Biological preparation for preventing influenza and preparation method of biological preparation

Abstract

The invention relates to a biological preparation for preventing influenza and a preparation method of the biological preparation. The method comprises the following steps: weighing the following raw materials in percentage by weight: 20%-30% of echinacea, 20%-30% of houttuynia cordata, 5%-25% of citron day-lily, 10%-20% of wild chrysanthemum flower and 10%-20% of rhodiola rosea; adding purified water which is 6-10 times of weight of the raw materials, and stirring and mixing the raw materials; carrying out reflux extraction, centrifugally separating an extract liquid, and intercepting the obtained clear liquid in an ultrafiltration membrane to obtain a residual liquid A and dialysate; putting the dialysate into a macroporous resin HPD-100 chromatographic column for chromatography, and eluting with a 30%-80% ethanol solution to obtain an eluant B; mixing the residual liquid A with the eluant B, and carrying out vacuum concentration at 60-80 DEG C to obtain a concentrated liquid; and putting the concentrated liquid into a vacuum drying oven to obtain a dried product, namely the preparation, under the conditions that the temperature is 65-85 DEG C and the vacuum degree is 500-800Pa. Compared with the prior art, the biological preparation has the advantages that the immunity of the organism is enhanced; the cellular and humoral immunity is improved; the influenza virus is directly inactivated; fusion of an endosome / lysosomal membrane is suppressed; and influenza virus replication is reduced.

Description

technical field [0001] The invention relates to a cold medicine, in particular to a biological preparation capable of preventing and treating influenza and a preparation method thereof. Background technique [0002] Influenza is an acute respiratory infectious disease caused by influenza virus, referred to as "flu", and is one of the important diseases that seriously affect human health. It has the characteristics of high morbidity, high infectivity and high death toll. Whether it is the epidemic of SARS in 2003, the spread of avian influenza virus, or the large-scale global epidemic of influenza A in 2009, it has caused great harm to human beings and society. [0003] Because influenza virus is easy to mutate, it is difficult for chemical drugs and influenza virus vaccines to exert the best therapeutic and preventive effects. In the practice of influenza prevention and treatment, traditional Chinese medicine has continuously innovated methods, accumulated experience, and ...

AI Technical Summary

Problems solved by technology

[0005] The use of Chinese herbal medicines to prevent and treat influenza virus has the characteristics of few side effects, abundant drug sources, low price, and many action targets. It has unique advantages and broad development prospects. For example, patent application 200810054766.2 discloses a Chinese medicine preparation, which consists of the following parts by weight Drugs prepared from raw materials: 1 part of Su Ye, 3 parts of notopterygium, 10 parts of mint, 3 parts of Chuanqiong, 10 parts of Fangfeng, 3 parts of Angelica dahurica, 10 parts of Nepeta, 3 parts of raw land, 12 parts of double flower, 3 parts of tempeh 30 parts of Radix Scutellariae, 3 parts of Peucedanum, 10 parts of Atractylodes Rhizome, 3 parts of Bupleurum, 10 parts of Licorice, 10 parts of Houttuynia, 3 parts of Forsythia, 10 parts of Campanulaceae, 10 parts of Huoxiang, the traditional Chinese medicine preparation for treating colds It is a traditional Chinese medicine preparation that can comprehensively treat colds, but it has many components, and the effect is slow and the effect is not good

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