A kind of dimethylorphane phosphate capsule composition and preparation method thereof
A technology of dimethylphene phosphate and a composition, which is applied in the field of dimethylphene phosphate capsule composition and preparation thereof, and achieves the effects of huge social benefit, reasonable selection and ratio of auxiliary materials, and realization of economic benefits.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0044] Product formula: calculated on the basis of making 1000 products, the ingredients include the following components in parts by weight (or mass):
[0045]
[0046] Preparation:
[0047] 1) Pass 10.0 g of dimethylorphinyl phosphate through a 100-mesh sieve and set aside.
[0048] 2) Weigh the prescribed amount of povidone K30, and prepare a 3% povidone K30 solution with 50% ethanol for future use.
[0049]3) Weigh the prescribed amount of dimethylorphinyl phosphate, lactose, microcrystalline cellulose and low-substituted-hydroxypropyl cellulose, mix them evenly, and mix them for 10 minutes. Use the 3% povidone K30 solution obtained in step (2) to make soft materials, granulate with a 30-mesh sieve, and dry the wet granules at 50°C to 60°C for 2 hours until the water content is less than 2%, and the dry granules pass through 30 mesh Sieve the granules, add the prescribed amount of silicon dioxide and magnesium stearate, and mix well.
[0050] 4) filling capsules.
...
Embodiment 2
[0053] Product formula: calculated on the basis of making 1000 products, the ingredients include the following components in parts by weight (or mass):
[0054]
[0055] Preparation:
[0056] 1) Pass 10 g of dimethylorphinyl phosphate through a 100-mesh sieve, and set aside.
[0057] 2) Weigh the prescribed amount of povidone K30, and prepare a 3% povidone K30 solution with 50% ethanol for future use.
[0058] 3) Weigh the prescribed amount of dimethylorphinyl phosphate, lactose, microcrystalline cellulose and sodium carboxymethyl starch, mix well, and mix for 10 minutes. Use the 3% povidone K30 solution obtained in step (2) to make soft materials, granulate with a 30-mesh sieve, and dry the wet granules at 50°C to 60°C for 2 hours until the water content is less than 2%, and the dry granules pass through 30 mesh Sieve the granules, add the prescribed amount of silicon dioxide and magnesium stearate, and mix well.
[0059] 4) filling capsules.
[0060] The angle of repo...
Embodiment 3
[0062] Product formula: calculated on the basis of making 1000 products, the ingredients include the following components in parts by weight (or mass):
[0063]
[0064]
[0065] Preparation:
[0066] 1) Pass 10 g of dimethylorphinyl phosphate through a 100-mesh sieve, and set aside.
[0067] 2) Weigh the prescribed amount of povidone K30, and prepare a 3% povidone K30 solution with 50% ethanol for future use.
[0068] 3) Weigh the prescribed amount of dimethylorphinyl phosphate, lactose, microcrystalline cellulose and crospovidone XL, mix them evenly, and mix them for 10 minutes. Use the 3% povidone K30 solution obtained in step (2) to make soft materials, granulate with a 30-mesh sieve, and dry the wet granules at 50°C to 60°C for 2 hours until the water content is less than 2%, and the dry granules pass through 30 mesh Sieve the granules, add the prescribed amount of silicon dioxide and magnesium stearate, and mix well.
[0069] 4) filling capsules.
[0070] The a...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More