Medicinal composition for treating atherosclerosis and preparation method of medicinal composition

Abstract

The invention discloses a medicinal composition for treating atherosclerosis and a preparation method of the medicinal composition. The medicinal composition is prepared from the following raw materials in parts by weight: 1 to 2 parts of fibrate medicines, 0.1 to 0.9 part of probucol and 50 to 200 parts of traditional Chinese medicinal composition, wherein the traditional Chinese medicinal composition comprises salvia miltiorrhiza, zedoary, kudzuvine root, sophora japonica, dried orange peel, hedyotis diffusa, hovenia dulcis thumb, herba epimedii, rhizome of large-headed atractylodes, cnidium monnieri, milkwort, gynostemma pentaphyllum, polygonum cuspidatum and cattail pollen. According to the medicinal composition disclosed by the invention, the fibrate medicines and the probucol are combined for treating the atherosclerosis and both have remarkable synergistic effect, but have greater toxic or side effects; based on reasons, traditional Chinese medicinal raw materials are added for radical treatment and assisting two kinds of western medicines; according to the traditional Chinese medicinal composition provided by the invention, from root causes of disease, the atherosclerosis is thoroughly and effectively treated.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating atherosclerosis and a preparation method thereof. Background technique [0002] Atherosclerosis is a common cardiovascular disease. With the improvement of living standards and changes in eating habits in our country, the incidence of atherosclerosis has gradually increased. The disease has also become one of the main causes of death in patients with cardiovascular diseases in my country. . In the late stage of atherosclerosis, due to the action of metal matrix proteases, vulnerable plaques are exposed, coagulation factors and platelets are activated, platelet aggregation, thrombosis, and acute coronary syndrome, stroke, and vascular innervation Partial ischemic infarction seriously affects the physical and mental health of human beings. [0003] The current methods for treating atherosclerosis include surgical treatment, we...

AI Technical Summary

Problems solved by technology

However, when the drug is used in combination, especially when the dose is large, the occurrence of abnormal liver function and myolysis will increase significantly, and the adverse reactions will be more significant.

Although Western medicines are effective in treating diseases, they have relatively large toxic and side effects, strong irritation and dependence, and atherosclerosis cannot be eradicated.

[0007] The efficacy of traditional Chinese medicine in treating atherosclerosis has been proved by a large number of clinical trials. Traditional Chinese medicine can play a good role in regulating blood lipids and regulating the body's immunity. However, at present, traditional Chinese medicine preparations generally have problems such as slow onset of effect.

[0008] At present, there is no combined application of fibrates and probucol in the treatment of atherosclerotic diseases, and the use of traditional Chinese medicine excipients as carriers produces synergistic therapeutic effects