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Preparation process of medicinal natural mirabilite intestinal-lavage drug powder

A manufacturing process and a natural technology, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, powder delivery, etc., can solve problems affecting intestinal peristalsis function, intestinal flora destruction, affecting colon cleansing effect, etc. Effect of causing electrolyte disturbance, uniform crystal size, and large crystal size

Inactive Publication Date: 2013-08-14
四川省川眉芒硝有限责任公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, colon lavage causes damage to the normal intestinal flora; patients who plan to undergo colonoscopy often have intestinal lesions, which will affect the normal peristaltic function of the intestinal tract and affect the effect of colon lavage

Method used

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  • Preparation process of medicinal natural mirabilite intestinal-lavage drug powder
  • Preparation process of medicinal natural mirabilite intestinal-lavage drug powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Dissolve natural mirabilite ore in tap water through polyvinylidene fluoride reverse osmosis membrane purification treatment to remove metal and non-metal ions in tap water, and the water flowing out from the reverse osmosis membrane is initially sterilized by laser with a wavelength of 26500 nanometers Treatment, the treatment time is 0.5s to purify the treated pure water to form raw nitric water with a concentration of 33.1%wt. After the nitric water is passed through a 321 stainless steel mesh to remove mechanical impurities, 0.5%wt heavy metal chelating agent EDTA is added for refining and purification treatment to obtain heavy metals Natural Glauber's salt aqueous solution with an ion impurity content of 0.3ppm. The Glauber's salt water is further sterilized by a laser with a wavelength of 26,500 nanometers. After a treatment time of 3 seconds, it is input into a continuous crystallization process system. In a continuous crystallization system The medium-refined nit...

Embodiment 2

[0041] Dissolve natural mirabilite ore in tap water through polyvinylidene fluoride reverse osmosis membrane purification treatment to remove metal and non-metal ions in tap water, and the water flowing out from the reverse osmosis membrane is initially sterilized by laser with a wavelength of 26500 nanometers Treatment, the treatment time is 3s to purify the treated pure water to form raw nitric water with a concentration of 22.9%wt. After the nitric water is passed through a 321 stainless steel mesh to remove mechanical impurities, 0.5%wt heavy metal chelating agent EDTA is added for refining and purification treatment to obtain heavy metal ions The natural thenardite aqueous solution with an impurity content of 0.1ppm is further sterilized by a laser with a wavelength of 26,500 nanometers. After the treatment time is 6s, it is input into a continuous crystallization process system. In a continuous crystallization system Refined nitric water exchanges heat with cold water at ...

Embodiment 3

[0045] Dissolve natural mirabilite ore in tap water through polyvinylidene fluoride reverse osmosis membrane purification treatment to remove metal and non-metal ions in tap water, and the water flowing out from the reverse osmosis membrane is initially sterilized by laser with a wavelength of 26500 nanometers Treatment, the treatment time is 2.6s to purify the treated pure water to form raw nitric water with a concentration of 33%wt. After the nitric water is passed through a 321 stainless steel mesh to remove mechanical impurities, 0.5%wt heavy metal chelating agent EDTA is added for refining and purification treatment to obtain heavy metals The natural thenardite aqueous solution with an ion impurity content of 0.2ppm is further sterilized by a laser with a wavelength of 26,500 nanometers. After a treatment time of 4 seconds, it is input into a continuous crystallization process system. In a continuous crystallization system The medium-refined nitric water exchanges heat wit...

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Abstract

The invention discloses a preparation process of medicinal natural mirabilite intestinal-lavage drug powder. The preparation process comprises the following steps of: treating natural mirabilite and adding other ancillary drugs; mixing and stirring uniformly by using alcohol as a dispersing agent; and evaporating to remove alcohol and residual moisture to obtain the intestinal-lavage drug containing medicinal natural mirabilite, wherein the weight ratio of the medicinal natural mirabilite mixture (dry basis) to fructose to glutamine to defoaming agent, composite active probiotics and 5-hydroxytryptamine receptor agonist is (87.39-94.76) to (5.0-2.0) to (2.0-4.0) to (0.2-0.6) to (1.0-3.0) to (0.01-0.04), so that the compound medicinal natural mirabilite intestinal-lavage drug for clinical enteroscopy or pre-operation intestinal preparation is finally obtained.

Description

Technical field: [0001] The invention belongs to the field of medical product processing. Background technique: [0002] Natural Glauber's salt, as a hypertonic solution, is often used for general catharsis. When it is used for colonoscopy or preoperative bowel cleansing preparation, its dose needs to be increased. At this time, not only the purity of natural Glauber's salt is high, the intestinal tract should be cleaned as thoroughly as possible, and the residual foam in the intestinal tract should be as little as possible; at the same time, the body's energy is guaranteed to prevent excessive apoptosis of intestinal epithelial cells due to intestinal lavage or fix obstacles. In addition, colon lavage causes damage to the normal intestinal flora; patients who are scheduled to undergo colonoscopy often have intestinal lesions, which will affect the normal peristaltic function of the intestinal tract and affect the effect of colon lavage. How to improve the taste when pati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/74A61K9/14A61K31/198A61K31/7004A61K33/04A61K35/741
Inventor 唐承薇易智慧胡兵黄志寅雍建国刘文良张大明苟兴无何兆丰李洪清邹华容龙旭杜文彬
Owner 四川省川眉芒硝有限责任公司