Micro-capsule coating sodium butyrate and preparation method thereof
A technology of coating sodium butyrate and sodium butyrate, which is applied in the direction of adding food elements, forming or processing animal feed, animal feed, etc., can solve the problem of inability to meet the nutritional needs of butyric acid, difficulty reaching the colon, and affecting Feed quality approval and other issues, to achieve the effect of animal body transformation, inhibit intestinal inflammation, and promote intestinal mucosal repair
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[0019] The preparation method of microcapsule coated sodium butyrate provided by the invention comprises:
[0020] Step 1. Accurately weigh each raw material in proportion. The raw material includes sodium butyrate, antibacterial peptide, supplementary powder, glucose, polyethylene glycol and drinking water, and the weight ratio is 120:36:54:50:4:5.
[0021] Supplementary powder is a water-soluble solid dispersion carrier, the main components are inorganic salts, soluble starch and other excipients, used as a new generation of veterinary drug soluble excipients, the source is commercially available.
[0022] Antimicrobial peptides, also known as antimicrobial peptides, are a kind of polypeptide substances with a molecular weight of about 4KD and antibacterial activity induced by insects. They are part of the body's natural immune defense system and can also be used as feed for livestock and poultry. The additive replaces or partially replaces the antibiotics currently used to ...
Embodiment 1
[0034] Microcapsule-coated sodium butyrate was prepared according to the following steps.
[0035] Step 1. Accurately weigh each raw material in proportion. The raw material includes sodium butyrate, antibacterial peptide, supplementary powder, glucose, polyethylene glycol and drinking water, and the weight ratio is 120:36:54:50:4:5.
[0036] Specifically, sodium butyrate 60kg (purchased 20kg / bag content 97%); antibacterial peptide 18kg; supplementary powder 27kg; polyethylene glycol 25kg; glucose 2kg; drinking water 2.5kg.
[0037] Step 2, add sodium butyrate, supplement powder, glucose and drinking water into the tank mixer, and mix for 5 minutes.
[0038] In step 3, polyethylene glycol is heated to 130° C. and then added to the mixed material obtained in step 2, and the mixing is continued for 10 minutes.
[0039] In step 4, the mixture obtained in step 3 is naturally cooled to room temperature, then the antimicrobial peptide is added, and the mixture is continued for 10 m...
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