Novelmultifunctional ready-to-useaerogel composite for whole blood component protection and preparation method of novelmultifunctional ready-to-useaerogel composite

Abstract

The invention provides a multifunctional aerogel material for blood component protection and a preparation method of the multifunctional aerogel material. Gellan gum, hyaluronic acid, Pullulan, Lubrajel CG andpoly(gamma-glutamic acid), derivatives or a mixture thereof are taken as a skeleton to act with a novellight-sensitive material, aerogel or a precursor for preparation of the ready-to-useaerogel material, and then multifunctional ready-to-useaerogel composite is prepared from the ready-to-useaerogel material as well as raw materials includingglucose, a novel solvent, a novel fixing agent, a buffering agent, a stabilizer, a novel preservative, a surfactant, a high-molecular compound, essential oil, an antioxidant and the likewith a three-spectral-line high-energy photocuring method by utilizing a high polymer material such as hyaluronic acid and the like as the skeleton. The material has the characteristics of being convenient to use, green, environment-friendly and the like, the whole blood component treated with the material keeps good cellular morphology, is stored for a long time, reducesbatch-to-batch difference and is an ideal additive for a whole blood controlling product and other products, and the material can also be applied to collection, storage and transfer of tissue cells as well as fields of cosmetics, food, drugs and the like.

Description

technical field [0001] The invention belongs to the field of chemical heat insulation, heat preservation, cold storage, moisturizing and protective materials, and specifically relates to a novel airgel blending / coating ready-to-use multifunctional material for blood component protection and a preparation method thereof. . Background technique [0002] Gellan gum is currently one of the food gums with superior performance in the world, which integrates thickening, suspension, emulsification, stabilization, antibacterial, and controlled release. It has extremely high commercial profits and market prospects. Gellan gum is a polysaccharide colloidal gel obtained by biological fermentation. It has the advantages of low dosage, high transparency, strong aroma release ability, acid and alkali resistance, and has anti-microbial and anti-enzymolysis effects, so gellan gum is used The prepared gel can reduce the addition of preservatives in an appropriate amount, not only saves produ...

AI Technical Summary

Problems solved by technology

Although this patent prepares airgel under normal temperature conditions, it still requires a heating step and a multi-stage drying step, and the operation is troublesome and time-consuming

[0034] All of the above methods require heating steps or complicated operations, the preparation process is complex, the process is not suitable for control, the technology involves a small area, the scope of application is narrow, and there are not many studies on the application of functional molecules or material functional blending / coating

Among them, the patent "A Maintenance Solution for Preserving Porcine Whole Blood and Its Application Method" is not suitable for the preparation of five-category blood quality control substances, and the cell morphology and content change significantly after long-term storage, which is not suitable for the preservation of tissue cells; while the patent "A Method for Preparing Large Flexible Aerogels by Drying at Normal Pressure" requires heating and cumbersome operation steps, which can easily cause the collapse or damage of the airgel structure

Images