Green multifunctional teaching microchip preparation method

Abstract

The invention discloses a green multifunctional teaching microchip preparation method. The method include steps: 1) adopting coreldraw software for chip design, and integrally designing chip microstructures required by teaching contents including thin layer chromatography, Lambert-Beer law, chemical reaction rate and the like on a chip; 2) adopting a normal photoetching machine for photoetching toprepare a chip female mould; 3) pouring PDMS (polydimethylsiloxane) on the mould, preparing a PDMS chip male mould after curing, and assembling to obtain a final male mould; 4) pouring polyester resin to the final male mould to obtain a polyester resin based teaching microchip. The microchip prepared according to the method has advantages that 1, small chip size, low reagent consumption and environmental friendliness are realized; 2, the chip integrates more functions; 3, due to adoption of the normal photoetching machine, chip mould manufacturing cost is low; 4, by mould design improvement,low-cost polyester resin can be adopted as a chip manufacturing material, so that total chip production cost is reduced.

Description

Technical field [0001] The invention belongs to the technical field of chemistry teaching appliances, and specifically relates to a preparation method of a green multifunctional teaching microchip. Background technique [0002] This technology belongs to the cross-field of miniaturized chemical reaction device and microfluidic chip technology. Its main idea is to use the production technology of microfluidic chip to make new miniaturized analytical chemistry teaching instruments. Manz A et al. in the early 1990s The concept of miniaturized total analysis system (μ-TAS) was first proposed. Among them, the microfluidic chip integrates analytical chemistry, micro-electro-mechanical system (mi-cro-electro-mechanical system, MEMS), computer, materials science, biomedicine and other multidisciplinary fields, and integrates various functions of the chemical laboratory such as sample prediction Processing, sample injection, separation and detection, etc., are integrated on a credit card...

AI Technical Summary

Problems solved by technology

However, miniaturized devices generally still need supporting facilities such as water and electricity, which cannot be brought into the classroom for experiments. At the same time, the equipment needs to be specially made, so the price is also relatively expensive, and teachers and students cannot realize the self-design of the reaction device.

[0004] Therefore, how to combine the concept of miniaturized chemical experiments with the technology of microfluidic chips to design microchips for teaching is very meaningful. If the microchips for scientific research are directly used for teaching, the cost is high and often There are shortcomings such as unobvious phenomena and poor pertinence. Based on this, we have designed and invented three generations of teaching microchips, introducing microfluidic chip technology into the teaching field, which is innovative. We have applied for a Chinese invention patent with a publication number of CN106563516A, a utility model patent Three items: the publication numbers are CN206293074U, CN206285925U and CN206441437U respectively, but due to technical limitations, the chips prepared by these methods are relatively rough and have single functions, so they can only be constructed with polydimethylsiloxane (PDMS) with good transparency and easy peeling , so the higher cost

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