Ultrasonic echo statistical parameter imaging system and method for thermal coagulation monitoring

An ultrasonic echo and imaging system technology, applied in the direction of ultrasonic/sonic/infrasonic Permian technology, ultrasonic/sonic/infrasonic image/data processing, ultrasonic/sonic/infrasonic diagnosis, etc., can solve the problem of coagulation initiation and coagulation Difficulties in bottom detection and monitoring imaging, etc., to achieve the effect of optimizing detection and monitoring imaging effects, enhancing the display of the lower part of solidification, and improving functions

Inactive Publication Date: 2016-10-26
XI AN JIAOTONG UNIV
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Problems solved by technology

[0003] Due to the influence of cavitation, vaporization microbubbles and strong echo regions during the ablation process, it is difficult to detect and monitor the coagulation initiation and coagulation bottom during thermal ablation

Method used

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  • Ultrasonic echo statistical parameter imaging system and method for thermal coagulation monitoring
  • Ultrasonic echo statistical parameter imaging system and method for thermal coagulation monitoring
  • Ultrasonic echo statistical parameter imaging system and method for thermal coagulation monitoring

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Effect test

Embodiment 1

[0072] see Figure 4 , Coagulation initiation detection and ultrasound monitoring imaging during thermal ablation. In the early stage of thermal ablation therapy, the ultrasound echo statistical parametric imaging method was used to detect and monitor the onset of thermal coagulation.

[0073] In this embodiment, focused ultrasound is used for thermal ablation therapy. The sound power used is 85W, the duty cycle is 70%, and the total time is 4s. During the thermal ablation process, the image acquisition equipment is used to collect the dynamic change process of the damage in the transparent biological tissue phantom during the thermal ablation treatment with focused ultrasound. If shown in 4(a). At the same time, in the process of thermal ablation, the ultrasonic echo backscatter data of the target area in the process of thermal ablation treatment is collected synchronously with the all-digital ultrasound equipment. Use these collected ultrasound echo RF data to simultaneou...

Embodiment 2

[0075] see Figure 5 , the dynamic changes and monitoring imaging of the statistical parameters of the lower part of the ultrasonic echo during thermal coagulation when the upper part of the hyperechoic area blocks the heat during the thermal ablation process. During the thermal ablation process, the ultrasonic echo amplitude and ultrasonic echo statistical parameters of multiple regions of the sample are detected synchronously. At the same time, the ultrasonic echo statistical parameter image and the ultrasonic B-mode image are constructed simultaneously.

[0076] In this embodiment, a microwave therapeutic apparatus is used for thermal ablation therapy. The parameters of microwave thermal ablation are: the ablation power is 40W, and the ablation time is 5min. During the thermal ablation process, the ultrasonic detection and imaging transducers are controlled by fully digital ultrasonic equipment to collect the ultrasonic echo radio frequency data of the thermal ablation tar...

Embodiment 3

[0078] see Figure 6 , Monitoring imaging of thermal coagulation based on ultrasonic echo-statistical parameters increasing the ratio of thermally coagulated microbubbles. During the thermal ablation process, the ultrasonic echo data and ultrasonic echo statistical parameter data of the coagulation area and the microbubble area are respectively extracted, the average amplitude of the ROI area is calculated, and the LBR value and its dynamic changes are calculated according to the formula. Echo statistical parametric images and B-mode ultrasound images.

[0079] In this embodiment, focused ultrasound is used for thermal ablation treatment, the sound power is 140W, and continuous radiation is 32s. During the thermal ablation treatment, a fully digital ultrasound device is used to synchronously collect ultrasonic echo radio frequency data of the target area during the thermal ablation process. Use these RF data to simultaneously construct B-mode images during thermal ablation ...

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Abstract

The invention discloses an ultrasonic echo statistical parameter imaging system and method for thermal coagulation monitoring. The imaging system comprises main control equipment, a power amplifier, a noninvasive power transducer, an ultrasonic detection and imaging transducer, full-digital ultrasonic equipment, data collection equipment, a sample, image collection equipment, an indicator lamp, a minimally invasive power transducer, a light-transmitting water tank and three-dimensional mobile equipment. According to the invention, the ultrasonic echo statistical parameter imaging method, which overcomes micro-bubble coverage and upper strong echo region sheltering, is adopted to monitor a process of forming thermal coagulation, so that early detection of the initiation of the thermal coagulation is achieved, lower part display of the thermal coagulation is enhanced and a thermal coagulation micro-bubble ratio in a thermal ablation process is improved so as to enhance a contrast ratio of the thermal coagulation monitoring.

Description

【Technical field】 [0001] The invention belongs to ultrasonic detection and monitoring imaging technology, relates to the fields of biomedicine and information, in particular to an ultrasonic echo statistical parameter imaging system and method for thermocoagulation monitoring. 【Background technique】 [0002] The thermal ablation technology based on the mechanism of irreversible thermal coagulation of protein caused by temperature rise has the advantages of non-invasive or minimally invasive, fast, and small side effects. Thermal ablation achieved by "green" physical energy such as radio frequency, microwave, ultrasound, and laser at home and abroad The technology has achieved encouraging results in the fields of biology, medicine, chemistry and industry, especially in the domestic use of high-intensity focused ultrasound thermal ablation technology to treat tumors. The detection and monitoring imaging of the thermal coagulation process is the basis and guarantee for efficien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B8/08A61B8/00
CPCA61B8/08A61B8/0833A61B8/5246
Inventor 张思远朱兴广韩玉强黄国静尚少强徐田奇万明习段君博钟徽
Owner XI AN JIAOTONG UNIV
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