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A kind of composite film medical soft plastic infusion bag and preparation method thereof

A technology of composite film and infusion bag, which is applied in the field of medical materials to achieve the effect of ensuring storage period, strong flexibility and good inertness

Inactive Publication Date: 2018-01-16
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the defects of the current PVC infusion bag, the present invention provides a composite film medical soft plastic infusion bag and its preparation method. Polyvinyl chloride, is an ideal medical flexible packaging material

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A composite film medical soft plastic infusion bag, the components and the mass parts of each component are as follows: 20 parts of silk fibroin, 10 parts of chitosan, 4 parts of sodium gluconate, 15 parts of carboxyethyl cellulose, polyhexyl 8 parts of lactone, 15 parts of polylactide, 10 parts of starch, 8 parts of polyamide fiber, 1.8 parts of antioxidant 712, 3.6 parts of nucleating agent silicon dioxide, 1.5 parts of stabilizer sorbitol.

[0023] The preparation method comprises the steps of:

[0024] 1) Mix polycaprolactone, silk fibroin, chitosan and carboxyethyl cellulose evenly in parts by mass, heat to 140°C and stir for 30 minutes to obtain the mixed film material A;

[0025] 2) Mix polylactide, starch and polyamide fibers evenly in parts by mass, heat to 105°C and stir for 50 minutes to obtain mixed film material B;

[0026] 3) Sodium gluconate, antioxidant, nucleating agent and stabilizer are mixed evenly, and then co-extruded with mixed film material A an...

Embodiment 2

[0028] A composite film medical soft plastic infusion bag, the components and the mass parts of each component are as follows: 10 parts of silk fibroin, 5 parts of chitosan, 2 parts of sodium gluconate, 10 parts of carboxyethyl cellulose, polyhexyl 5 parts of lactone, 10 parts of polylactide, 5 parts of starch, 3 parts of polyamide fiber, 0.4 part of antioxidant 712, 1.2 parts of nucleating agent boron nitride, 0.5 part of stabilizer epoxy soybean oil.

[0029] The preparation method comprises the steps of:

[0030] 1) Mix polycaprolactone, silk fibroin, chitosan and carboxyethyl cellulose evenly in parts by mass, heat to 140°C and stir for 30 minutes to obtain the mixed film material A;

[0031] 2) Mix polylactide, starch and polyamide fibers evenly in parts by mass, heat to 105°C and stir for 50 minutes to obtain mixed film material B;

[0032] 3) Sodium gluconate, antioxidant, nucleating agent and stabilizer are mixed evenly, and then co-extruded with mixed film material A...

Embodiment 3

[0034] A composite film medical soft plastic infusion bag, the components and the mass parts of each component are as follows: 18 parts of silk fibroin, 8 parts of chitosan, 3.5 parts of sodium gluconate, 14 parts of carboxyethyl cellulose, polyhexyl 8 parts of lactone, 14 parts of polylactide, 8 parts of starch, 7 parts of polyamide fiber, 1.5 parts of antioxidant 425, 2.6 parts of nucleating agent silica, 1.2 parts of stabilizer epoxy soybean oil.

[0035] The preparation method comprises the steps of:

[0036] 1) Mix polycaprolactone, silk fibroin, chitosan and carboxyethyl cellulose evenly in parts by mass, heat to 140°C and stir for 30 minutes to obtain the mixed film material A;

[0037] 2) Mix polylactide, starch and polyamide fibers evenly in parts by mass, heat to 105°C and stir for 50 minutes to obtain mixed film material B;

[0038] 3) Sodium gluconate, antioxidant, nucleating agent and stabilizer are mixed evenly, and then co-extruded with mixed film material A an...

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PUM

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Abstract

The invention discloses a composite membrane medical soft plastic infusion bag and a preparation method thereof. The composite membrane medical soft plastic infusion bag includes the following components, by mass, silk fibroin, chitosan, sodium gluconate, carboxyethyl cellulose, polycaprolactone, polylactide, starch, polyamide fiber, an anti-oxidizing agent, a nucleating agent and a stabilizing agent. The anti-oxidizing agent is an anti-oxidizing agent 712 or an anti-oxidizing agent 425. The nucleating agent is silicon dioxide or boron nitride. The stabilizing agent is sorbitol or epoxidized soybean oil. The components of the composite membrane medical soft plastic infusion bag are all toxic-free and harmless. The infusion bag is produced in a compounding and pressing manner. The infusion bag is good in compatibility with a medicine liquid, is free of leakage of the medicine liquid, is thermal-stable, is strong in flexibility, is high in mechanical strength, is not liable to break, is easy to transport and storage, and can be used as an excellent medical soft packaging material for replacing polyvinyl chloride.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a composite film medical soft plastic infusion bag and a preparation method thereof. Background technique [0002] At present, there are about one billion bottles of infusion in our country. Most of the containers are glass bottles, and a small part are plastic bottles. However, glass bottles and plastic bottles have common defects such as easy contamination during use, which brings potential problems to clinical medication. hidden dangers. In recent years, plastic bag infusion has developed rapidly because of its advantages of simple manufacture, small production area, light weight, pressure resistance, convenient transportation, rapid infusion and less pollution during infusion. At present, most of the packaging materials of domestic infusion bags are polyvinyl chloride (PVC) materials. Although the price of raw materials is low, PVC infusion bags have ma...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L89/00C08L5/08C08L1/28C08L67/04C08L3/02C08L77/00C08K13/02C08K5/098C08K5/13C08K3/36C08K5/053C08K3/38
CPCC08L1/286C08L67/04C08L89/00C08L2203/02C08L2203/16C08L2205/035C08L2205/16C08L5/08C08L3/02C08L77/00C08K13/02C08K5/098C08K5/13C08K3/36C08K5/053C08K2003/385
Inventor 黄强林明山王天毅张园
Owner QINGDAO MUNICIPAL HOSPITAL