Compound traditional Chinese medicine preparation capable of regulating blood lipid

Abstract

The invention discloses a compound traditional Chinese medicine preparation capable of regulating blood lipid. According to the invention, warm-natured red yeast rice capable of drying dampness, eliminating phlegm and activating blood circulation to dissipate blood stasis is compounded with cool-natured fiveleaf gynostemma herb capable of benefiting qi, activation blood circulation, eliminating phlegm and transforming stasis, and synergism of the activities of both of the above-mentioned medicines is realized, so the compound traditional Chinese medicine preparation has improved harmonizing, qi-rectifying, phlegm-reducing and stasis-removing effects; and thus, the blood-lipid-reducing effect of the compound traditional Chinese medicine preparation is reinforced. To further improve the efficacy of the compound traditional Chinese medicine preparation, fermented red yeast rice with a medicinal function and gypenosides can be used together with a pharmaceutically acceptable accessory material for preparation of an oral preparation. Results of animal experiments show that the compound preparation has good synergism and presents more substantial treatment effect compared with separate usage of a Zhibituo tablet containing a same dosage of red yeast rice or a gypenoside tablet containing a same dosage of gypenosides. Moreover, the compound traditional Chinese medicine preparation has no toxic and side effect, good tolerance, low price and suitability for long-term treatment and usage.

Description

technical field [0001] The invention belongs to the field of medicine, in particular to a compound preparation with medicinal functional red yeast rice and medicinal gypenosides as active ingredients, which is mainly used for the mediation of blood lipids and the treatment of non-alcoholic fatty liver. Background technique [0002] Hyperlipidemia, also known as hyperlipidemia, manifested as dyslipidemia, is a common metabolic syndrome characterized by lipid disorders, and its characteristics include hypercholesterolemia, hypertriglyceridemia and familial mixed hyperlipidemia Lipidemia, which can lead to some other metabolic diseases, such as atherosclerosis, nonalcoholic fatty liver disease, cardiovascular disease, diabetes, insulin resistance and obesity. Atherosclerosis caused by dyslipidemia can lead to coronary artery disease and stroke, which is one of the main causes of death in middle-aged and elderly people. In the past ten years, with the changes in Chinese lifesty...

AI Technical Summary

Problems solved by technology

Fibrate is a kind of ligand of peroxisome proliferator-activated receptor α (PPAR-α), which is the first choice drug for lowering TG, and also has a strong effect of raising HDL-C; statins are also called HMG-CoA reductase inhibitors can effectively inhibit the activity of HMG-CoA reductase, the key enzyme in cholesterol biosynthesis, thereby reducing TC and LDL-C, and play a role in regulating abnormal blood lipids in the human body. According to data, statins are large Temporary reactions such as myalgia, gastrointestinal tract reactions, and headaches may occur in some patients during dosage application; while bile acid-binding resin drugs are used in large dosages, and have special odor and certain irritation. After medication, there may be nausea, Constipation, abdominal distension, loss of appetite and other adverse reactions usually disappear after two weeks; the application of fibrates and niacin can cause gastrointestinal discomfort and liver and kidney damage

Images