Traditional Chinese medicine for treating diabetes mellitus

A technology of diabetes and traditional Chinese medicine, which is applied in metabolic diseases, drug combinations, medical formulas, etc., can solve problems such as unsustainable effects, large side effects, and long-term medication, and achieve the effects of regulating lipid metabolism, reducing fasting blood sugar, and reducing proteinuria

Inactive Publication Date: 2013-08-07
WUHAN NUOBEI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effects of these western medicines cannot be sustained, and long-term medication is required, and the side effects are large.

Method used

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  • Traditional Chinese medicine for treating diabetes mellitus
  • Traditional Chinese medicine for treating diabetes mellitus
  • Traditional Chinese medicine for treating diabetes mellitus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A kind of Chinese medicine for treating diabetes, it is made of the raw materials of following weight ratio:

[0022] Danshen 50Kg Astragalus 50Kg Duckweed 30Kg Mori 10Kg

[0023] Coix seed 20Kg Pueraria 20Kg Hawthorn 10Kg.

[0024] The preparation method is as follows: crush the salvia miltiorrhiza and kudzu root into coarse powder, add 6 times of ethanol with a weight concentration of 80% by weight, reflux extraction for 3 times, each time for 1 hour, filter, combine the filtrates and concentrate under reduced pressure to form a Extract, filter residue, Astragalus membranaceus, Duckweed grass, Mori twig, Coix seed are added to 6 times of water by weight and decocted for 3 times, each time for 1 hour, filtered, the filtrate is combined with the above-mentioned extract, concentrated to a relative density of 1.25 The extract is made into granules by adding mannitol.

[0025] Dosage: Take before meals, three times a day, one bag each time (each serving is equivalent to ...

Embodiment 2

[0027] A kind of Chinese medicine for treating diabetes, it is made of the raw materials of following weight ratio:

[0028] Danshen 100Kg Astragalus 100Kg Duckweed 60Kg Mori 40Kg

[0029] Coix seed 50Kg Pueraria 50Kg Hawthorn 40Kg.

[0030] The preparation method is as follows: crush Danshen and Pueraria root into coarse powder, add 12 times of ethanol with a weight concentration of 50% by weight, reflux extraction once, extract for 3 hours, filter, combine the filtrates, and concentrate under reduced pressure to obtain a leaching solution with a relative density of 1.15. paste, filter residue, astragalus, duckweed grass, mulberry branch, and coix seed are added to 15 times the water by weight and decocted once, decocted for 3 hours, filtered, and the filtrate was combined with the above extract, concentrated into an extract with a relative density of 1.40. Paste, add microcrystalline cellulose and starch and compress into tablets.

[0031] Dosage: Take before meals, three ...

Embodiment 3

[0033] A kind of Chinese medicine for treating diabetes, it is made of the raw materials of following weight ratio:

[0034] Danshen 70Kg Astragalus 70Kg Duckweed 45Kg Mori 25Kg

[0035] Coix seed 35Kg Pueraria 35Kg Hawthorn 25Kg.

[0036] The preparation method is:

[0037] Grind Danshen and Pueraria root into coarse powder and add 8 times the weight concentration of 60% ethanol by weight, reflux extraction twice, each time for 2 hours, filter, combine the filtrate and concentrate under reduced pressure to obtain an extract with a relative density of 1.1, and filter residue Add astragalus, duckweed grass, mulberry branches, and coix seed together with 10 times the weight of water and decoct once for 3 hours, filter, and combine the filtrate with the above extract, and concentrate to obtain an extract with a relative density of 1.32 , adding an appropriate amount of starch to make granules, and filling them with capsules to make capsules.

[0038] Dosage: Take before meals,...

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Abstract

The invention discloses a traditional Chinese medicine for treating diabetes mellitus. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 50-100 parts of salvia miltiorrhiza, 50-100 parts of radix astragali, 30-60 parts of herba spirodelae, 10-40 parts of mulberry twig, 20-50 parts of semen coicis, 20-50 parts of kudzuvine root and 10-40 parts of hawthorn. Pharmacological experiments prove that the traditional Chinese medicine has the functions of obviously reducing fasting blood glucose and glycosylated haemoglobin of experimental rats with type 2 diabetes mellitus, reducing proteinuria of experimental rats with diabetic nephropathy and simultaneously regulating lipid metabolism of experimental rats with diabetic nephropathy. Clinical tests show that the traditional Chinese medicine has a total effective rate of 76.6% in treating patients with type 2 diabetes mellitus, does not have significant difference from metformin hydrochloride tablet control groups, but is superior to metformin hydrochloride tablets in improving clinical symptoms of type 2 diabetes mellitus and regulating lipid metabolism.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a traditional Chinese medicine for treating diabetes. Background technique [0002] Among the hypoglycemic drugs currently used clinically, all kinds of western medicines have certain limitations and serious adverse reactions, such as hypoglycemia, lactic acidosis, etc. Received hypoglycemic preparations. So far, there is no medicine that can completely cure diabetes, and western medicine can only control blood sugar. In contrast, traditional Chinese medicine has its own advantages and has a good development prospect. Some people believe that the hypoglycemic mechanism of traditional Chinese medicine is related to regulating the immune function of the body, improving the binding of insulin to its receptor, and enhancing the secretion of insulin by cells. This may open up a new way for Chinese medicine to treat diabetes by improving the body's immunity. [0003] Diabetic nephrop...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P3/10
Inventor 董莉霞徐晨昊曹瑜颖
Owner WUHAN NUOBEI PHARMA
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