A gold nanosheet synthesizing method and applications of a gold nanosheet in breast cancer diagnosis and treatment

Abstract

The invention discloses a gold nanosheet synthesizing method and belongs to the technical field of gold nanosheets. The method includes 1) synthesizing a monodispersed silica nanosheet, 2) subjecting the monodispersed silica nanosheet to surface modification, 3) subjecting the silica nanosheet to chloroauric acid ion surface adsorption, 4) synthesizing a gold nanosheet / silica sheet composite material and 5) etching a hard template silica sheet to produce a monodispersed gold nanosheet. The method provides a novel idea for synthesizing precious metal nanometer materials. According to applications of the gold nanosheet synthesized by the method in breast cancer diagnosis and treatment, signal amplification is performed through SERS enhancement to monitor cancer cells, and unique near infrared absorption functions allow the gold nanosheet to integrate monitoring and treatment in a breast cancer treating process, thus improving application value of the gold nanosheet.

Description

technical field [0001] The invention belongs to the technical field of gold nanosheets, and in particular relates to a synthesis method of gold nanosheets and an application of gold nanosheets in diagnosis and treatment of breast cancer. Background technique [0002] In recent years, noble metal nanomaterials have attracted more and more attention due to their excellent performance in catalysis, electronics, and chemical sensing. At the same time, many shortcomings of noble metal nanoparticles are gradually exposed, such as high surface energy, easy agglomeration during the reaction process, limited resources and no regeneration. [0003] In order to optimize the properties of precious metals to reduce production costs and improve resource utilization, researchers have proposed two solutions. The first is to synthesize a variety of nanoparticles by means of controlled growth to increase the properties of precious metals. , such as palladium nanosheets and gold nanocages hav...

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Problems solved by technology

However, the core-shell structure also exposes a very serious problem, that is, the characteristics of the catalyst are reduced or hidden due to the packaging of inorganic materials, such as the low catalytic reaction efficiency of the catalyst and the weakening of the SERS signal.

[0004] In recent years, although noble metal nanoparticles have been supported on various inorganic materials, there have been no reports of noble metal nanoparticles supported on silica sheets, especially the synthesis of silica nanosheets.

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