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Medicinal composition for treating damp-heat abundant type trachoma and preparation method thereof

A kind of combination and abundant technology, which is applied in the direction of drug combination, pharmaceutical formula, active ingredients of hydroxyl compounds, etc., can solve the problems of high toxic and side effects, easy recurrence, and dependence, and achieve no toxic and side effects, short treatment period, Efficient and high effect

Inactive Publication Date: 2015-10-07
吴强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Western medicine has a lot of toxic and side effects, which can easily cause peripheral neuritis, central nervous system poisoning, liver and kidney damage, liver and kidney toxicity, gastrointestinal reactions, etc. Good for treatment, and often dependent

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0067] When the dosage form of the pharmaceutical composition is a granule, its preparation method comprises the following steps:

[0068] The first step is to mix the raw materials of the pharmaceutical composition according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% that is 4 to 8 times that of the mixture, heat to boiling and reflux for 3 to 5 hours, and filter. Use the percolation method to percolate slowly at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C. Spray drying, the air inlet temperature of the spray dryer is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0069] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 40-50° C. to obt...

Embodiment 1

[0077] Example 1 Granules

[0078] The production process of the granules of the present invention is as follows: take 220g of Viola, 160g of Fangfeng, 250g of Sophora flavescens, 400g of Scutellaria barbata, 250g of Borneolum, 360g of Asarum, 150g of Passepartout, 260g of Qumai, 240g of Cimicifuga, 320g of Hollyhock Leaf Dioscorea , 400g of cicada slough, 350g of duckweed, 200g of delphinium, 340g of akebia, 150g of capillary, 210g of burdock, 440g of woody, 200g of medlar, 220g of alfalfa, 30g of golden stone, 400g of anemarrhena, native cow Knee 180g and psyllium 260g;

[0079] The first step is to mix the raw materials of the pharmaceutical composition according to the stated ratio, add 90% ethanol with an alcohol concentration 6 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use the percolation method to Slowly percolate at a speed of 1.5ml, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.07Mpa to a...

Embodiment 2

[0081] Example 2 Smear

[0082] The preparation process of the smear of the present invention is as follows: take 300g of Viola chinensis, 140g of Fangfeng, 220g of Sophora flavescens, 360g of Banzhilian, 200g of Borneolum, 330g of Asarum, 180g of Passepartout, 270g of Qumai, 240g of Cimicifuga, 300g of Hollyhock Leaf Dioscorea , 420g cicada slough, 300g duckweed, 210g delphinium, 330g akebia, 170g capillary, 380g burdock, 450g woody, 200g medlar, 220g alfalfa, 30g golden stone, 420g anemarrhena, native cow Knee 160g and psyllium 240g;

[0083] The first step: first crush the raw medicinal materials into coarse powder, then further crush, pass through a 200-mesh sieve, so that the amount of fine powder passing through the 200-mesh sieve reaches at least 60%, and collect the fine powder passing through the 200-mesh sieve to obtain a fine powder a; The second step: Put the coarse powder that cannot pass through the 200-mesh sieve into a multi-functional extraction tank for extr...

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Abstract

The invention discloses a medicinal composition for treating damp-heat abundant type trachoma and a preparation method thereof. The medicinal composition is prepared from the following raw medicinal materials: viola yedoensis makino, divaricate saposhnikovia root, lightyellow sophora root, barbed skullcap herb, herb of laurusleaf jasmine, borneol, manchurian wildginger herb, beautiful sweetgum fruit, herb of lilac pink, largetrifoliolious bugbane rhizome, ambergris, rhizome of hollyhock-like yam, cicada slough, clinopodium chinense, common ducksmeat herb, saccatespur larkspur, akebia stem, capillary wormwood herb, great burdock achene, costus root, barbary wolfberry fruit, talc, rectanglesickle medick, vermiculite, common anemarrhena rhizome, chinaroot greenbier rhizome, root of twotooth achyranthes and plantain seed. The medicinal composition disclosed by the invention has the beneficial effects of having the effects of dispelling wind, clearing spleen and eliminating dampness, having functions of promoting dieresis, discharging fire and improving eyesight, being mainly used for treating the damp-heat abundant type trachoma, and having the advantages of quick action, high effective rate, definite curative effect, short course of treatment, no toxic or side effects, low price and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating damp-heat excess trachoma and a preparation method thereof. Background technique [0002] Trachoma is a chronic conjunctival keratitis caused by Chlamydia trachomatis, which is one of the blinding eye diseases. It is called trachoma because it forms a rough and uneven appearance on the surface of the palpebral conjunctiva, resembling sand grains. In the early stage of the disease process, the conjunctiva infiltrates, such as papillae and follicular hyperplasia, and corneal pannus occurs at the same time; in the late stage, the scarring of the affected palpebral conjunctiva results in entropion deformity and aggravated corneal damage, which can seriously affect vision and even cause blindness. [0003] Clinical manifestations of trachoma: The incubation period is about 5 to 12 days. Usually affects both eyes. Mostl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/90A61P27/02A61K33/00A61K31/045A61K35/64A61K33/12A61K35/38
Inventor 吴强
Owner 吴强
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