] a. Take 10% of roses and 10% of brocade lanterns, add 5 times the concentration of 40% ethanol to heat and reflux to extract twice, each time for 1 hour, fi...

Embodiment 2

[0024] Embodiment 2 (percentage by weight)

[0025]The preparation of pomegranate peel extract is carried out according to embodiment 1;

[0026] Mouthwash preparation:

[0027] a. Take 20% of roses and 20% of brocade lanterns, add 10 times the concentration of 60% ethanol to heat and reflux for extraction once, extract for 3 hours, filter, combine the filtrate to recover ethanol under reduced pressure, and concentrate to a relative density of 1.05-1.10 (Temperature 60 ℃) clear ointment, standby;

[0028] b. Dissolve 10% of the pomegranate peel extract in 10% propylene glycol as a humectant, stir evenly, add to the solution concentrated in step a, add sweetener cyclamate 0.8%, preservative potassium sorbate 0.5% and remaining Measure distilled water, fully stir and mix, let it stand for 24 hours, filter, pack, and fill, and the mouthwash product with antibacterial, anti-inflammatory and deodorizing properties can be obtained.

Embodiment 3

[0029] Embodiment 3 (percentage by weight)

[0030] The preparation of pomegranate peel extract is carried out according to embodiment 1;

[0031] Mouthwash preparation:

[0032] a. Take 15% of roses and 20% of brocade lanterns, add 15 times the concentration of 30% ethanol, heat and reflux extraction for 3 times, each time for 2 hours, filter, combine the filtrate to recover ethanol under reduced pressure, and concentrate to a relative density of 1.05- 1.10 (temperature 60°C) solution, for later use;

[0033] b. Dissolve 15% of pomegranate peel extract in 10% glycerin moisturizer, stir evenly, add to the solution concentrated in step a, add sweetener aspartame 0.6%, preservative sodium benzoate 0.3% and remaining Measure distilled water, fully stir and mix, let it stand for 24 hours, filter, pack, and fill, and the mouthwash product with antibacterial, anti-inflammatory and deodorizing properties can be obtained.

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Abstract

The invention discloses a mouthwash with functions of antibiosis, antiphlogosis and deodorization, and a preparation method of and the use of the mouthwash. The mouthwash comprises main raw materials, i.e. pericarpium granati extractive, flos rosae rugosae and calyx seu fructus physalis, and moisture preserving agent, sweetening agent, preservative and distilled water. The mouthwash can be used due to the combined action of various active ingredients, can form into the stoppage on the surfaces of teeth, can enable the bacterium to be hard to be attached onto the surfaces of the teeth, and can reduce the bacterium which is attached onto the surfaces of the teeth and causes the bacterial plaque, so that the oral hygiene can be kept, and the bad breath can be eliminated, therefore, the mouthwash can be used for preventing or treating the gingivitis, the periodontitis, the dental ulcer, and the oral and throat inflammation; and the bad breath can be eliminated, and the freshens breath can be kept, so that the mouthwash not only can be used for the adjuvant therapy of the oral inflammation, but also can be used for the daily oral health, and is free from any side effects after being used for a long time. When the mouthwash is used, due to the mouth washing action, the mouthwash not only is good for the motion of the muscles around the oral cavity, but also can promote the self-cleaning function of the oral cavity, thereby being the optimal choice for keeping the oral hygiene, and preventing and treating the oral infection.

Description

technical field [0001] The invention relates to an antibacterial, anti-inflammatory and deodorizing mouthwash and its preparation method and application, in particular to a liquid oral gargle with antibacterial, anti-inflammatory, deodorizing, easy to use and no toxic or side effects, its preparation method and application. Background technique [0002] The oral cavity is one of the ways for pathogenic microorganisms to invade the human body. The temperature, humidity and food residues in the oral cavity are suitable for the reproduction and growth of microorganisms. The interdental spaces and gingival grooves in the oral cavity are difficult to clean. These anatomical features are conducive to the growth of bacteria. Therefore, oral hygiene is very important to the health of the human body, especially for patients with high fever, postoperative disturbance of consciousness, and artificial respiration. Because they cannot eat orally, the secretion of saliva decreases, the mou...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K36/81A61Q11/00A61P31/04A61P1/02A61P11/04
Inventor 阿吉艾克拜尔·艾萨罗玉琴来海中马依努尔·拜克力
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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