Veterinary antiviral traditional Chinese medicine Ziqi effervescent granules and preparation method thereof

Abstract

The invention belongs to the technical field of traditional Chinese medicinal veterinary drugs, and discloses a veterinary antiviral traditional Chinese medicine Ziqi effervescent granules and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 30-50 parts of Echinacea purpurea, 30-45 parts of Astragalus membranaceus, 10-25 parts of Scutellaria baicalensis, 10-25 parts of Flos Lonicerae, and 5-15 parts of Forsythia suspense. The medicine is used for preventing and treating Newcastle disease and infectious bursal disease of poultry, and effectively inhibiting spread and diffusion of bacterial and viral diseases of livestock and poultry. The medicine has medicament and nutritional agent dual functions, and can be used as an immunopotentiator and immunostimulant to enhance the immunity of livestock and poultry and improve the disease resistance.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese veterinary medicine, and in particular relates to a veterinary antiviral traditional Chinese medicine Ziqi effervescent granule and a preparation method thereof. Background technique [0002] Newcastle disease (ND) is an acute, febrile, septic and highly contagious infectious disease of poultry caused by Newcastle disease virus. Young chickens are most susceptible to infection, and adult chickens are less susceptible. Sick chickens are the main source of infection for this disease. The virus can invade the body through the digestive tract, respiratory tract, conjunctiva, injured skin and cloacal mucosa. Clinically, it is characterized by high fever, dyspnea, diarrhea, nervous disorders, and mucosal and serosal hemorrhage. Chicken disease is mostly acute, subacute and chronic, with high morbidity and mortality, and is a major infectious disease that endangers the poultry industry. [...

AI Technical Summary

Problems solved by technology

[0003] At present, there are the following problems in the prevention and treatment of chicken Newcastle disease: First, the pathogenic factors are complex, the incubation period is 2 to 15 days or longer, and there are mixed infections such as viruses, bacteria, and mycoplasma, which cannot be effectively prevented by vaccines alone.

Second, due to the extensive use of antibiotics and chemical antibacterial drugs, pathogenic microorganisms have developed a wide range of drug resistance, which has led to a continuous decline in the therapeutic effect. Clinically, the dose has to be increased and the administration time has been prolonged, which greatly increases the difficulty and cost of treatment; The third is that amantadine, ribavirin and other antiviral drugs are widely banned, and it is difficult to find specific drugs that are more symptomatic in clinical practice. The mortality rate of fast-onset diseased chickens is high, and the chickens that survived have paroxysmal convulsions, muscle tremors, and neck torsion. , opisthotonus and other neurological symptoms, the edible value is significantly reduced, and even eliminated

Fourth, serum treatment also has certain risks, which may bring about the occurrence of other diseases

However, there are still the following problems: one is that the traditional Chinese medicines for the treatment of Newcastle disease are mainly in the form of oral administration or mixed powder formulations, which cannot be administered with mixed drinks, and it is inconvenient to use in modern intensive farms; The clinical trials cannot prove its effectiveness from the perspective of modern epidemiology; the third is that its mechanism of action has not been clarified from the perspective of modern pharmacology

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