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Loquat extract and buccal tablet of loquat-black tea extract for glucose lowering prepared therefrom
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The technology of black tea extract and loquat leaf extract is applied in the field of hypoglycemic loquat black tea extract buccal tablets, which can solve problems such as poor taste, and achieve the effects of treating diabetes symptoms, comprehensive efficacy and convenient use.
Active Publication Date: 2017-08-01
ANHUI AGRICULTURAL UNIVERSITY
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As in CN104543197A "A kind of herbal tea containing loquat leaves and its preparation method", CN103719311A "A kind of loquat leafstomach heat health care tea" and CN100366177C "A kind of loquat leaf health care tea", although these compound loquat leaf health care teas have added several other This kind of material has improved efficacy, but also has the problem of poor taste
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Embodiment 1
[0034] Embodiment 1: the preparation of loquat leaf extract
[0035] The preparation method of loquat leaf extract
[0036] (1) loquat leaves are dried and pulverized;
[0037] (2) First adopt 50% ethanol ultrasonic extraction for 25 minutes, centrifuge to obtain the extract, then adopt 75% ethanol to carry out ultrasonic extraction for 15 minutes; wherein the solid-liquid ratio of ultrasonic extraction is 1:10, and the ultrasonic frequency is 45 Hz;
[0038] (3) Combine the extracts, centrifuge the obtained extracts to remove the precipitate, and concentrate under reduced pressure to a low-alcohol concentrated solution with an alcohol content≤30%;
[0039] (4) The low-alcohol concentrated solution is stored at 0°C for 24 hours, the supernatant is removed, and the precipitated part is centrifuged at 3000 rpm for 10 minutes to obtain a precipitate;
[0040] (5) After the precipitate is dried, add 95% ethanol (1:1) at 30°C to dissolve, and add a non-polar macroporous adsorptio...
Embodiment 2
[0042] Embodiment 2: the preparation of loquat leaf extract
[0043] Compared with embodiment 1, only step (2) is different. In this embodiment, step (2) is specifically:
[0044]Use 50% ethanol for ultrasonic extraction, the ratio of solid to liquid is 1:10, the ultrasonic frequency is 45Hz, and the extraction time is 40min.
Embodiment 3
[0045] Embodiment 3: the preparation of loquat leaf extract
[0046] Compared with embodiment 1, only step (2) is different. In this embodiment, step (2) is specifically:
[0047] First, 50% ethanol was used for ultrasonic extraction for 25 minutes, and the extract was obtained by centrifugation, and then 75% ethanol was used for ultrasonic extraction for 15 minutes; the solid-liquid ratio of ultrasonic extraction was 1:10, and the ultrasonic frequency was 25 Hz.
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Abstract
The invention discloses a loquat extract and a buccal tablet of a loquat-black tea extract for glucose lowering prepared therefrom, and belongs to the technical field of food. In this invention, the loquat-black tea extract is prepared by extracting the loquat and the black tea with water, 50% and 75% ethanol sequentially, recovering until the concentration of the ethanol sediments is low, centrifuging, refluxing and decolorizing the precipitate by celite, further adsorbing by macroporous adsorbent resin, eluting with 50% ethanol, and drying the eluent. The buccal tablet is prepared from the the following components in parts by weight: 30 to 40 parts of the loquat-black tea extracts, 50 to 70 parts of microcrystallinecellulose, 0.5 to 1 parts of mannitol, 0.5 to 1 part of magnesiumstearate, 0.5 to 1 part of aspartame, 1 to 5 parts of citric acid, and a preparation method comprises the steps of pre-treatment of the materials, granulation and tablet to obtain a finished product.
Description
technical field [0001] The invention relates to a loquat extract and a loquat black tea extract buccal tablet for reducing blood sugar prepared by the loquat extract, which belongs to the technical field of food. Background technique [0002] Loquat leaf is the dried leaf of Loquat Eriobotryajaponica (Thunb.) Lindl., a plant of the genus Loquat in the family Rosaceae. It is a commonly used traditional Chinese medicine, and it is recorded in the Chinese Pharmacopoeia for clinical use of traditional Chinese medicine. Loquat fruit is edible, loquat flowers can be made into scented tea for drinking, and loquat leaves are also a plant resource for both medicine and food. Symptoms such as stomach heat, vomiting, dysphoria and thirst. Recent studies have found that triterpenoids isolated from loquat leaves have significant hypoglycemic activity. [0003] Type 2 diabetes is a common metabolic disorder in the human body. In traditional Chinese medicine, it belongs to the category o...
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