A degradable composite surgical suture
A technique for surgery and sutures, applied in the field of degradable composite surgical sutures, can solve problems such as unreported, and achieve the effects of good mechanical properties, simplified handling, good biological activity and biocompatibility
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Embodiment 1
[0035] (1) Preliminary purification of CT. CT was used in hydrochloric acid (1mol / L) and sodium hydroxide (0.2mol / L) to remove inorganic salts and proteins, each for 1h. Wash in distilled water until neutral and dry. In addition, the GO aqueous solution was prepared by the Hummers method.
[0036] (2) CT and GO purified in step 1 are dissolved in dispersion liquid, wherein the composition of dispersion liquid is the aqueous solution of sodium hydroxide and urea, and the mass percentage of sodium hydroxide (NaOH) is 11wt% in this aqueous solution, urea ( The mass percent of Urea) is 4%.
[0037] In the mixed solution, the total amount of CT and GO added accounted for 6% of the aqueous solution mass (saturated state), wherein GO accounted for 6% of the total amount of CT and GO added (in terms of mass percentage). Then freeze-thaw at ultra-low temperature (-80°C) overnight. After melting at room temperature and stirring evenly, filter with 200-mesh silk cloth. Then mix the ...
Embodiment 2
[0043] Embodiment 2: The method is the same as in Example 1, except that GO accounts for 8% of the total amount added of CT and GO in step (2), and all the other steps are the same.
Embodiment 3
[0044] Embodiment 3: The method is the same as in Example 1, except that GO accounts for 10% of the total amount added of CT and GO in step (2), and all the other steps are the same.
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