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Cordyceps militaris polysaccharide micro-capsules and preparation method thereof

A technology of Cordyceps militaris and microcapsules, applied in the field of medicine, can solve the problems of decreased immunity, irregular life, unreasonable diet, etc., and achieve the effect of low cost, large profit margin, and promoting adrenal glands

Inactive Publication Date: 2018-08-17
FOSHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This product is a good solution to the pressure of modern people from work and life, coupled with irregular life, unreasonable diet, lack of sleep and other factors, resulting in the decline of some people's immunity and other problems

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Wash, dry, pulverize Cordyceps militaris, reflux, concentrate, remove protein by Sevag method, centrifuge and other steps to extract polysaccharides from Cordyceps militaris, and precipitate with 4 times ethanol to obtain 2% sulfuric acid group content, 6% uronic acid content, weight A polysaccharide from Cordyceps militaris with an average molecular weight of 750kDa.

[0031] 2. Concentrate the microbial fermentation liquid until the total number of bacteria reaches 5×10 8 cfu / mL.

[0032] 3. Mix the concentrated microbial fermentation broth in step 2 with diatomaceous earth and polyethylene glycol at a ratio of 8% (w / v) and 5% (w / v) respectively, add the polysaccharide from Cordyceps militaris, and homogenize , form the militaris polysaccharide bacterium liquid, wherein the concentration of the militaris polysaccharide is 9g / L.

[0033] 4. Heat up the system in step 3 to 40°C, and mix the militaris militaris polysaccharide solution and the cross-linking salt solu...

Embodiment 2

[0035] 1. Wash, dry, crush, reflux, concentrate, remove protein by Sevag method, centrifuge and other steps to extract the polysaccharide from Cordyceps militaris, and precipitate with 5 times ethanol to obtain a sulfate group content of 3%, an uronic acid content of 7%, and a weight A polysaccharide from Cordyceps militaris with an average molecular weight of 850kDa.

[0036] 2. Concentrate the microbial fermentation liquid until the total number of bacteria reaches 5.5×10 9 cfu / mL.

[0037] 3. Mix the concentrated microbial fermentation liquid in step 2 with diatomaceous earth and polyethylene glycol at a ratio of 8% (w / v) and 5% (w / v) respectively, add the polysaccharide of Cordyceps militaris, homogenize, and form The polysaccharide bacterium liquid of Cordyceps militaris, wherein the concentration of the polysaccharide of Cordyceps militaris is 10g / L.

[0038]4. Heat up the system in step 3 to 40°C, and mix the militaris polysaccharide solution and the cross-linking sal...

Embodiment 3

[0040] 1. Wash, dry, pulverize Cordyceps militaris, reflux, concentrate, remove protein by Sevag method, centrifuge and other steps to extract polysaccharides from Cordyceps militaris, and precipitate with 6 times ethanol to obtain a sulfate group content of 4%, an uronic acid content of 8%, and a weight A polysaccharide from Cordyceps militaris with an average molecular weight of 950kDa.

[0041] 2. Concentrate the microbial fermentation broth until the total number of bacteria reaches 6×10 10 cfu / mL.

[0042] 3. Mix the concentrated microbial fermentation liquid in step 2 with diatomaceous earth and polyethylene glycol at a ratio of 8% (w / v) and 5% (w / v) respectively, add the polysaccharide of Cordyceps militaris, homogenize, and form The polysaccharide bacterium liquid of Cordyceps militaris, wherein the concentration of the polysaccharide of Cordyceps militaris is 11g / L.

[0043] 4. Warm up the system in step 3 to 40°C, and mix the polysaccharide solution of Cordyceps mi...

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Abstract

The invention discloses cordyceps militaris polysaccharide micro-capsules and a preparation method thereof. The cordyceps militaris polysaccharide micro-capsules are prepared by the following steps ofuniformly mixing microbial fermentation liquid with diatomite and polyethylene glycol; adding cordyceps militaris polysaccharides, and carrying out homogenization so as to obtain cordyceps militarispolysaccharide bacterium fluid; and then, heating the system, uniformly mixing the heated material with a cross-linked salt solution so as to realize embedding, and carrying out drying so as to obtainthe cordyceps militaris polysaccharide micro-capsules. The cordyceps militaris polysaccharide micro-capsules are safe and healthy to eat, as well as aromatic and mellow in taste. The cordyceps militaris polysaccharide micro-capsules have certain health-caring effects, and are capable of enhancing human body immunity, improving respiratory system, promoting adrenal gland and inhibiting tumor growth; moreover, the cordyceps militaris polysaccharide micro-capsules also have the pharmacological actions of resisting inflammation, bacteria, tumor, radiation and virus, as well as reducing blood glucose and so on. The nutritional values and the health-caring functions of cordyceps militaris are especially improved by the cordyceps militaris polysaccharide micro-capsules in the aspect of enhancingimmunity; and thus, the cordyceps militaris polysaccharide micro-capsules have very good market and development prospects.

Description

technical field [0001] The invention belongs to the technical field of medicine, and more specifically relates to a polysaccharide microcapsule of Cordyceps militaris and a preparation method thereof. Background technique [0002] As the pace of our life continues to accelerate and the pressure continues to increase, the immune regulation function of many people has also begun to weaken. Because the nutritional content of Cordyceps militaris is very similar to that of Cordyceps militaris, the market price is low and large-scale artificial cultivation has been realized. It is a substitute of high nutritional value, natural, and the cost of mature cultivation technology is low. It is also a strain with strong development potential in edible fungi. Because it is a natural product with both medicine and food, it has no toxic and side effects. Development plays a role that cannot be ignored, and its market development prospects are very broad. With the in-depth research on the f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/125A23L31/00A23P10/30A61K9/50A61K31/715A61K47/06A61K47/10A61P3/10A61P11/00A61P29/00A61P31/04A61P31/10A61P31/12A61P35/00A61P37/04A61P39/00A61P39/06A61P43/00
CPCA23L31/00A23L33/125A23P10/30A23V2002/00A61K9/50A61K31/715A61K47/02A61K47/10A61P3/10A61P11/00A61P29/00A61P31/04A61P31/10A61P31/12A61P35/00A61P37/04A61P39/00A61P39/06A61P43/00A23V2250/208
Inventor 钟先锋江志彬冯结铧黄桂东吴子蓥唐素婷
Owner FOSHAN UNIVERSITY