Nisin polylysine antibacterial nano particles and preparation method thereof

A nanoparticle and polylysine technology, which is applied in the field of food antibacterial additives, can solve the problems of reducing stability and biological activity, and achieve the effects of good product stability, special product structure and small particle size
CN107668473AInactive Publication Date: 2018-02-09JIANGSU UNIV
5 Cites 8 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU UNIV
Publication Date
2018-02-09
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention belongs to the field of antibacterial additives for foods, and particularly relates to Nisin polylysine antibacterial nano particles high in stability and high baceterium resistance anda preparation method of the Nisin polylysine antibacterial nano particles. According to the Nisin polylysine antibacterial nano particles disclosed by the invention, the characteristics of a charged type natural polymer are used, a static electricity self-assembly technique is adopted, and Nisin embedding polylysine antibacterial nano particles are prepared, so that Nisin can be prevented from generating a bonding reaction or an enzymolysis reaction with food components in practical application, and the stability and the bioactivity of the Nisin can be effectively maintained. The Nisin polylysine antibacterial nano particles disclosed by the invention are simple in preparation technology, good in product stability, uniform in particle size distribution, high in entrapment efficiency and high in drug loading capacity, and have remarkable antibacterial effects on listeria monocytogenes (L.monocytogenes) and staphylococcus aureus (S.aureus) in simulated condensed milk culture mediums.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention belongs to the field of food antibacterial additives, and in particular relates to a Nisin polylysine antibacterial nanoparticle and a preparation method thereof. Background technique

[0002] Nisin, also known as nisin or Nisin, is a polypeptide substance produced by Lactococcus lactis subspecies lactic acid, which belongs to microbial antibacterial substances. It has broad-spectrum antibacterial effect on Gram-positive bacteria, and is natural, safe and efficient. As a polypeptide substance, Nisin will bond or enzymatically react with food ingredients if it is directly applied to food, thereby reducing its stability and biological activity.

[0003] In recent years, nanoparticles, as drug delivery carriers, have attracted extensive attention from researchers due to their small particle size and large specific surface area. Biopolymers (such as polyglutamic acid, polylysine, chitosan, and pectin, etc.) are widely used in the preparatio...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More