Bioactive glass ceramic and preparation method thereof

Abstract

The invention discloses a bioactive glass ceramic and a preparation method thereof. The ceramic comprises the following raw materials in parts by weight: 80-100 parts of sodium oxide, 10-20 parts of calcium oxide, 4-10 parts of phosphoric anhydride, 5-15 parts of potassium fluoride, 10-15 parts of potassium oxide, 20-30 parts of silicon dioxide, 10-40 parts of zinc oxide and 5-9 parts of polybutylene succinate. The preparation method comprises the following steps: putting sodium oxide, calcium oxide, phosphoric anhydride, potassium fluoride, potassium oxide, silicon dioxide, zinc oxide and polybutylene succinate in a crucible and maintaining the temperature at 1400-1800 DEG C for 1-2 hours; drastically cooling the crucible to form a fusion cake and crushing the fusion cake into glass powder; melting the glass powder at 1000-1200 DEG C in the crucible and naturally cooling the melted glass powder so that the bioactive glass ceramic is obtained. The bioactive glass ceramic is capable of actively participating in biological reactions so as to induce the contacted bone tissues to grow around the bioactive glass ceramic, so that a continuous bone material is formed.

Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a bioactive glass ceramic and a preparation method thereof. Background technique

[0002] Bone defects have always been a medical problem. At present, the ideal method is autologous or allogeneic bone grafting, and autologous bone grafting is widely regarded as the "gold standard" for measuring bone graft fusion. Although autologous bone grafting has many advantages, such as adapting to the regeneration of surrounding bone tissue, there are still some disadvantages, such as limited donors for autologous bone grafting, secondary trauma, increased surgical difficulty, and a certain failure rate. Allograft bone sometimes cannot stimulate osteogenesis, and often induces adverse reactions. Research on new bone substitute products has become a common problem faced by medical workers and material workers. The new type of glass-ceramic can replace bone tissue to a certain extent, but i...