Application of a blood-derived enzymatic peptide in the preparation of drugs for inhibiting intestinal inflammation in animals

Abstract

The invention provides an application of a blood-derived enzymatic hydrolysis peptide in the preparation of a drug for inhibiting intestinal inflammation in animals. Specifically, pig blood is used as a raw material and purified through grinding, enzymolysis, suction filtration, centrifugation, ultrafiltration and other processes to obtain A biologically active peptide that has the effect of inhibiting intestinal inflammation in animals. The dried active peptide is in the form of thin layer, powder, powder with lighter color. The biologically active peptide has the effect of inhibiting intestinal inflammation judged by its inhibitory effect on mouse intestinal inflammation, and can be used as feed, feed additive, pharmaceutical auxiliary material, etc. The blood-derived enzymatic peptide for inhibiting intestinal inflammation of the present invention is non-toxic and has no side effects, does not remain in animals, and has significant economic and social contributions. The invention will promote the rapid development of active peptide biological products in the pharmaceutical industry and the feed industry.

Description

Technical field [0001] The present invention belongs to the field of biopharmaceutical technology, and in particular, a blood source enzymatic hydrolyzide is used in the preparation of inhibiting animal intestinal inflammatory drugs. Background technique [0002] my country produces a large number of meat foods every year, including livestock and poultry, aquatic food, resulting in the main factors in my country's immortal food insecurity is the seriousness of the residue of veterinary drugs. During the process of livestock and poultry, the criminals ignore the national decree to add lean meat in livestock and poultry feed, which is harmful to the human body; in the process of livestock and poultry, it is used to prevent or treat diseases to use antibiotics such as chloramphenicol, soish Sui, etc., although it can effectively prevent corrosion and antibacterial effects, the residue of this drug in the animal, after intake the human body, some in the body cannot be met, carcinogen...

AI Technical Summary

Problems solved by technology

In the process of livestock and poultry breeding, criminals ignore national laws and regulations and add clenbuterol to livestock and poultry feed, causing harm to the human body; in the process of livestock and poultry breeding, antibiotics such as chloramphenicol and terraforming Although it can effectively prevent antiseptic and antibacterial effects, some of the drug residues in the animal body cannot be metabolized in the body after ingestion, causing cancer and causing serious harm to the human body.

However, modern farming tends to be high-density and intensive farming, which makes the breeding body more susceptible to disease and further aggravates the problem of drug residues

However, the use of enzymatic peptides - enzymatic peptides from blood sources as a drug to inhibit intestinal inflammation in animals has not been reported in the literature so far.

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