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Starch-based hollow capsule with high toughness and being easy to decompose

A hollow capsule, starch-based technology, applied in the field of biomedicine, can solve problems such as harm to human health, and achieve the effects of good stability, improved processing characteristics, and beneficial drug release.

Inactive Publication Date: 2019-01-29
HEFEI HUAGAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the addition of plasticizers in food and medicine may cause harm to human health

Method used

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  • Starch-based hollow capsule with high toughness and being easy to decompose

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Experimental program
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Effect test

Embodiment 1

[0031] A starch-based hollow capsule with high toughness and easy decomposability. According to the mass percentage, the raw material components of the hollow capsule include: 45% modified starch, 5% cactus flower extract, 5% gelling agent, 1.5% coagulation aid, chitosan Sugar 1.2%, antioxidant 0.05%, and the balance is deionized water.

[0032] In the present embodiment, the preparation method of cactus flower extract comprises the following steps:

[0033] (1) Select fully open cactus flowers, pick the complete flowers with the receptacle, and remove the petals for subsequent use;

[0034] (2) After chopping the flowers treated in the previous step, add them to the reaction kettle, add 20 times the volume of distilled water into the reaction kettle, and add salicylic acid accounting for 3.5% of the flower mass, heat to boiling and cook for 160 minutes;

[0035] (3) Filtrate the cooking liquid in the previous step to remove residue, then add 3%wt sodium tripolyphosphate to t...

Embodiment 2

[0047] A starch-based hollow capsule with high toughness and easy decomposability. According to the mass percentage, the raw material components of the hollow capsule include: modified starch 65%, cactus flower extract 12.5%, gelling agent 7%, coagulation aid 1.9%, chitosan Sugar 1.5%, antioxidant 0.2%, food coloring 1.5%, and the balance is deionized water.

[0048] In the present embodiment, the preparation method of cactus flower extract comprises the following steps:

[0049] (1) Select fully open cactus flowers, pick the complete flowers with the receptacle, and remove the petals for subsequent use;

[0050] (2) After chopping the flowers treated in the previous step, add them to the reaction kettle, add 30 times the volume of distilled water into the reaction kettle, and add salicylic acid accounting for 4.7% of the flower mass, heat to boiling and cook for 220 minutes;

[0051] (3) Filter the cooking liquor in the previous step to remove residue, then add 4.5%wt sodium...

Embodiment 3

[0063] A starch-based hollow capsule with high toughness and easy decomposability. According to the mass percentage, the raw material components of the hollow capsule include: 55% modified starch, 8.5% cactus flower extract, 6% gelling agent, 1.7% coagulation aid, chitosan Sugar 1.4%, antioxidant 0.11%, food coloring 0.8%, and the balance is deionized water.

[0064] In the present embodiment, the preparation method of cactus flower extract comprises the following steps:

[0065] (1) Select fully open cactus flowers, pick the complete flowers with the receptacle, and remove the petals for subsequent use;

[0066] (2) After chopping the flowers treated in the previous step, add them to the reaction kettle, add 25 times the volume of distilled water into the reaction kettle, and add salicylic acid accounting for 4.2% of the flower mass, heat to boiling and cook for 190 minutes;

[0067] (3) Filter the cooking liquor in the previous step to remove residue, then add 3.8%wt sodium...

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Abstract

The invention relates to the technical field of biological medicine, in particular to a starch-based hollow capsule with high toughness and being easy to decompose. The starch-based hollow capsule isprepared from the raw materials in percentage by mass: 45-65% of modified starch, 5-12.5% of cactus flower extract, 5-7% of a gelatinizing agent, 1.5-1.9% of a condensation additive, 1.2-1.5% of chitosan, 0.05-0.2% of antioxygen, 0-1.5% of edible pigment, and the balance of deionized water. The cactus flower extract is a polysaccharide substance extracted from cactus flower receptacles and ovaries, and has a good film forming effect and hygroscopicity. The modified starch is hydroxypropyl starch. The gelatinizing agent adopts one of xanthan gum, carrageenan, pectin, guar gum, konjac glucomannan and mannan, or is a mixture of the multiple materials. The antioxygen is one of ascorbate, carotene, lecithin and tea polyphenol. The starch-based hollow capsule is high in strength and excellent intoughness, is prepared from plant source materials, and is free of plasticizer and other chemical raw materials, thereby being safer and healthier.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a starch-based hollow capsule with high toughness and easy decomposability. Background technique [0002] Capsule is a new type of packaging material, which is widely used in the fields of medicine and health food, and is mainly used as sub-packaging of quantitative drugs. Capsules can be used for the packaging of solid powders, solutions, suspensions, emulsions and other dosage forms of drugs. After ingestion, the contents can be released quickly, and the utilization rate and absorption rate in the body are high. [0003] Conventional empty capsule packaging materials are mainly made of edible gelatin, glycerin or other suitable auxiliary materials alone or mixed; this packaging has good toughness and strength, and is not easy to break. Gelatin has been used for a long time in the preparation of capsules. Edible gelatin is mainly made of animal fur or bones and other tissue...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/36A61K47/46A23P10/30A61J3/07
CPCA23P10/30A61J3/077A61K9/4816A61K47/36A61K47/46
Inventor 张安育
Owner HEFEI HUAGAI BIOTECH CO LTD