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Micro-capsule coating sodium butyrate and preparation method thereof

A technology of coating sodium butyrate and sodium butyrate, which is applied in the direction of adding food elements, forming or processing animal feed, animal feed, etc., can solve the problem of inability to meet the nutritional needs of butyric acid, difficulty reaching the colon, and affecting Feed quality approval and other issues, to achieve the effect of animal body transformation, inhibit intestinal inflammation, and promote intestinal mucosal repair

Inactive Publication Date: 2017-04-19
赵清国
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, sodium butyrate also has great defects in its application: for example, it has a strange smell, which affects the recognition of feed quality; it is highly irritating to the esophagus and stomach; it is easy to absorb moisture, which affects the processing quality of feed; it cannot satisfy the intestinal Most of the nutritional requirements for butyric acid in each segment of the intestinal tract are absorbed by the small intestine, and it is difficult to reach the colon; the active ingredient cannot pass the stomach, and it is difficult to enter the intestinal tract, etc.

Method used

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  • Micro-capsule coating sodium butyrate and preparation method thereof
  • Micro-capsule coating sodium butyrate and preparation method thereof

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preparation example Construction

[0019] The preparation method of microcapsule coated sodium butyrate provided by the invention comprises:

[0020] Step 1. Accurately weigh each raw material in proportion. The raw material includes sodium butyrate, antibacterial peptide, supplementary powder, glucose, polyethylene glycol and drinking water, and the weight ratio is 120:36:54:50:4:5.

[0021] Supplementary powder is a water-soluble solid dispersion carrier, the main components are inorganic salts, soluble starch and other excipients, used as a new generation of veterinary drug soluble excipients, the source is commercially available.

[0022] Antimicrobial peptides, also known as antimicrobial peptides, are a kind of polypeptide substances with a molecular weight of about 4KD and antibacterial activity induced by insects. They are part of the body's natural immune defense system and can also be used as feed for livestock and poultry. The additive replaces or partially replaces the antibiotics currently used to ...

Embodiment 1

[0034] Microcapsule-coated sodium butyrate was prepared according to the following steps.

[0035] Step 1. Accurately weigh each raw material in proportion. The raw material includes sodium butyrate, antibacterial peptide, supplementary powder, glucose, polyethylene glycol and drinking water, and the weight ratio is 120:36:54:50:4:5.

[0036] Specifically, sodium butyrate 60kg (purchased 20kg / bag content 97%); antibacterial peptide 18kg; supplementary powder 27kg; polyethylene glycol 25kg; glucose 2kg; drinking water 2.5kg.

[0037] Step 2, add sodium butyrate, supplement powder, glucose and drinking water into the tank mixer, and mix for 5 minutes.

[0038] In step 3, polyethylene glycol is heated to 130° C. and then added to the mixed material obtained in step 2, and the mixing is continued for 10 minutes.

[0039] In step 4, the mixture obtained in step 3 is naturally cooled to room temperature, then the antimicrobial peptide is added, and the mixture is continued for 10 m...

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Abstract

The invention discloses micro-capsule coating sodium butyrate and a preparation method thereof. The method comprises the steps of (1) accurately weighing raw materials in proportion, wherein the raw materials comprise sodium butyrate, antimicrobial peptide, tonifying powder, glucose, polyethylene glycol and drinking water; (2) mixing the sodium butyrate, the tonifying powder, the glucose and the drinking water; (3) heating the polyethylene glycol, and adding the heat polyethylene glycol into an obtained mixed material for continuously mixing; (4) naturally cooling an obtained mixed material, and then adding antimicrobial peptide for continuously mixing; (5) granulating a mixed material; (6) drying the granulated material; (7) sampling and inspecting; (8) packaging qualified products, and indicating batches; and (9) inspecting and putting in storage. The invention further discloses the micro-capsule coating sodium butyrate prepared by the invention. According to the micro-capsule coating sodium butyrate and the preparation method thereof provided by the invention, the intestine development of beasts and birds can be promoted, the growth and the propagation of harmful bacteria can be inhibited, the occurrence of intestinal diseases is prevented, and the economic benefit is increased.

Description

technical field [0001] The invention relates to a biological additive, in particular to a microcapsule-coated sodium butyrate and a preparation method thereof. Background technique [0002] The development of the breeding industry is becoming more and more modern, resources are becoming more and more tense, and animal protection is becoming more and more stringent (animal welfare has been advocated abroad, but there is still a blank in our country). How to maximize the benefits with the least input is the key to all intensification. Breeding is the most important thing to care about, but the current limited breeding methods, the density of the breeding population is high, the range of activities is small, the physique cannot be exercised, and the food is full-price feed with a high conversion rate, resulting in the loss of livestock and poultry bodies. The function is constantly weakened, the physique becomes poor, and it is prone to disease. Under the influence of stress co...

Claims

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Application Information

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IPC IPC(8): A23K20/105A23K20/147A23K20/163A23K40/10A23K40/30
Inventor 赵朋宽雷蕾徐光科赵清国任芳芳张玉芳赵清斌张光彪闫芳陈香华刘杰
Owner 赵清国
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