Method for preparing drug for treating pediatric esophageal achalasia
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology for achalasia and medicine is applied in the field of preparation of medicines for treating achalasia in children, and can solve the problems of lack of achalasia in children, high compliance with pain in children, and high recurrence rate, so as to reduce the types and dosage of medicines , Increase the burden on the liver and kidney, the effect of convenient taking
Inactive Publication Date: 2015-03-11
QINGDAO CENT HOSPITAL
View PDF0 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
However, the above-mentioned drugs are not suitable for use in pediatrics, so now more endoscopic balloon dilation is used, but dilation often requires multiple times to achieve relief, and the recurrence rate is high, and children with severe pain have poor compliance
Therefore, there is currently a lack of medical treatment drugs for children with achalasia.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0033] Example 1, the weight ratio of the raw materials: 10 parts of Muhe, 6 parts of kapok peel, 3 parts of Poria cocos, 6 parts of tangerine peel, 3 parts of Artemisia sylvestris, 6 parts of Trachelospermi Caulis, 6 parts of Pueraria lobata root, 6 parts of Aesculus vulgaris , 6 parts of loofah, 1 part of Gulixiang, 3 parts of Jiaoguya, 10 parts of Jiaoguya.
Embodiment 2
[0034] Example 2: Weight ratio of raw materials: 20 parts of Muhe, 10 parts of kapok peel, 6 parts of Poria cocos, 10 parts of tangerine peel, 6 parts of Artemisia japonica root, 10 parts of Trachelospermi Caulis, 10 parts of Pueraria lobata root, 10 parts of Aesculus vulgaris , 10 parts of loofah, 2 parts of Gulixiang, 6 parts of Jiao Malt, 20 parts of Jiao Gu Bu.
Embodiment 3
[0035] Example 3, the weight ratio of the raw materials: 30 parts of Muhe, 12 parts of kapok peel, 10 parts of Poria cocos, 12 parts of tangerine peel, 10 parts of Artemisia sylvestris, 12 parts of Trachelospermi Caulis, 12 parts of Pueraria lobata, 12 parts of Aesculus aesculus , 12 parts of loofah, 5 parts of Gurixiang, 10 parts of Jiao Malt, 25 parts of Jiao Gu Bu.
[0036] The Chinese medicines of Examples 1 to 3 can be prepared according to the following methods:
[0037] (1) Use steam distillation to extract the volatile oil from Pueraria lobata root, kapok bark and Artemisia japonica root powder, and mix them for later use after collection;
[0038] (2) Crush the coke grain and coke malt through a 150-mesh sieve to form a fine powder for later use;
[0039] (3) Muhe, Poria cocos, tangerine peel, Trachelospermi Caulis, loofah, Aesculus aesculus, and mulberry, mix well and add 10 times the amount of water, add water and decoct 2 times for 1 hour each time, combine the decoction a...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses a method for preparing a drug for treating pediatric esophageal achalasia. The drug is applied to the treatment of pediatric esophageal achalasia. The drug is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: fingerleaf rodgersflower rhizome, bombax malabaricum peel, paris polyphylla Sm., luffa cylindrica (L.) Roem., murraya jasminorage, poriacocos (Schw.) Wolf, citrus reticulata Blanco, rtemisia japonica Thunb., trachelospermum jasminoides (Lindl.) Lem., radix puerariae, hordeum vulgare L. and setaria italica Beauv.. The method comprises the following steps of: (1) extracting volatile oil from coarse powder of radix puerariae, bombax malabaricum peel and rtemisia japonica Thunb. for later use; (2) crushing setaria italica (L.) Beauv. into fine powder for later use; (3) carrying out water extraction and alcohol precipitation on fingerleaf rodgersflower rhizome, poriacocos (Schw.) Wolf, citrus reticulata Blanco, trachelospermum jasminoides (Lindl.) Lem., luffa cylindrica (L.) Roem., paris polyphylla Sm., murraya jasminorage and hordeum vulgare L., and drying so as to obtain a preliminary material; and (4) spraying the volatile oil into the preliminary material, adding the fine powder of setaria italica (L.) Beauv., uniformly mixing, sieving by using a 60-mesh sieve, and encapsulating. Proved by clinical trials, the drug prepared by the method has the characteristics of good treatment effect and high safety in the treatment of pediatric esophageal achalasia, so that the method is worthy of clinical application and popularization.
Description
Technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of a medicine for treating infantile achalasia. Background technique [0002] Esophageal achalasia (esophageal achalasia) is a disease of esophageal motility disorder, which refers to a disease in which there is no peristalsis in the esophageal body after swallowing, and achalasia of the cardiac sphincter is not good. It is characterized by relaxation disorder of the lower esophageal sphincter (LES) when swallowing, and lack of peristaltic contraction of the smooth muscle segment of the esophagus, which leads to functional obstruction of the esophagus. The cause of this disease is unclear. It may be related to toxins, nutritional deficiencies, genes and local inflammation. Clinical studies have found that mental concerns can aggravate the symptoms of children, consider whether the cortical nerve dysfunction caused by mental stimulation, leading to cen...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more