Medicinal composition for treating atherosclerosis and preparation method of medicinal composition

An atherosclerosis and composition technology, which is applied in the field of medicine, can solve the problems of obvious adverse reactions, large toxic and side effects, strong irritation and dependence, etc., achieves alleviation of the formation of atherosclerotic plaques, and a simple preparation method. , the effect of alleviating side effects

Inactive Publication Date: 2016-01-20
钟霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the drug is used in combination, especially when the dose is large, the occurrence of abnormal liver function and myolysis will increase significantly, and the adverse reactions will be more significant.
Although Western medicines are effective in treating diseases, they have relatively large toxic and side effects, strong irritation and dependence, and atherosclerosis cannot be eradicated.
[0007] The efficacy of traditional Chinese medicine in treating atherosclerosis has been prov

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A pharmaceutical composition for treating atherosclerosis, which is made of the following raw materials in parts by weight: 1.2 parts of clofibrate, 0.2 parts of probucol, and 100 parts of a Chinese medicine composition; the Chinese medicine composition is made of the following parts by weight 15 parts of Salvia miltiorrhiza, 10 parts of curcuma, 12 parts of kudzu root, 15 parts of Sophora japonica, 8 parts of tangerine peel, 18 parts of Hedyotis diffusa, 15 parts of Hovenia dulcis, 10 parts of fairy spleen, 22 parts of Atractylodes macrocephala, snake 9 parts of bed seeds, 14 parts of Polygala, 8 parts of Gynostemma, 25 parts of Polygonum cuspidatum, and 12 parts of Puhuang.

[0045] The preparation method of the pharmaceutical composition for treating atherosclerosis comprises the following steps:

[0046] (1) Extraction of traditional Chinese medicine components: add water to the raw materials of traditional Chinese medicines except kudzu root, Polygonum cuspidatum, ...

Embodiment 2

[0051] A pharmaceutical composition for treating atherosclerosis, which is made of the following raw materials in parts by weight: 1 part of bezafibrate, 0.1 part of probucol, and 150 parts of a traditional Chinese medicine composition; 13 parts of Salvia miltiorrhiza, 8 parts of curcuma, 12 parts of kudzu root, 10 parts of Sophora japonica, 8 parts of tangerine peel, 15 parts of Hedyotis diffusa, 14 parts of Hovenia dulcis, 8 parts of fairy spleen, 22 parts of Atractylodes macrocephala, Cnidium 6 parts, Polygala 12 parts, Jiaogulan 6 parts, Polygonum cuspidatum 20 parts, Puhuang 12 parts.

[0052] The preparation method of the pharmaceutical composition for treating atherosclerosis comprises the following steps:

[0053] (1) Extraction of traditional Chinese medicine components: add water to the raw materials of traditional Chinese medicines except kudzu root, Polygonum cuspidatum, Salvia miltiorrhiza and Puhuang, until they are submerged, decoct for 1 hour to obtain a decoct...

Embodiment 3

[0058] A pharmaceutical composition for treating atherosclerosis, which is made of the following raw materials in parts by weight: 2 parts of fenofibrate, 0.3 parts of probucol, and 180 parts of a Chinese medicine composition; 18 parts of Salvia miltiorrhiza, 12 parts of curcuma, 15 parts of kudzu root, 15 parts of Sophora japonica, 10 parts of tangerine peel, 18 parts of Hedyotis diffusa, 18 parts of Hovenia dulcis, 12 parts of fairy spleen, 25 parts of Atractylodes macrocephala, 10 parts of Cnidium, 15 parts of Polygala, 8 parts of Gynostemma, 30 parts of Polygonum cuspidatum, and 15 parts of Puhuang.

[0059] The preparation method of the pharmaceutical composition for treating atherosclerosis comprises the following steps:

[0060] (1) Extraction of traditional Chinese medicine components: add water to the raw materials of traditional Chinese medicines except kudzu root, Polygonum cuspidatum, Salvia miltiorrhiza and Puhuang, decoct for 2 hours to obtain a decoction, filter...

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PUM

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Abstract

The invention discloses a medicinal composition for treating atherosclerosis and a preparation method of the medicinal composition. The medicinal composition is prepared from the following raw materials in parts by weight: 1 to 2 parts of fibrate medicines, 0.1 to 0.9 part of probucol and 50 to 200 parts of traditional Chinese medicinal composition, wherein the traditional Chinese medicinal composition comprises salvia miltiorrhiza, zedoary, kudzuvine root, sophora japonica, dried orange peel, hedyotis diffusa, hovenia dulcis thumb, herba epimedii, rhizome of large-headed atractylodes, cnidium monnieri, milkwort, gynostemma pentaphyllum, polygonum cuspidatum and cattail pollen. According to the medicinal composition disclosed by the invention, the fibrate medicines and the probucol are combined for treating the atherosclerosis and both have remarkable synergistic effect, but have greater toxic or side effects; based on reasons, traditional Chinese medicinal raw materials are added for radical treatment and assisting two kinds of western medicines; according to the traditional Chinese medicinal composition provided by the invention, from root causes of disease, the atherosclerosis is thoroughly and effectively treated.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating atherosclerosis and a preparation method thereof. Background technique [0002] Atherosclerosis is a common cardiovascular disease. With the improvement of living standards and changes in eating habits in our country, the incidence of atherosclerosis has gradually increased. The disease has also become one of the main causes of death in patients with cardiovascular diseases in my country. . In the late stage of atherosclerosis, due to the action of metal matrix proteases, vulnerable plaques are exposed, coagulation factors and platelets are activated, platelet aggregation, thrombosis, and acute coronary syndrome, stroke, and vascular innervation Partial ischemic infarction seriously affects the physical and mental health of human beings. [0003] The current methods for treating atherosclerosis include surgical treatment, we...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K36/9066A61P9/10A61P3/06A61K31/10A61K31/216A61K31/192
Inventor 钟霞
Owner 钟霞
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