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Traditional Chinese medicine preparation for treating gastroesophageal reflux disease and preparation method thereof

A technology for gastroesophageal reflux and traditional Chinese medicine preparations is applied in the field of traditional Chinese medicine preparations for the treatment of gastroesophageal reflux disease and the field of preparation thereof, which can solve problems such as throat discomfort, foreign body sensation, mushy feeling, etc. The effect of recurrence and simple preparation process

Inactive Publication Date: 2016-05-18
杨春雪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

4. Other symptoms mainly include some patients with pharyngeal discomfort, foreign body sensation, cotton ball feeling or blockage feeling, but no real dysphagia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041] When the dosage form of the Chinese medicine preparation is syrup, its preparation method may further comprise the steps:

[0042] In the first step, mix Dixian peach, kudzu flower, radish leaf, plantain flower, red scorpion, rice straw, cattle and sheep grass knot and camphor root according to the stated ratio, and use an alcohol concentration of 5 to 8 times the mass of the obtained mixture Dissolve in 85%-95% ethanol, heat and reflux for 2-4 hours, extract, filter to obtain the first filtrate; use the filter residue again with alcohol concentration 85%-95% of 3-5 times the mass of the obtained mixture Dissolve in ethanol, heat and reflux for 2 to 4 hours, extract, filter to obtain the second filtrate; combine the first and second filtrates, recover the ethanol under reduced pressure and concentrate until the concentration of the medicinal solution is 1.2 to 1.4 g crude drug / mL, Use a macroporous adsorption resin column with a volume of 5 L for elution, first elute wi...

Embodiment 1

[0052] Embodiment 1: the syrup prepared by the present invention

[0053] Take 320g of Dixiantao, 250g of kudzu flower, 360g of radish leaf, 150g of plantain flower, 160g of red scorpion, 350g of straw, 270g of cattle and sheep grass knot, 190g of camphor root, 320g of ginger, 280g of chestnut shell, 170g of asparagus, 250g of sandalwood oil , 170g of ling vanilla, 350g of banyan fig and 70g of mallow leaves.

[0054] Its preparation method comprises the following steps:

[0055] In the first step, mix Dixian peach, kudzu flower, radish leaf, plantain flower, red scorpion, rice straw, cattle and sheep grass knot and camphor root according to the stated ratio, and use an alcohol concentration of 95% relative to 7 times the mass of the obtained mixture Dissolve in ethanol, extract after heating and reflux for 4 hours, filter to obtain the first filtrate; dissolve the filter residue with ethanol with 4 times the alcohol concentration of the obtained mixture again, extract after ...

Embodiment 2

[0058] Embodiment 2: tablet prepared by the present invention

[0059] Take 350g of Dixiantao, 220g of kudzu flower, 380g of radish leaf, 120g of plantain flower, 180g of red scorpion, 320g of straw, 290g of cattle and chinensis knot, 160g of camphor root, 340g of ginger, 260g of chestnut shell, 190g of asparagus, 210g of sandalwood oil , Ling vanilla 180g, fig 320g and mallow leaves 100g.

[0060] Its preparation method comprises the following steps:

[0061] In the first step, mix Dixian peach, kudzu flower, radish leaf, plantain flower and red scorpion according to the stated ratio, add ethanol with an alcohol concentration of 85% that is 5 times that of the mixture, and heat and reflux for 3 times, each reflux extraction After 2 hours, the extracts were combined, and the impurities were removed by centrifugation in a tubular centrifuge. The extracted extracts were concentrated under reduced pressure at 65°C to a medicinal solution with a relative density of 1.06 at 60°C. ...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating a gastroesophageal reflux disease and a preparation method thereof. The traditional Chinese medicine preparation is prepared from raw material medicines including fruit of lithospermum zollingeri DC., lobed kudzuvine flowers, radish leaves, Japanese banana flowers, manchurian tubergourd fruit, rice straw, grass agglomerates in the stomach of oxen or goats, cinnamomum camphora roots, Chinese galangal rhizomes, poppy shells, herba eleocharitis, sandalwood oil, lysimachia foenum-graecum, root bark of ficus esquiroliana and malva verticillata leaves. The traditional Chinese medicine preparation and the preparation method thereof have the advantages that the gastroesophageal reflux disease is treated by combining the traditional Chinese medicine preparation with Western medicine, use is convenient, the treatment effect of the Western medicine is effectively improved, the cure rate of the Western medicine is effectively improved, no toxic or side effect or adverse effect is generated, relapse is not prone to occurrence, and the preparation technology is simple.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine preparation for treating gastroesophageal reflux disease and a preparation method thereof. Background technique [0002] Gastroesophageal reflux disease (GERD) refers to the reflux of excessive gastric and duodenal contents into the esophagus, causing symptoms such as heartburn, and can lead to esophagitis and tissue damage outside the esophagus such as pharynx, larynx, and airway. Gastroesophageal reflux disease is very common in western countries. About 7%-15% of the population has gastroesophageal reflux symptoms. The incidence increases with age. The peak age of onset is 40-60 years old. For patients with esophagitis, there are more men than women (2:1 to 3:1). Compared with Western countries, the incidence of gastroesophageal reflux disease in my country is relatively low, and the condition is also relatively m...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P1/04A61K35/38
CPCA61K36/9062A61K9/0095A61K9/2059A61K9/28A61K35/38A61K36/185A61K36/30A61K36/31A61K36/42A61K36/48A61K36/54A61K36/60A61K36/88A61K36/89A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 杨春雪杨希文
Owner 杨春雪
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