Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A system and method for synthesizing cyclohexanone oxime in a microreactor

A technology of cyclohexanone oxime and micro-reactor, which is applied in oxime preparation, organic chemistry, etc., can solve the problems of large material retention, local hot spots, poor effect, etc., and achieve improved controllability and safety, and material retention small effect

Active Publication Date: 2017-06-30
TSINGHUA UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some problems in this reaction device: firstly, the volume of the slurry bed reactor is large, and the effect of mechanical stirring is poor, which easily leads to uneven distribution of reactant concentration and local hot spots; secondly, the stagnation of materials in the reactor is large, Once a large amount of hydrogen peroxide is decomposed, it will cause a safety accident

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A system and method for synthesizing cyclohexanone oxime in a microreactor
  • A system and method for synthesizing cyclohexanone oxime in a microreactor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Equipment parameters: the first micro-mixer 1 is a micro-mesh mixer, and the second micro-mixer 2 is a T-shaped micro-channel mixer. Among them, the micro-sieve mixer contains 20 micro-sieves with a diameter of 0.05 mm, and the hydraulic diameter of the T-shaped micro-channel is 0.1 mm.

[0027] Operating conditions: the concentration of titanium silicon molecular sieve in raw material A is 0.1wt%, the concentration of ammonia is 1wt%, and the molar ratio of ammonia to cyclohexanone is 2.5. The concentration of hydrogen peroxide in raw material B is 1 wt%, and the molar ratio of hydrogen peroxide to cyclohexanone is 1. The reaction temperature is 90° C., the reaction pressure is 0.2 MPa, and the reaction residence time is 20 minutes.

[0028] Reaction result: the conversion rate of cyclohexanone is 98.2%, and the selectivity of cyclohexanone oxime is 99.8%.

Embodiment 2

[0030] Equipment parameters: the first micro-mixer 1 is a micro-mesh mixer, and the second micro-mixer 2 is a Y-shaped micro-channel mixer. Among them, the micro-sieve mixer contains a micro-sieve with a diameter of 5mm, and the hydraulic diameter of the Y-shaped microchannel is 6mm.

[0031] Operating conditions: the concentration of titanium silicon molecular sieve in raw material A is 10wt%, the concentration of ammonia is 15wt%, and the molar ratio of ammonia and cyclohexanone is 1.5. The concentration of hydrogen peroxide in raw material B is 10wt%, and the molar ratio of hydrogen peroxide to cyclohexanone is 1.5. The reaction temperature is 60° C., the reaction pressure is 0.5 MPa, and the reaction residence time is 3 minutes.

[0032] Reaction result: the conversion rate of cyclohexanone is 99.8%, and the selectivity of cyclohexanone oxime is 99.0%.

Embodiment 3

[0034] Equipment parameters: the first micro-mixer 1 is a micro-mesh mixer, and the second micro-mixer 2 is a cross-shaped micro-channel mixer. Wherein, the micro-sieve mixer contains two micro-sieves with a diameter of 4mm, and the hydraulic diameter of the cross-shaped microchannel is 4mm.

[0035] Operating conditions: the concentration of titanium silicon molecular sieve in raw material A is 8wt%, the concentration of ammonia is 12wt%, and the molar ratio of ammonia and cyclohexanone is 2. The concentration of hydrogen peroxide in raw material B is 8wt%, and the molar ratio of hydrogen peroxide to cyclohexanone is 1.5. The reaction temperature is 70° C., the reaction pressure is 0.4 MPa, and the reaction residence time is 5 min.

[0036] Reaction result: the conversion rate of cyclohexanone is 99.6%, and the selectivity of cyclohexanone oxime is 99.5%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
diameteraaaaaaaaaa
diameteraaaaaaaaaa
Login to View More

Abstract

The invention discloses a system and a method for synthesizing cyclohexanone oxime with a microreactor, belonging to the field of chemical reaction engineering. The system is composed of a first micro-mixer, a second micro-mixer, a reaction pipeline with a heat exchange jacket and a back pressure valve connected in series. First, use the first micro-mixer to mix the slurry containing titanium-silicon molecular sieve and ammonia with hydrogen peroxide solution, and then use the second micro-mixer to disperse cyclohexanone into the mixed slurry to initiate the ammoximation reaction, and finally in the reaction The reaction process is completed in the pipeline. The system can achieve high conversion rate (>99%) and high selectivity (>99%) within a reaction time of 0.5min to 20min. The amount of stagnation of materials in the micro-reaction system is small, which improves the controllability and safety of the ammoximation reaction.

Description

technical field [0001] The invention belongs to the field of chemical reaction engineering, and in particular relates to a system and a method for synthesizing cyclohexanone oxime with a microreactor. Background technique [0002] Caprolactam is an important basic organic chemical used in the synthesis of nylon 6 fibers and nylon 6 engineering plastics. It is widely used in textiles, automobiles, electronics and other industries, and plays an important role in the development of the national economy. With the rapid development of my country's economy, the demand for caprolactam is increasing year by year. In 2013, the apparent consumption of caprolactam in my country has reached 1.5 million tons. The development and utilization of caprolactam in my country has a very broad prospect. Cyclohexanone oxime is a key intermediate in the production of caprolactam from cyclohexane. At present, about 80% of caprolactam in the world is obtained through Beckmann rearrangement of cyc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07C251/44C07C249/04
Inventor 骆广生董晨王凯张吉松
Owner TSINGHUA UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com