Molecularly imprinted magnetic microspheres for triazole pesticides and application of molecularly imprinted magnetic microspheres

Abstract

The invention relates to the field of pesticide residue extraction and detection methods, in particular to molecularly imprinted magnetic microspheres for triazole pesticides and an application of themolecularly imprinted magnetic microspheres. The magnetic microspheres are prepared with a method comprising steps as follows: 1), Fe3O4 magnetic nanoparticles are prepared with a coprecipitation method, surfaces of the Fe3O4 magnetic nanoparticles are modified with propenyl, and propenyl treatedFe3O4 magnetic shells are obtained; 2), molecularly imprinted polymers capable of recognizing triazolepesticide molecules are synthesized on the surfaces of the propenyl treated Fe3O4 magnetic shells, and the molecularly imprinted magnetic microspheres are obtained. With adoption of a surface imprinting technique, the self-made functional magnetic nanoparticles are taken as carriers for preparation of the magnetic molecularly imprinted nano polymers, an MI-MDSPE-LC-MS / MS method for the triazole pesticides is established on the basis of a magnetic separation technology, synchronous detection of 20 triazole pesticides in a cucumber substrate is realized, so that solid-phase extraction time andcost are saved, and pretreatment speed is effectively increased.

Description

technical field [0001] The invention relates to the field of pesticide residue extraction and detection methods, in particular to a molecularly imprinted magnetic microsphere of triazole pesticides and an application thereof. Background technique [0002] Molecularly imprinted polymers (MIPs) are artificially designed and prepared specific molecular recognition materials. The preparation methods mainly include precipitation polymerization, bulk polymerization, surface polymerization and other methods. At present, molecularly imprinted polymers have been used as solid Phase extraction sorbents are used for complex sample pretreatment, effectively realizing the analysis and detection of trace substances in complex sample matrices. Triazole pesticides have shown great potential in controlling pests and diseases since their appearance in the 1970s. Triazole pesticides are mainly fungicides, which generally have the characteristics of high efficiency, low toxicity, low residue, ...

AI Technical Summary

Problems solved by technology

[0004] At present, the preparation methods of molecularly imprinted polymers of triazole compounds adopt traditional bulk polymerization and precipitation polymerization methods, which have disadvantages such as poor adsorption uniformity, weak class-specific recognition ability, and low adsorption flux. centrifugation and other cumbersome processes

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