Vector used for displaying antigenic epitope by using hepatitis B virus core particles, animal vaccine, and preparation method thereof
A technology of hepatitis B virus and core particles, applied in botany equipment and methods, biochemical equipment and methods, using vectors to introduce foreign genetic material, etc., can solve the problems of high production cost, high product price and inability to promote protein vaccines, etc. Achieve outstanding immune effect, reduce production cost, and be easy to construct
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[0041]The protective power of a vaccine lies in the strong immune response it induces in the body, and the strength of the body's immune response depends on the strength of the immune signal provided by the antigen. To improve the presentation of antigenic proteins to immune signals (epitopes), several possible technologies are worth exploring. The first technique is to create harmless mutants through genome manipulation, an idea that has been advocated and actually explored by many. However, this technical route also has two potential weaknesses: First, the work is relatively difficult. It is a very difficult task to find out the part where the pathogen can be deleted or mutated, so that the toxicity of the pathogen can be reduced or even disappeared without reducing the value-added ability of the pathogen. Difficult and long-term work; secondly, even if a harmless mutant strain is successfully developed, it is not a matter of once and for all, because after a long-term use o...
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