A kind of preparation method of Shuangxiangpaishi granules

A technology of stone-dispelling granules and talc, which is applied in the field of medicine, can solve the problems of low efficacy of drugs, reduction of active ingredients, waste of medicinal materials, etc., and achieve the effects of reducing production costs, increasing content, and reducing side effects

Active Publication Date: 2018-11-20
JIANGXI JIMINKEXIN PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The problems existing in the existing preparation method are: the curative effect of the medicine is not high, the medicinal materials are wasted, etc., the obtained granules will be pulverized after being stored for a certain period of time, and the active ingredients will be reduced.
For this reason, the applicant improves the existing preparation method, and provides a new preparation method of Shuangxiang Paishi granules, which can improve the curative effect of Shuangxiang Paishi granules, increase the content of active ingredients in Shuangxiang Paishi granules, and at the same time Addressed issues with stability and particle crushing

Method used

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  • A kind of preparation method of Shuangxiangpaishi granules
  • A kind of preparation method of Shuangxiangpaishi granules
  • A kind of preparation method of Shuangxiangpaishi granules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Weigh the raw materials according to the following ratio:

[0060]

[0061]A: Take Xu Changqing, Cinnamon and Muxiang coarsely crushed, add 2 times the water of the medicinal materials, distill for 2 hours, collect the volatile oil, set aside, collect the decoction liquid from the medicinal materials at the same time, add 5 times the water to decoct the medicinal residues for 2 hours, filter, and get The medicinal liquid is combined with the above-mentioned decoction liquid.

[0062] B: frankincense (produced), saffron, psyllium, akebia, shiwei, oatmeal, honeysuckle, talc, mallow seeds, licorice, add 8 times the amount of water, decoct twice, the first time 3 hour, decoct for the second time for 2 hours, combine the decoction, let stand, and filter to obtain the filtrate, where the filtrate and the medicinal solution at A are combined and concentrated to a clear paste with a relative density of 1.31 to 1.34 (80 to 85°C). Take 1 part of clear ointment, 2 parts of suc...

Embodiment 2

[0064] Weigh the raw materials according to the following ratio:

[0065]

[0066]

[0067] A: Take Xu Changqing, cinnamon and woody coarsely, add 7 times 75% ethanol, reflux twice, 1.5 hours each time, collect the reflux liquid, recover ethanol under reduced pressure, concentrate to a relative density of 1.25-1.28 (80-85°C) .

[0068] B: frankincense (produced), saffron, psyllium, akebia, shiwei, oatmeal, honeysuckle, talc, mallow seeds, licorice, add 8 times the amount of water, decoct twice, the first time 3 Hours, decoct for the second time for 2 hours, combine the decoctions, let stand, and filter to obtain the filtrate, which is concentrated to a clear paste with a relative density of 1.31 to 1.34 (80 to 85°C). Mix A and B clear pastes, take 1000g of mixed clear pastes, 1900g of sucrose, and 450g of dextrin, mix them evenly, make soft materials, granulate, dry, and granulate to obtain.

Embodiment 3

[0070] Weigh the raw materials according to the following ratio:

[0071]

[0072] A: Take Xu Changqing, cinnamon and woody coarsely crushed, use 100L of 75% ethanol as a solvent, soak for 72 hours, percolate at a rate of 1-3ml per kilogram per minute, and then continue to add the remaining 75% ethanol 120L for percolation, Collect percolate. Ethanol is recovered from the percolation liquid under reduced pressure, and the concentrated reflux liquid is obtained for future use.

[0073] B: frankincense (produced), saffron, psyllium, akebia, shiwei, oatmeal, honeysuckle, talc, mallow seeds, licorice, add 8 times the amount of water, decoct twice, the first time 3 hour, decoct for the second time for 2 hours, combine the decoction, let stand, and filter to obtain the filtrate, where the filtrate and the medicinal solution at A are combined and concentrated to a clear paste with a relative density of 1.31 to 1.34 (80 to 85°C). Mix A and B clear pastes, take 1000g of mixed clea...

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Abstract

The invention relates to a preparation method of frankincense and elecampane urinary calculus-removing granules. The preparation method comprises the following steps: 1) taking cynanchum paniculatum, cortex cinnamomi and elecampane for coarse crushing, adding water of which the weight is 1-3 times of the total weight of the medicinal materials, distilling for 0.5-2.5 hours, collecting volatile oil for later use, meanwhile collecting decocted liquid of the above medicinal materials, adding 3-6 times of water into medicine residues to decoct for 1-3 hours, filtering to obtain a liquid medicine and merging with the decocted liquid; 2) adding water with a weight of 6-10 times of the total weight of frankincense, nepeta glechoma benth, semen plantaginis, caulis clematidis armandii, pyrrosia lingua, dianthus superbus, caulis lonicerae, talc, chingma abutilon seeds and liquorice, decocting for 1-3 times and 1-3 hours in each time, merging decocted liquid, standing, filtering to obtain a filtrate, merging the filtrate with the liquid medicine in the step 1, concentrating to obtain clear paste, adding a proper amount of auxiliary materials, uniformly mixing, preparing into the granules, drying and spraying the granules with the volatile oil obtained in the step 1.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a preparation method of Shuangxiang Paishi granules. Background technique [0002] Urinary calculus is a common disease of the urinary system. Stones can occur anywhere in the kidneys, bladder, ureters, and urethra. But kidney and ureteral stones are common. Clinical manifestations vary depending on the location of the stone. The typical manifestations of kidney and ureteral stones are renal colic and hematuria. Before the onset of colic caused by stones, the patient does not feel anything. Due to certain inducements, such as strenuous exercise, labor, long-distance driving, etc., sudden severe pain in one side of the waist. Colic, and radiating to the lower abdomen and perineum, accompanied by abdominal distension, nausea, vomiting, and hematuria of varying degrees; bladder stones mainly manifested as dysuria and pain during urination. The effects of Shuangxiang Paishi Granule...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/68A61K9/16A61P13/04A61K33/12
CPCA61K9/1652A61K33/12A61K36/11A61K36/185A61K36/27A61K36/28A61K36/324A61K36/355A61K36/36A61K36/484A61K36/53A61K36/54A61K36/68A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 文万江郭伟杨明何平清惠刚余宣
Owner JIANGXI JIMINKEXIN PHARMA
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