Cobalt-chromium alloy arterial stent system with full biodegrade medical coating
A technology of drug coating and cobalt-chromium alloy, which is applied in stents, coatings, medical science, etc., can solve the problem of weak combination of coatings and stent metal platforms, affecting the effectiveness and safety of drug stents, and retention of stents and delivery systems To improve radial support force and X-ray visualization, reduce local inflammatory response and damage, and improve biological and mechanical properties
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Embodiment 1
[0041] Such as figure 1 As shown, a cobalt-chromium alloy arterial stent with a fully biodegradable drug coating, which includes a thin-walled hollow collar stent and a fully biodegradable drug coating coated on the stent, which is engraved and cut from a cobalt-chromium alloy L605 tube, The bracket includes a support rod 1 with six sine wave units in the circumferential direction and a connecting rod 2 connecting two adjacent support rods in the axial direction. Composition, the rib width of the circular arc connecting section 6 is less than or equal to the rib width of the straight rod 5; the crests 3 and troughs 4 of the sine wave units of the adjacent support rods 1 are respectively opposite, and the connecting rods 2 are arranged at intervals On the opposite two troughs 4 of two adjacent sine wave structures, and each trough 4 is provided with at most one connecting rod 2, the connecting rod 2 is composed of an "S"-shaped connecting section 7 and a straight rod connecting...
Embodiment 2
[0054] The difference between this embodiment and embodiment 1 is:
[0055] The rib width range of the arc connection section of the support rod is 0.0762mm, the rib width range of the straight rod is 0.0889mm, and the rib width range of the connecting rod is 0.07112mm.
[0056] The preparation method of the cobalt chromium alloy arterial stent with full biodegradable drug coating comprises the following steps:
[0057] (1) The cobalt-chromium alloy L605 pipe is electrochemically polished after laser engraving and cutting to prepare a thin-walled hollow collar bracket;
[0058] (2) Pretreatment is carried out to described support:
[0059] Carry out surface cleaning treatment: clean the surface of the bracket with purified water to remove fine particles and dust in the bracket processing process;
[0060] (3) Carry out secondary filtration and purification of radon gas, and then input it into the surface passivation treatment device, adjust the injection pressure to 0.15 bar...
Embodiment 3
[0065] The difference between this embodiment and embodiment 1 is:
[0066] The rib width range of the arc connection section of the support rod is 0.0762mm, the rib width range of the straight rod is 0.0762mm, and the rib width range of the connecting rod is 0.07mm.
[0067] The preparation method of the cobalt chromium alloy arterial stent with full biodegradable drug coating comprises the following steps:
[0068] (1) The cobalt-chromium alloy L605 pipe is electrochemically polished after laser engraving and cutting to prepare a thin-walled hollow collar bracket;
[0069] (2) Pretreatment is carried out to described support:
[0070] Carry out surface cleaning treatment: clean the surface of the bracket with purified water to remove fine particles and dust in the bracket processing process;
[0071] (3) Carry out secondary filtration and purification of nitrogen, and then input it into the surface passivation treatment device, adjust the injection pressure to 0.14 bar, th...
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