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Preparation of high-activity Maca extract as well as compound preparation formula and application of Maca extract

A technology of maca extract and compound preparation, which is applied in the directions of drug combination, pharmaceutical formula, inorganic active ingredients, etc., can solve the problems of low content, increase the cost of use by consumers, and the effect is difficult to be obvious, and improve the selectivity and yield. , Increase the sample throughput and improve the effect of uniformity

Inactive Publication Date: 2015-01-07
KUNMING GOODKWANG HEALTH CARE FOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Although maca is a natural plant rich in various nutrients, it is only a new resource food after all, and the content of functional ingredients such as macaene, magaamide, and glucosinolate that really work is very low. Such a "big and complete" composition and function, the result is that it is impossible to confirm the structure and accurate quantification of the active ingredients that the product really works. The effect is difficult to be obvious in the short term. In particular, to achieve the most basic expected effect, you must take at least 15-25 grams of maca dry powder every day. It runs counter to the wish of "fast and effective", and at the same time, it also greatly increases the cost of use for consumers

Method used

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  • Preparation of high-activity Maca extract as well as compound preparation formula and application of Maca extract
  • Preparation of high-activity Maca extract as well as compound preparation formula and application of Maca extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Example 1 Take dry maca tablets and wet them evenly by spraying with water to keep the moisture content at about 20%, and leave for 3 hours. Using liquid nitrogen as the cooling liquid, use a cryogenic pulverizer to pulverize, control the temperature at -5°C, and crush the particle size to 300-400 mesh. Put the maca powder into a microwave extractor, and use a mixture of petroleum ether (boiling range 60~90℃) and ethanol as the extract. Among them, petroleum ether accounts for 65% of the total volume of the mixed solvent, and the fine maca powder is mixed with The solid-liquid ratio of the solvent is 1:10, stirring, the mixture is preheated to 50°C, and the temperature is maintained for 1.5 hours. Perform microwave extraction on the preheated mixture, set a power of 2000W, and use microwaves with a wavelength of 2450 Hz and 915 Hz to heat them for 5 minutes with sufficient stirring. The solid-liquid separation was performed with a ceramic filter while it was hot, and th...

Embodiment 2

[0045] Example 2 The maca dry tablets were evenly moistened with water by a spray method to keep the moisture content at about 25% and left for 4 hours. Using liquid nitrogen as the cooling liquid, use a low-temperature pulverizer for pulverization, control the temperature at -10°C, and the crushing particle size is 300-400 mesh. Put the maca powder into the microwave extractor, and use the mixture of petroleum ether (boiling range 60~90℃) and ethanol as the extraction liquid. Among them, petroleum ether accounts for 75% of the total volume of the mixed solvent, and the fine maca powder is mixed with The solid-liquid ratio of the solvent is 1:15, stirring, the mixture is preheated to 60°C, and the temperature is maintained for 2 hours. Microwave extraction was performed on the preheated mixture. The power was set to 3500W, the wavelengths were 2450Hz and 915Hz, and the microwaves were heated at 2450Hz and 915Hz for 10 minutes respectively under sufficient stirring. Discharging...

Embodiment 3

[0049] Example 3 In a clean room, put 330g maca extract, 20g salidroside, 150g taurine, 42.3g zinc acetate into 457.7g olive oil, heat and stir at 40℃, mix evenly, and prepare 1000g of the mixture is made into soft capsules.

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PUM

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Abstract

The invention discloses preparation of a high-activity Maca extract as well as a compound preparation formula and an application of the Maca extract. Each 1,000 g of the compound preparation comprises components as follows: 300-500 g of Maca extract, 10-30 g of salidroside, 100-250 g of taurine, 10-20 g of zinc elements, 0-60 g of coenzyme Q10 and the balance of solid or liquid auxiliaries. The compound can be processed into soft capsules, hard capsules or tablets. The Maca extract in the formula adopts dried Maca as a raw material and is prepared through spraying moisturizing, low-temperature grinding, microwave extraction by a petroleum ether / ethanol mixed solvent, solid-liquid separation, spraying drying and grinding sequentially; the extract contains 10%-12% of high-activity Macaenes, Macamides, glucosinolate and benzyl isothiocyanate; and a healthcare product produced with the formula has remarkable prevention and treatment effects on fatigable crowds and crowds with sexual dysfunction.

Description

Technical field [0001] The invention relates to the preparation of maca extract and the formula of its health product. Specifically, it relates to the preparation of highly active maca extract and its compound formulation formula and application. Background technique [0002] As the pace of life accelerates, people are faced with various pressures from work, life and family. Many people have been in a state of dizziness and exhaustion for a long time, showing dizziness and inability to concentrate. Difficulty in thinking, insomnia, forgetfulness, decreased libido, error-proneness, decreased work efficiency, etc. This is the specific manifestation of fatigue syndrome. If this fatigue sub-health state is not resolved and restored in time, it will induce various acute or chronic diseases, such as Cardiovascular and cerebrovascular diseases, death from overwork, sexual reproductive disorders (such as infertility, prostatitis, sexual asthenia, menopausal syndrome, etc.), insomnia and...

Claims

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Application Information

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IPC IPC(8): A61K36/31A61P39/00A61P15/00A61K31/7032A61K31/185A61K31/122A61K33/30
CPCA61K9/4858A61K9/4866A61K31/122A61K31/185A61K31/7032A61K33/30A61K36/31A61K2236/30A61K2236/39A61K2236/53A61K2300/00
Inventor 朱洪友雷泽张爱华
Owner KUNMING GOODKWANG HEALTH CARE FOOD
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