Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method capable of improving biological activity of medical porous titanium alloy

A bioactive, titanium alloy technology, applied in medical science, tissue regeneration, metal material coating technology, etc., can solve the problems of porous medical titanium alloy biological activity, etc., and achieve remarkable biological activity, adaptability, and low energy consumption. Effect

Inactive Publication Date: 2018-02-16
NANCHANG HANGKONG UNIVERSITY
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem of bioactivity of porous medical titanium alloys, and provide a preparation method for improving the bioactivity of medical porous Ti-Cu alloys

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0016] Embodiment 1: A preparation method for improving the bioactivity of medical porous titanium alloy is carried out according to the following steps: (1) Porous titanium alloy surface pretreatment: degreasing, SiC sandpaper polishing, mechanical polishing and electrochemical polishing;

[0017] (2) The pretreated porous titanium alloy is used as a coating sample, and pure magnesium is used as a target;

[0018] (3) Vacuum to 6×10 -4 Pa, pass argon to 0.15Pa, pre-sputter to clean the surface of the target for 10 minutes;

[0019] (4) Heat up the heating platform to 200-300°C and keep it warm;

[0020] (5) Adjust the sputtering bias to -100~-300V, the sputtering power to 50~200W, and coat the sample surface for a certain time of 5min~1h;

[0021] (6) After the temperature drops to room temperature, a magnesium film with a certain thickness can be obtained on the inner and outer surfaces of the porous titanium alloy, and the bioactivity of the porous titanium alloy can be ...

specific Embodiment approach 2

[0023] Embodiment 2: The difference between this embodiment and Embodiment 1 is that the porous titanium alloy in step (1) can be porous pure titanium, porous Ti-6Al-4V alloy, porous Ti-6Al-7Nb, porous Ti -Mo-based alloys, porous Ti-Nb-based alloys, porous Ti-Ni-based alloys and other biomedical titanium alloys. Other steps and selected parameters are the same as those in Embodiment 1.

specific Embodiment approach 3

[0024] Embodiment 3: The differences between this embodiment and Embodiment 1 are: the porosity of the porous titanium alloy in step (1) is 30-60%, and the pore diameter is 100-300 μm. Other steps and selected parameters are the same as those in Embodiment 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Apertureaaaaaaaaaa
Average pore sizeaaaaaaaaaa
Average pore sizeaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method capable of improving biological activity of a medical porous titanium alloy. The method comprises the steps that 1, surface pretreatment is conducted on the porous titanium alloy; 2, the porous titanium alloy obtained after pretreatment serves as a film-coated sample, and pure magnesium serves as a target material; 3, vacuum extraction is conducted, argon gas is introduced, pre-sputtering is conducted, and the surface of the target material is cleaned for 10 minutes; 4, the temperature is raised, heating is conducted, and the heat is preserved; 5, the sputtering bias voltage and the sputtering power are adjusted, and film coating is conducted on the surface of the sample for a certain period of time, namely 10 minutes to 1 hour; and 6, after thetemperature is lowered to be the room temperature, magnesium films of a certain thickness can be obtained from the inner surface and the outer surface of the porous titanium alloy, the magnesium films are degraded in body fluid, and biological activity of the porous titanium alloy can be improved. The preparation method has the technical beneficial effects that the preparation method is simple, convenient to implement, high in adaptability, low in energy consumption, suitable for industrial production, remarkable in improvement of biological activity of the porous titanium alloy and the like;and the porous titanium alloy good in biological activity can be used as a material for repairing and substituting hard tissues such as bones, joints and artificial tooth roots.

Description

technical field [0001] The invention relates to a method for preparing a bioactive thin film, in particular to a preparation method for improving the bioactivity of a medical porous titanium alloy. Background technique [0002] Due to its light weight, high specific strength, excellent corrosion resistance and biocompatibility, good toughness and impact resistance and other advantages, titanium alloy has been widely used in human hard tissue transplantation materials. However, there are still two main problems in the clinical application of titanium alloys. First of all, the elastic modulus of titanium alloy is ~110GPa, which is much larger than that of artificial bone (<20GPa), and it is prone to cause stress shielding phenomenon; secondly, titanium alloy is an inert material, has no biological activity, and cannot form osseointegration with bone. In order to solve the problem of stress shielding, the porous structure is introduced into the titanium alloy to form a poro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C23C14/35C23C14/16C22C14/00A61L27/56A61L27/30A61L27/06
CPCC23C14/35A61L27/06A61L27/306A61L27/56A61L2430/02A61L2430/12A61L2430/24C22C14/00C23C14/165
Inventor 徐吉林陶寿晨罗军明
Owner NANCHANG HANGKONG UNIVERSITY