Cobalt-chromium alloy arterial stent system with full biodegrade medical coating

Abstract

The invention provides a cobalt-chromium alloy arterial stent system with a full biodegrade medical coating. The system comprises a transport system and a cobalt-chromium alloy arterial stent which has a full biodegrade medical coating and is sleeved on the transport system. The transport system comprises a push rod, a sacculus and a jacket respectively fixedly connected to both ends of the push rod, and a handle with a Luer joint. A cone-shaped hardened guide wire is arranged at the sacculus end of the push rod. The cobalt-chromium alloy arterial stent with the full biodegrade medical coating is sleeved on the sacculus. The system can avoid damage of the coating to the maximum extent, improve the retaining force between the bracket and the transport system greatly, prevent the probability that the bracket is out of load in the transport process, and reduce the clinical use risk, so that the problems of coronary artery stenosis and restenosis are effectively solved.

Description

[0001] This application is a branch of an invention patent application with application number 201010034532.9, titled: "Cobalt-chromium alloy arterial stent with fully biodegradable drug coating, stent system and its preparation method", and application date: January 21, 2010. case application. technical field [0002] The invention relates to a cobalt-chromium alloy arterial stent system with a fully biodegradable drug coating. Background technique [0003] Since the first bare metal stent Palmaz-Schatz in the United States was implanted into the human body in 1985, the restenosis rate of coronary vessels caused by simple balloon expansion is very high. Stent interventional therapy can successfully solve this problem and become the main method of clinical treatment. After that, the technology of interventional therapy experienced the era of development from bare metal stents to drug-eluting stents. Drug-eluting stents have been on the market for five years now. At home an...

AI Technical Summary

Problems solved by technology

[0004] In interventional therapy operations, when the stent is pressed until the diameter meets the requirements of the blood vessel, it is delivered to the thrombus lesion through a delivery system such as a balloon through a long blood vessel in the body. Due to technical problems, the stent and the delivery system are generally compressed. Grips are combined into a system for sales and use to facilitate clinical use. However, due to the fact that the coatings on the surface of traditional drug stents are mostly formed by unipolar coating technology, the adhesion is poor, which makes the combination between the coating and the metal platform of the stent weak and difficult. It is easy to cause coating damage during the crimping process, and it is easy to damage the coating when passing through narrow lesions, tortuous lesions or calcified lesions, resulting in uneven distribution of drugs, which directly affects the effectiveness and safety of drug stents; in addition, due to In the stent system, after the stent is sleeved on the balloon body of the delivery system, the tangential crimping technique is often used. In the tangential crimping scheme, the coating is inevitably damaged due to tangential friction on the surface, and due to the tangential pressure The limitation of gripping technology makes the indwelling force between the stent and the delivery system small, so that the stent is likely to be unloaded during the movement of the balloon with the balloon in the unexpanded state, and it is easy to cause the failure of the operation

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