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Manufacturing process and application of PVA sponge functional dressing

A technology of sponge function and production process, which is applied in the field of medical sponges, can solve the problems of high price, complicated production process, and high production cost of hemostatic sponges, achieve excellent hemostatic effect, simple production process, and reduce production costs

Inactive Publication Date: 2016-09-07
JIANGSU KANGBO MEDICAL DEVICES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In addition, most of the current hemostatic sponges are made by dissolving and mixing the sponge material and the hemostatic material, and then cross-linking and freeze-drying. Dissolving and cross-linking to re-form the sponge, the production process is relatively complicated, and it needs to be dried by freeze-drying process, the production cost is high, resulting in a high price of the hemostatic sponge
Also have, because the liquid absorption effect of existing hemostatic sponge is relatively poor, adopt surgical cotton piece to carry out hemostasis after liquid absorption usually in operation, inconvenient operation, although the liquid absorption effect of surgical cotton sheet is better, but hemostasis The effect is poor, so there is an urgent need to develop a functional dressing for surgery that has both good hemostatic effect and good fluid absorption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A kind of PVA sponge functional dressing manufacturing process of the present embodiment comprises the following steps:

[0037] (a) Take 7g of hydroxyethyl cellulose and disperse it evenly with 14g of glycerin, add 100g of purified water, stir at a speed of 525r / min, and after stirring for 1h, place the solution in a water bath at 20°C for 2h;

[0038] (b) Soak the PVA sponge with polyethylene glycol solution for 1 hour, then centrifuge and dry it, wash it with purified water for 2 times, and then dry it;

[0039] (c) Put the clean PVA sponge in a stirring container, add the mixed solution in step (a), stir for 0.5 hours, let it stand for 3 hours, take it out, put it in a 40°C oven until dry, and pack it in a sterile package.

[0040] The functional dressing made by the above process can expand by 1.5 times in diameter after being immersed in liquid, and the liquid absorption rate is more than 5 times of its own weight. Compared with traditional water-absorbing materia...

Embodiment 2

[0042] A kind of PVA sponge functional dressing manufacturing process of the present embodiment comprises the following steps:

[0043] (a) Take 15g of chitosan and disperse evenly with 12g of ethanol, add 100g of purified water, stir at a speed of 640r / min, after stirring for 2h, place the solution in a water bath at 40°C for 5h;

[0044] (b) Soak the PVA sponge with polyethylene glycol solution for 3 hours, then centrifuge and dry it, wash it once with purified water, and then dry it;

[0045] (c) Put the clean PVA sponge in a stirring container, add the mixed solution in step (a), stir for 2 hours, let it stand for 0.5 hours, take it out, put it in a 60°C oven until dry, and pack it in a sterile package.

[0046] The functional dressing made by the above process can expand by 1.3 times in diameter after being soaked in liquid, and the liquid absorption rate is more than 5 times of its own weight. Compared with traditional water-absorbing materials, the wound healing time can ...

Embodiment 3

[0048] A kind of PVA sponge functional dressing manufacturing process of the present embodiment comprises the following steps:

[0049] (a) Take 10g of carboxymethylcellulose and 5g of hydroxypropylmethylcellulose and disperse them evenly with 10g of ethanol and 10g of glycerin, then add 100g of purified water, stir at a speed of 500r / min, and after stirring for 2 hours, put the solution in Water bath in 40℃ water bath for 3h;

[0050] (b) Soak the PVA sponge with polyethylene glycol solution for 2 hours, then centrifuge and dry it, wash it with purified water for 3 times, and then dry it;

[0051] (c) Put the PVA sponge in a stirring container, add the mixed solution in step (a), stir for 2 hours, let it stand for 0.5 hours, take it out, put it in a 30°C oven until dry, and pack it in a sterile package.

[0052] The functional dressing made by the above process can expand by 1.4 times in diameter after being immersed in liquid, and the liquid absorption rate is more than 4 t...

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PUM

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Abstract

The invention discloses a manufacturing process and application of PVA (Polyvinyl Alcohol) sponge functional dressing, and belongs to the field of medical apparatuses and instruments. The manufacturing process disclosed by the invention comprises the following steps: (a) stirring and uniformly dispersing a certain quantity of polymer cellulose materials in a dispersant to form a mixed solution, and maintaining a temperature; (b) placing clean PVA sponge in the mixed solution of the step (a), and then stirring and standing; (c) taking out the PVA sponge which is soaked in the solution in the step (b), drying or spin-drying, and then sterilizing and packaging. The manufacturing process disclosed by the invention is simple in process and low in manufacturing cost; the manufactured function dressing has an excellent bleeding stopping effect, and also has the advantages that fluid is absorbed quickly at a high speed, the surface is smooth, soft and comfortable, fibres do not fall off easily, the tear strength and breaking elongation are excellent, the rebound resilience is good and the like, and can be widely applied to the medical fields, such as preoperative wound cleaning, intraoperative fluid absorption and bleeding stopping, postoperative care and the like.

Description

technical field [0001] The present invention relates to a kind of medical sponge, more specifically, relates to a kind of PVA sponge functional dressing production process and application. Background technique [0002] Skin is the outermost protective tissue of the human body and the main barrier for the human body to contact the external environment. Human skin is extremely vulnerable to physical, mechanical and chemical damage in the environment. According to statistics, among people aged 5-44 years old worldwide, the number of deaths due to trauma accounts for 10% of the total death toll, which is the main cause of death in this age group. Uncontrolled hemorrhage during trauma is an important cause of death, accounting for 30% to 40% of trauma-related deaths. Therefore, early control of uncontrolled hemorrhage has always been a research hotspot in the medical field. In addition, rapid, simple and effective hemostasis is also of great significance in certain surgical tre...

Claims

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Application Information

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IPC IPC(8): A61L15/24A61L15/28A61L15/42
CPCA61L15/24A61L15/28A61L15/425A61L2400/04C08L29/04C08L1/08
Inventor 汪世琼周君兰
Owner JIANGSU KANGBO MEDICAL DEVICES CO LTD
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