Compound teriflunomide transdermal patch for treating rheumatic arthritis, and preparation method thereof

A teriflunomide transdermal patch, teriflunomide transdermal technology, applied in the field of medicine, can solve the problems of poor transdermal permeability, limit transdermal application, etc., achieve good flexibility, improve transdermal penetration Overdose, long-lasting and stable effect
CN103520137AActive Publication Date: 2014-01-22SHENYANG PHARMA UNIVERSITY
2 Cites 3 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2014-01-22

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention discloses a compound teriflunomide transdermal patch for treating rheumatic arthritis, and a preparation method thereof, and belongs to the technical field of medicines. The compound teriflunomide transdermal patch for treating rheumatic arthritis is composed of a back lining layer, a medicine storage layer and an anti-adhesive layer, wherein the medicine storage layer is mainly prepared from the following raw material drugs in parts by weigh: 0.55-12 parts of teriflunomide, 0.55-12 parts of non-steroid anti-inflammatory drug, and 100 parts of pressure-sensitive adhesive. The compound teriflunomide transdermal patch can be used for avoiding irritation of an oral drug to gastrointestinal tracts, increasing the percutaneous permeability of the drug by an ion-pair technology, has a durable and stable curative effect, and can be used for treating rheumatic arthritis and pains caused by the same; if administration is interrupted, the patch can be peeled off, and the use is convenient; the patch is good in adhesion and flexibility.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a compound teriflunomide transdermal patch for treating rheumatoid arthritis and a preparation method thereof, belonging to the technical field of medicine. Background technique

[0002] Rheumatoid arthritis is a long-term chronic inflammation caused by an autoimmune disorder that causes the immune system to attack the joints. The disease is prone to occur in small joints such as hands, wrists, and feet, and recurs in a symmetrical distribution. This inflammation can cause irreversible joint damage to disability, and can lead to joint degenerative changes due to joint pain and wear, so it is considered a locally aggressive tumor. Epidemiological studies have shown that the prevalence of rheumatoid arthritis is about 0.28%, and it gradually increases with age. The prevalence of middle-aged and elderly people over 46 years old is the highest, and the prevalence of women is 6 times that of men. . In my country, the prevalence o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More