Check patentability & draft patents in minutes with Patsnap Eureka AI!

A kind of medicine packaging film and preparation method thereof

A technology for packaging films and medicines, which is applied in the direction of coating, etc., can solve the problems of complex coating process, poor barrier performance of packaging films, poor coating effect of graphene coating, etc., to reduce water vapor transmission rate, coating Good effect, excellent imitation effect of non-selective adhesion performance of mussels

Active Publication Date: 2021-02-19
SICHUAN HUILI IND
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a pharmaceutical packaging film and a preparation method thereof, to solve the problems of poor barrier properties of existing packaging films, poor coating effect of graphene coating, and complicated coating process

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of medicine packaging film and preparation method thereof
  • A kind of medicine packaging film and preparation method thereof
  • A kind of medicine packaging film and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Preparation of hyperbranched cationic mussel-like polymer P1:

[0073]2,3,4-Trihydroxybenzoyl-isobenzoyl-(2-aminoethyl)acrylamide, N-(2-aminoethyl)(meth)acrylamide hydrochloride, 4-azide 2,3,5,6-tetrafluorobenzoylethylamine (meth)acrylamide, polyethylene glycol methyl ether acrylate (PEGMEA), polyethylene glycol diacrylate (PEGDEA, ethylene glycol The degree of polymerization is 22) and the RAFT reagent is added to the N,N-dimethylformamide solution with the concentration of 0.012M as the initiator 4,4'-azobis(4-cyanovaleric acid). Among them, the degree of polymerization of ethylene glycol in PEGMEA is 15, the degree of polymerization of ethylene glycol in PEGDEA is 22, 4,4'-azobis(4-cyanovaleric acid), RAFT reagent and all monomers involved in polymerization The molar ratio of the first reaction mixture is 1:2:100. 2,3,4-trihydroxybenzoyl-isobenzoyl-(2-aminoethyl)acrylamide:N-(2-aminoethyl) (Meth)acrylamide hydrochloride: 4-azido-2,3,5,6-tetrafluorophenacylethylamin...

Embodiment 2

[0080] Preparation of hyperbranched cationic mussel-like polymer P2:

[0081] 2,3,4-trihydroxybenzoyl p-benzamide ethyl (meth)acrylamide hydrochloride, N-(3-aminopropyl) (meth)acrylamide hydrochloride, 4- Nitro-2,3,5,6-tetrafluorobenzoylethylamine (meth)acrylamide, polyethylene glycol methyl ether acrylate (PEGMEA), polyethylene glycol diacrylate (PEGDEA) and RAFT The reagent is added to the N,N-dimethylformamide solution with the concentration of 0.012M of the initiator 2,2'-azobis(2-methylpropionitrile). Among them, the degree of polymerization of ethylene glycol in PEGMEA is 45, the degree of polymerization of ethylene glycol in PEGDEA is 10, 2,2'-azobis(2-methylpropionitrile), RAFT reagent and all monomers participating in polymerization The molar ratio of the first reaction mixture is 1:2:100. 2,3,4-trihydroxybenzoylbenzamide ethyl (meth)acrylamide hydrochloride: N-(3-aminopropyl) (Meth)acrylamide hydrochloride: 4-azido-2,3,5,6-tetrafluorophenacylethylamine (meth)acryla...

Embodiment 3

[0089] Preparation of hyperbranched cationic mussel-like polymer P3:

[0090] 2,3-Dihydroxybenzoylbenzoate amine ethyl (meth)acrylamide hydrochloride, N-(4-aminobutyl) (meth)acrylamide hydrochloride, 4-azide Base-phenacylethylamine (meth)acrylamide, polyethylene glycol methyl ether acrylate (PEGMEA), polyethylene glycol diacrylate (PEGDEA) and RAFT reagent 2-(dodecyltrithio Carbonate group)-2-methylpropionic acid was added to the N,N-dimethylformamide solution with a concentration of 0.012M of the initiator 2,2'-azobis(2-methylpropionitrile). Among them, the degree of polymerization of ethylene glycol in PEGMEA is 5, the degree of polymerization of ethylene glycol in PEGDEA is 8, 2,2'-azobis(2-methylpropionitrile), RAFT reagent and all monomers participating in polymerization The molar ratio of the first reaction mixture is 1:2:100. 2,3-Dihydroxybenzoylbenzoate amine ethyl(meth)acrylamide hydrochloride: N-(4-aminobutyl) (Meth)acrylamide hydrochloride: 4-azido-phenacylethylam...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
degree of polymerizationaaaaaaaaaa
Login to View More

Abstract

The invention discloses a medicine packaging film and a preparation method thereof, wherein the medicine packaging film comprises a polymer film and a graphene coating coated on the polymer film, and the graphene coating comprises graphene and light-cured adhesive agent, the photocurable adhesive includes a hyperbranched cationic mussel-like polymer, and the hyperbranched cationic mussel-like polymer includes a poly-o-phenolic hydroxybenzophenone enamide monomer, a cationic monomer, and a photoresponsive unit body. The photocurable adhesive prepared by the hyperbranched cationic mussel-like polymer in the present invention significantly increases the bonding strength of the photocurable adhesive and the polymer film, thereby, the graphene composed of the photocurable adhesive and graphene The combination of the coating on the polymer film is stronger and the coating effect is better. At the same time, because the coating effect is significantly improved, the preparation process of the pharmaceutical packaging film is simplified to a certain extent.

Description

technical field [0001] The invention relates to the field of packaging materials, in particular to a medicine packaging film and a preparation method thereof. Background technique [0002] As the main packaging material of pharmaceuticals, polymer film packaging materials have become more and more important in daily life. However, due to the influence of the plastic film production process and its own physical and chemical characteristics, it is difficult for the barrier properties of plastics to oxygen, water vapor, liquid substances and other low molecular weight substances to meet the requirements of most pharmaceutical packaging. The penetration of small molecular gases such as oxygen and water vapor into packaging materials will lead to oxidative deterioration of the active ingredients in the drug, which in turn will cause the reproduction of microorganisms and other phenomena. The direct consequence is that the shelf life of the drug is greatly shortened. Therefore, i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08J7/048C08J5/18C09D151/08C09D7/61C08L23/12C08L23/06C08L67/02C08L27/06
CPCC08J5/18C08J2323/06C08J2323/12C08J2327/06C08J2367/02C08J2451/08C08K3/042C08J7/0427
Inventor 张辉柏金枝闫斌
Owner SICHUAN HUILI IND
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More