A gold nanosheet synthesizing method and applications of a gold nanosheet in breast cancer diagnosis and treatment

A synthesis method and gold nanotechnology, applied in the field of gold nanosheets, can solve the problems of no precious metal nanoparticle silica sheets, low catalytic reaction efficiency of catalysts, weakened SERS signal, etc., and achieve obvious signal amplification function, saving resources, surface smooth effect

Active Publication Date: 2016-11-09
SOUTHEAST UNIV
View PDF7 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the core-shell structure also exposes a very serious problem, that is, the characteristics of the catalyst are reduced or hidden due to the packaging of inorganic materials, such as the low catalytic reaction efficiency of the catalyst and the weakenin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A gold nanosheet synthesizing method and applications of a gold nanosheet in breast cancer diagnosis and treatment
  • A gold nanosheet synthesizing method and applications of a gold nanosheet in breast cancer diagnosis and treatment
  • A gold nanosheet synthesizing method and applications of a gold nanosheet in breast cancer diagnosis and treatment

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0037] The present invention will be further clarified below in conjunction with the drawings and specific embodiments.

[0038] The chemical reaction raw materials are as follows,

[0039] Tetraethylorthosilicate (TEOS); Sodium hydroxide; Absolute ethanol; Ethyl acetate; Triaminopropyltriethoxysilane (APTS); Chloroauric acid (1%); Ascorbic acid (AA); Hydrofluoride Acid; deionized water is double distilled water. The above reagents are of analytical grade.

[0040] The synthesis of gold nanosheet composites is divided into five steps. First, the silica nanosheets are synthesized; then, the surface modification of the silica nanosheets; and then the chloroauric acid ions are adsorbed on the surface of the silica sheet. And through the slow reduction, the growth of gold nanosheets on the surface of the silicon dioxide sheet is promoted; the silicon dioxide sheet template is finally etched away, so that monodisperse gold nanosheets can be obtained; the specific operation steps are as ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a gold nanosheet synthesizing method and belongs to the technical field of gold nanosheets. The method includes 1) synthesizing a monodispersed silica nanosheet, 2) subjecting the monodispersed silica nanosheet to surface modification, 3) subjecting the silica nanosheet to chloroauric acid ion surface adsorption, 4) synthesizing a gold nanosheet/silica sheet composite material and 5) etching a hard template silica sheet to produce a monodispersed gold nanosheet. The method provides a novel idea for synthesizing precious metal nanometer materials. According to applications of the gold nanosheet synthesized by the method in breast cancer diagnosis and treatment, signal amplification is performed through SERS enhancement to monitor cancer cells, and unique near infrared absorption functions allow the gold nanosheet to integrate monitoring and treatment in a breast cancer treating process, thus improving application value of the gold nanosheet.

Description

technical field [0001] The invention belongs to the technical field of gold nanosheets, and in particular relates to a synthesis method of gold nanosheets and an application of gold nanosheets in diagnosis and treatment of breast cancer. Background technique [0002] In recent years, noble metal nanomaterials have attracted more and more attention due to their excellent performance in catalysis, electronics, and chemical sensing. At the same time, many shortcomings of noble metal nanoparticles are gradually exposed, such as high surface energy, easy agglomeration during the reaction process, limited resources and no regeneration. [0003] In order to optimize the properties of precious metals to reduce production costs and improve resource utilization, researchers have proposed two solutions. The first is to synthesize a variety of nanoparticles by means of controlled growth to increase the properties of precious metals. , such as palladium nanosheets and gold nanocages hav...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K49/00A61K41/00A61K47/04A61P35/00A61P15/14B22F9/24B22F1/00C01B33/12B82Y30/00B82Y40/00
CPCA61K41/0052A61K47/02A61K49/00B82Y30/00B82Y40/00C01B33/12B22F9/24C01P2004/03C01P2004/04C01P2004/64B22F1/0551B22F1/068B22F1/054
Inventor 王志飞汤雪娇王肖肖杨丹丹
Owner SOUTHEAST UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap