Preparation method of tea-seed oil for medical injection

A technology of camellia oil for injection, which is applied in the field of preparation of camellia oil for medical injection, can solve the problems of high cost, lack of large-scale industrial production, and unsuitability for mass production, and achieve enhanced mechanical strength, increased reuse rate, The effect of quick and effective removal

Active Publication Date: 2017-09-29
INST OF APPLIED CHEM JIANGXI ACAD OF SCI
View PDF6 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is simple and easy to operate, but there are certain limitations. The samples processed each time are too small, so it is not suitable for mass production, does not have the value of large-scale industrial production, and the cost is high.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0029] The preparation method of camellia oil for medical injection of the present invention comprises the following specific steps:

[0030]Step S1, the crude camellia oil is processed by macroporous adsorption resin column chromatography: the crude camellia oil is extracted from a subcritical fluid, the acid value is 2-4mgKOH / g, the peroxide value is 3-5gmmol / kg, and the color: yellow 30~ 35. Red 2.0-5.0; the pretreated macroporous adsorption resin is loaded into the column, the diameter-to-height ratio of the chromatographic column is 1:20-60, the amount of the macroporous adsorption resin is 1 / 2 of the column height, and the crude camellia oil is loaded into a large column. In the porous adsorption resin column, the camellia oil enters the macroporous adsorption resin column for static adsorption for 30-60 minutes; the macroporous adsorption resin column is eluted with medium and low concentration ethanol added with surfactant until no oil flows out, and the demulsification...

Embodiment 1

[0046] Step 1, AB-8 type macroporous adsorption resin is first soaked with 95% ethanol for 20h, then repeatedly washed with deionized water, then soaked with 5% hydrochloric acid solution for 2h, then with 5% sodium hydroxide solution for 2h, and finally with Wash with deionized water until the pH of the effluent is neutral; put the pretreated AB-8 macroporous adsorption resin into a resin column with a diameter of 3 cm and a length of 65 cm, and the loading amount of the AB-8 macroporous adsorption resin is 1 / 2. Add 100g of camellia oil with an acid value of 2.5mgKOH / g, a peroxide value of 3gmmol / kg, a yellow value of 30, and a red value of 2.0 into the AB-8 resin column, and use a booster pump to make the camellia oil fully enter the large pores Perform static adsorption inside the resin for 30 minutes, then use a solution of 20% ethanol and fatty acid glycerides at a mass ratio of 30:1 to elute the resin column at a flow rate of 5mL / min until no oil flows out, and then cent...

Embodiment 2

[0051] Step 1, XDA-1 type macroporous adsorption resin is first soaked with 95% ethanol for 22 hours, then repeatedly washed with deionized water, then soaked with 5% hydrochloric acid solution for 3 hours, then soaked with 7% sodium hydroxide solution for 2.5 hours, and finally Wash with deionized water until the pH of the effluent is neutral; put the pretreated XDA-1 macroporous adsorption resin into a resin column with a diameter of 3 cm and a length of 105 cm, and the amount of XDA-1 macroporous adsorption resin loaded is 1 / 2, add 100 g of camellia oil with an acid value of 3.0 mgKOH / g, a peroxide value of 4 gmmol / kg, a yellow value of 32, and a red value of 4.0 into the XDA-1 resin column, and use a booster pump to make the camellia oil fully Enter the macroporous resin for static adsorption for 50 minutes, then use a solution made of ethanol and citric acid ester with a mass percentage concentration of 10% at a mass ratio of 50:1 to elute the resin column at a flow rate ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
acid valueaaaaaaaaaa
peroxide valueaaaaaaaaaa
acid valueaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of tea-seed oil for medical injection. The preparation method comprises the following steps: firstly, treating crude tea-seed oil, which is obtained by subcritical fluid extraction, through macroporous adsorption resin column chromatography; adsorbing to remove colloid, water-soluble pigments and part of hydrophobic pigments; collecting light yellow grease; carrying out deacidification and de-coloring on the light yellow grease by utilizing nitrogen-doped tea seed shell active carbon to obtain the colorless and transparent tea-seed oil for the medical injection, which has acid value less than 0.3mgKOH / kg and the peroxide value less than 1.5mmol / kg. The preparation method disclosed by the invention integrates deacidification and de-coloring procedures so that a process flow is simplified, operation conditions are moderate and the production cost is reduced; the pigments in the tea-seed oil are rapidly and effectively removed under normal temperature and normal pressure, the acid value is reduced and aldehyde and ketone type impurities produced in a tea-seed oil oxidization process are removed; the content of oleic acid is improved and the colorless and transparent tea-seed oil for the medical injection is prepared.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a preparation method of camellia oil for medical injection. Background technique [0002] Camellia oil is a fat oil obtained by processing and extracting mature seeds of Camellia Oleifabel. It is a unique woody oil in my country. Camellia oleifera in my country is rich in resources, and the area of ​​camellia oleifera forests accounts for more than 80% of the area of ​​woody edible oil plants. They are widely distributed in southern hilly areas, especially in Guangxi, Guangdong, Hunan, Jiangxi, and Yunnan. Camellia oil fatty acid is mainly composed of 75%-88% oleic acid, 3.5%-21% linoleic acid and 0.3%-1.5% linolenic acid, saturated fatty acid (10%), monounsaturated fatty acid (80% %) and polyunsaturated fatty acids (10%) are closest to the ideal pattern recommended by nutritionists 1:8:1. The fatty acid composition of camellia oil is similar to that of the best olive oil i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & AuthorityApplications(China)
IPC IPC(8): C11B3/00C11B3/10C11B3/16C11B3/12B01J20/20
CPCB01J20/20B01J2220/4881C11B3/001C11B3/006C11B3/10C11B3/12C11B3/16
Inventor韩晓丹熊伟胡居吾王慧宾
OwnerINST OF APPLIED CHEM JIANGXI ACAD OF SCI