Calcium zinc gluconate oral solution
A technology of calcium zinc gluconate and oral solution, which is applied in the field of pharmaceutical preparations and compositions, can solve the problems of slow filtration speed, unbalanced and unstable solution system, and difficulty in taking by diabetics, so as to increase stability, reduce tooth decay and high The effect of blood sugar risk
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Embodiment 1
[0039]
[0040] Take an appropriate amount of purified water, heat to boiling for 30 minutes, add calcium gluconate, continue heating and stirring for 120 minutes, add zinc gluconate and lysine hydrochloride in turn, continue heating and stirring for 45 minutes, add lactic acid, sodium chloride, aspartame , acesulfame potassium, sodium benzoate, continue heating and stirring for 45 minutes, adjust the pH value to 4.0±0.10 with sodium hydroxide, and add purified water to the required amount, stir, heat and reflux for 15 minutes, cool to about 80°C, add essence, Stir for 10 minutes, when the liquid is cooled to below 30°C, filter through a 0.8um microporous membrane for the first time, and filter through a 0.22um microporous membrane for the second time, fill with 10ml PVC / PE bottle, plastic seal, and light Inspection, packaging.
Embodiment 2
[0042]
[0043] Take an appropriate amount of purified water, heat to boiling for 30 minutes, add calcium gluconate, continue heating and stirring for 120 minutes, add zinc gluconate and lysine hydrochloride in turn, continue heating and stirring for 45 minutes, add lactic acid, sodium chloride, aspartame , acesulfame potassium, sodium benzoate, continue heating and stirring for 45 minutes, adjust the pH value to 4.0±0.10 with sodium hydroxide, and add purified water to the required amount, stir, heat and reflux for 15 minutes, cool to about 80°C, add essence, Stir for 10 minutes, when the liquid is cooled to below 30°C, filter through a 0.8um microporous membrane for the first time, and filter through a 0.22um microporous membrane for the second time, fill with 10ml PVC / PE bottle, plastic seal, and light Inspection, packaging.
Embodiment 3
[0045]
[0046] Take an appropriate amount of purified water, heat to boiling for 30 minutes, add calcium gluconate, continue heating and stirring for 120 minutes, add zinc gluconate and lysine hydrochloride in turn, continue heating and stirring for 45 minutes, add lactic acid, sodium chloride, aspartame , acesulfame potassium, sodium benzoate, continue heating and stirring for 45 minutes, adjust the pH value to 4.0±0.10 with sodium hydroxide, and add purified water to the required amount, stir, heat and reflux for 15 minutes, cool to about 80°C, add essence, Stir for 10 minutes, when the liquid is cooled to below 30°C, filter through a 0.8um microporous membrane for the first time, and filter through a 0.22um microporous membrane for the second time, fill with 10ml PVC / PE bottle, plastic seal, and light Inspection, packaging.
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