Application of composition of garlic total polysaccharide and sulfur-containing amino acid in resisting skin desquamation and itching

Abstract

The invention provides a composition of garlic total polysaccharide and sulfur-containing amino acid. The composition mainly comprises garlic water-soluble macromolecule effective components, has good effects on inhibiting scurf and relieving itching, is applicable to various skin desquamation, scurf, ichthyosis, and various skin itching symptoms, and has the functions of supporting right, dispelling evil, and reducing toxicity. The composition has wide application prospects, and can be prepared into medicaments or cosmetics for preventing and treating desquamation and relieving itching with significant curative effect and less toxic or side effects. The invention also provides a method for preparing the composition, which comprises: extracting garlics, performing centrifugation or filtration to remove superfluous impurities so as to obtain the composition meeting the requirements; or purifying the extract through an ion exchange chromatographic column to obtain garlic sulfur-containing amino acid; then performing concentration and alcohol precipitation of an eluate to obtain garlic total polysaccharide, or adding the extract into an organic solvent such as alcohol and the like, and performing precipitation to obtain garlic polysaccharide; finally combining the garlic sulfur-containing amino acid with the polysaccharide according to a weight ratio to obtain the composition meeting the requirements. The preparation method is simple in operation, low in cost, controllable in quality, and suitable for industrialization.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a composition comprising garlic polysaccharide and garlic sulfur-containing amino acid water-soluble components, in particular, relates to the preparation of a composition comprising garlic total polysaccharide and garlic total amino acid for preventing skin desquamation and Application in pruritus medicine and cosmetics, and preparation method of the composition. Background technique [0002] Skin desquamation (desquamation) is common in the continuous keratinization and renewal of the normal skin surface, but because of the small amount, it is generally not easy to detect. A large amount of skin desquamation can be seen in pathological state. Rice bran desquamation is common in measles; flaky desquamation is common in scarlet fever; and silvery white scaly desquamation is common in psoriasis. [0003] The epidermis of normal skin is cornified stratified squamous epithelium that is resis...

AI Technical Summary

Problems solved by technology

[0006] Chinese patent 02138752 is a kind of external medicine for relieving itching, relieving pain and reducing swelling made by pure traditional Chinese medicine. It is composed of sulfur, realgar, garlic, Sichuan pepper, flavescens, and basil, and its components are sulfur: realgar: garlic: Sichuan pepper: Sophora flavescens: Molecular ratio of 1: 0.5-5: 0.2-4: 0.2-5: 1-4: 1-5 It provides a kind of medicine suitable for all kinds of people, and has a special effect on the treatment of mosquitoes and other poisonous insect bites The patent is only a compound preparation containing garlic, and no relevant research has been conducted on the active ingredients and efficacy of garlic

[0009] Literature and patent reports are all about garlic extract, the preparation method and efficacy of allicin, and do not involve the application of garlic polysaccharides and sulfur-containing amino acids; the above-mentioned patents only mention that garlic extract has an antipruritic effect, but do not Elaborate whether garlic polysaccharides and sulfur-containing amino acids have antipruritic and anti-dandruff effects, and did not optimize the ratio of the amount of sulfur-containing amino acids and garlic polysaccharides, it is only a simple crude extract; therefore, the existing The development and application of water-soluble components such as garlic polysaccharides and sulfur-containing amino acids in the technology is not deep and comprehensive enough, and it is necessary to strengthen the research on the application of garlic water-soluble components in the field of desquamation prevention and antipruritic application

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