Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Dual-network hydrogel with high-toughness, shape-memory and self-repairing characteristics and preparation method of dual-network hydrogel

A dual-network and hydrogel technology, applied in the field of double-network hydrogel and its preparation, can solve the problems of poor mechanical properties and limit the application range of chitosan-based hydrogel, and achieve improved mechanical properties and good mechanical properties and self-healing performance, widening the effect of the application range

Active Publication Date: 2018-11-02
ZHEJIANG UNIV
View PDF7 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The single-network hydrogel based on imine bonds constructed by chitosan amino groups and gelling factors containing aldehyde groups has excellent self-healing ability; however, the hydrogel is only constructed of a single network, and its mechanical properties are poor , only suitable for cell culture, which greatly limits the application range of chitosan-based hydrogels

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Dual-network hydrogel with high-toughness, shape-memory and self-repairing characteristics and preparation method of dual-network hydrogel
  • Dual-network hydrogel with high-toughness, shape-memory and self-repairing characteristics and preparation method of dual-network hydrogel
  • Dual-network hydrogel with high-toughness, shape-memory and self-repairing characteristics and preparation method of dual-network hydrogel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] 1) Weigh 4g of chitosan with a viscosity-average molecular weight of 10w and a deacetylation degree of 85%, and disperse it in 200mL of deionized water, add 5.84mL (85.2mmol) of acrylic acid, stir and dissolve, and react at 50°C for 3 days. After the reaction, the pH of the product was adjusted to 10-12 with sodium hydroxide solution, then transferred to a dialysis bag for dialysis for 3 days, freeze-dried to obtain N-carboxyethyl chitosan (CEC);

[0025] 2) Dissolve 6.52g (1.63mmol) polyethylene glycol (PEG4000), 0.98g (6.52mmol) 4-formylbenzoic acid, 0.05g (0.407mmol) 4-(dimethylamino)pyridine (DMAP) in 200mL in anhydrous tetrahydrofuran. Under nitrogen atmosphere, 1.68g (8.15mmol) of N,N'-dicyclohexylcarbodiimide (DCC) was added, and reacted at 20°C for 18h. After the reaction, the white solid was filtered off to obtain a filtrate containing the product. The filtrate was precipitated with ether, and the filter cake obtained by filtration was dissolved in tetrahydro...

Embodiment 2

[0032] 1) Weigh 4g of chitosan with a viscosity-average molecular weight of 10w and a deacetylation degree of 95%, and disperse it in 200mL of deionized water, add 5.84mL (85.2mmol) of acrylic acid, stir and dissolve, and react at 50°C for 3 days. After the reaction, the pH of the product was adjusted to 10-12 with sodium hydroxide solution, then transferred to a dialysis bag for dialysis for 3 days, freeze-dried to obtain N-carboxyethyl chitosan (CEC);

[0033] 2) Dissolve 6.52g (1.63mmol) polyethylene glycol (PEG4000), 0.98g (6.52mmol) 4-formylbenzoic acid, 0.05g (0.407mmol) 4-(dimethylamino)pyridine (DMAP) in 200mL in anhydrous tetrahydrofuran. Under nitrogen atmosphere, 1.68g (8.15mmol) of N,N'-dicyclohexylcarbodiimide (DCC) was added, and reacted at 20°C for 18h. After the reaction, the white solid was filtered off to obtain a filtrate containing the product. The filtrate was precipitated with ether, and the filter cake obtained by filtration was dissolved in tetrahydro...

Embodiment 3

[0039] 1) Weigh 4g of chitosan with a viscosity-average molecular weight of 100w and a deacetylation degree of 50% and disperse it in 200mL of deionized water, add 5.84mL (85.2mmol) of acrylic acid and stir to dissolve, and react at 50°C for 3 days. After the reaction, the pH of the product was adjusted to 10-12 with sodium hydroxide solution, then transferred to a dialysis bag for dialysis for 3 days, freeze-dried to obtain N-carboxyethyl chitosan (CEC);

[0040] 2) Dissolve 3.27g (1.63mmol) polyethylene glycol (PEG2000), 0.98g (6.52mmol) 4-formylbenzoic acid, 0.05g (0.407mmol) 4-(dimethylamino)pyridine (DMAP) in 200mL in anhydrous tetrahydrofuran. Under nitrogen atmosphere, 1.68g (8.15mmol) of N,N'-dicyclohexylcarbodiimide (DCC) was added, and reacted at 20°C for 18h. After the reaction, the white solid was filtered off to obtain a filtrate containing the product. The filtrate was precipitated with ether, and the filter cake obtained by filtration was dissolved in tetrahyd...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Tensile strengthaaaaaaaaaa
Tensile strengthaaaaaaaaaa
Tensile strengthaaaaaaaaaa
Login to View More

Abstract

The invention discloses dual-network hydrogel with high-toughness, shape-memory and self-repairing characteristics and a preparation method of the dual-network hydrogel. The dual-network hydrogel is formed by alternate arrangement of dual networks, a first network is a dynamic imine linkage network formed by Schiff base reaction of chitosan and polyethylene glycol with aldehyde groups at two ends,and a second network is a polyacrylamide cross-linked network. The preparation method mainly includes: dissolving N-carboxyethyl chitosan, acrylamide, N,N'-methylene bisacrylamide into water according to a certain proportion, and adding modified polyethylene glycol and ammonium persulfate mixed solution; performing reaction at 30-50 DEG C to obtain the dual-network hydrogel. The dual-network hydrogel prepared according to the preparation method is excellent in mechanical performance and self-repairing performance and has a shape memory performance of pH and metal ion stimulation response, anapplication range of chitosan self-repairing hydrogel materials is further expanded, and the dual-network hydrogel is hopefully applied to fields of wearable flexible electronic devices, software robots, biomedicine, aerospace engineering and the like.

Description

technical field [0001] The invention relates to a double-network hydrogel, in particular to a double-network hydrogel with high strength, shape memory and self-repairing properties and a preparation method thereof. Background technique [0002] In recent years, self-healing hydrogel materials, as a very important soft material, have great potential application value in electronic skin, wearable flexible devices, biomedicine and other fields. The currently reported self-healing hydrogel materials have problems such as low mechanical strength, single performance, and poor self-healing performance, which greatly limit their application range. Therefore, the development of multifunctional high-strength self-healing hydrogel materials has important scientific significance and application value. [0003] As the only natural weakly alkaline polysaccharide in nature, chitosan contains a large amount of amino groups and hydroxyl groups, and its raw materials are abundant and easy to...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08J3/075C08F291/12C08F220/56C08F222/38C08G65/332C08G65/333C08B37/08C08L51/00
CPCC08B37/003C08F283/06C08F289/00C08G65/3326C08G65/333C08G65/33317C08G2650/04C08J3/075C08J2351/00C08J2351/08C08J2451/00C08J2451/08C08F220/56C08F222/385
Inventor 王征科傅倍佳程宝校金晓强鲍晓炯乔丰慧周一姜质琦胡巧玲
Owner ZHEJIANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com