Feed additive for preventing and treating diseases and capable of substituting antibiotics and preparation method of feed additive

A technology that replaces antibiotics and feed additives. It is applied in animal feed, antiviral agents, animal feed, etc. It can solve the problems of not paying attention to the conditioning and repair of immunity, difficult absorption of active ingredients, and small antibacterial spectrum of Chinese herbal medicine, so as to achieve recovery and promotion. The effect of animal growth, conditioning and restoration of immunity, and improvement of feed conversion rate

Inactive Publication Date: 2018-11-23
四川达邦生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of existing immunization means and treatment methods are as follows: 1. For a long time, veterinary medicine usually adopts antimicrobial drugs for treatment, but with the long-term application of antibiotics, drug-resistant strains are produced and the curative effect is reduced. Drug residues in livestock and poultry products pose a serious threat to human health; 2. A single Chinese herbal medicine has a small antibacterial spectrum and has poor curative effect on current multi-pathogenic infections, so it is mostly used as an adjuvant treatment drug; Poor resistance, the active ingredients are not easy to absorb; 4, do not pay attention to the conditioning and repair of immunity

Method used

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  • Feed additive for preventing and treating diseases and capable of substituting antibiotics and preparation method of feed additive
  • Feed additive for preventing and treating diseases and capable of substituting antibiotics and preparation method of feed additive
  • Feed additive for preventing and treating diseases and capable of substituting antibiotics and preparation method of feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The traditional Chinese medicine components and their mass parts are: 35 parts of eucommia leaves, 30 parts of Sichuan cinnamon bark, and 35 parts of wintergreen leaves.

[0038] Pretreatment of Chinese herbal medicines:

[0039] Dry all the traditional Chinese medicines at 40-50 degrees until the water content is less than 10%, crush them through a 120-mesh sieve, and mix the sieved Chinese medicines evenly according to the ratio of parts by mass;

[0040] Molasses pretreatment:

[0041] Dilute the molasses with 65% solid content and 25% sucrose content with drinking water into a molasses solution with a mass concentration of 20% for subsequent use;

[0042] Preparation of complex enzymes:

[0043] Mix cellulase, hemicellulase, pectinase and fructosyltransferase in a mass ratio of 1:0.8:0.2:0.8 and set aside;

[0044] Enzymolysis:

[0045] Put the mixed traditional Chinese medicine powder into the fermenter, add molasses solution until the water content of the syst...

Embodiment 2

[0047] The preparation method and steps of the Chinese medicine of embodiment 2, molasses and fermentation enzyme are the same as embodiment one;

[0048] Enzymolysis:

[0049] Put the mixed traditional Chinese medicine powder into a fermenter, add molasses solution until the water content of the system is 60%, soak for 2 hours, adjust the pH value to 5.5, and steam sterilize at 121°C for 20 minutes. After cooling, add 1.25% of the traditional Chinese medicine compound Enzyme, 4 hours of enzymolysis at 35-40°C, 10 hours of enzymolysis at 40-45°C, 10 hours of enzymolysis at 45-50°C, stirring once every 1 hour; after the end of the enzymolysis, spray drying to obtain the feed additive.

Embodiment 3

[0051] The preparation method and steps of the Chinese medicine, molasses and fermentation enzyme of embodiment 3 are the same as embodiment one

[0052] Enzymolysis:

[0053] Put the mixed traditional Chinese medicine powder into a fermenter, add molasses solution until the water content of the system is 70%, soak for 2 hours, adjust the pH value to 6.0, and steam sterilize at 121°C for 20 minutes. After cooling, add compounded Enzyme, 4 hours of enzymolysis at 35-40°C, 10 hours of enzymolysis at 40-45°C, 10 hours of enzymolysis at 45-50°C, stirring every 1 hour, after the end of enzymolysis, spray drying to obtain the feed additive.

[0054] The feed additive prepared by the above method was used for experiment.

[0055] 1. Antibacterial test in vitro:

[0056] Table 1 Bacterial strains used in antibacterial experiments

[0057]

[0058]

[0059] Table 2 In vitro antibacterial test bacterial species and the control group drugs used by the disk method

[0060] ...

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Abstract

The invention provides a feed additive for preventing and treating diseases and capable of substituting antibiotics and having the advantages of stable and reliable effect and fast effect, and a preparation method of the feed additive, and relates to the field of animal feed additives. The feed additive is prepared from a traditional Chinese medicine formula and molasses through a compound enzymeenzymolysis process, and has the functions of resisting bacteria and viruses and regulating and repairing immunity, regulating intestines and promoting growth, improving the aroma and palatability oftraditional Chinese medicines and the like, and can effectively solve the defects of the prior art of easy residue in livestock and poultry, generation of drug resistance, potential hazard to the foodsafety of human and the like.

Description

technical field [0001] The invention relates to the technical field of feed additives, in particular to a feed additive that can prevent and treat diseases and can replace antibiotics and a preparation method thereof. Background technique [0002] In recent years, with the development of animal husbandry science and technology, the prevention of livestock and poultry diseases has been greatly improved. However, a large number of livestock and poultry still die every year due to diseases, causing significant economic losses. Therefore, it is necessary to improve the therapeutic effect of livestock and poultry diseases while reducing or avoiding the use of antibiotics as much as possible. [0003] For the above-mentioned problems in animal husbandry, there is no effective and safe immunization method and treatment method at present, and drug treatment is still the main prevention method. The disadvantages of existing immunization means and treatment methods are as follows: 1...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/30A23K10/33A23K10/14A23K10/12A61K36/54A61P31/04A61P31/12
CPCA61K36/185A61K36/46A61K36/54A61K2236/19A23K10/12A23K10/14A23K10/30A23K10/33A61P31/04A61P31/12A61K2300/00Y02P60/87
Inventor 肖体忠
Owner 四川达邦生物科技有限公司
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